The Institute for Clinical and Experimental Research® is focused on the development of new diagnostic assays in a wide range of disciplines. Researchers at the institute regularly publish in respected, peer-reviewed journals, give presentations at national and international organizations, author books and book chapters, and develop new tests.

Publications by Year

2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021

Recent Publications

Kaczmarczyk A, Baker M, Diddle J, Yuzyuk T, Valle D, Lindstrom K. A neonate with ornithine aminotransferase deficiency; insights on the hyperammonemia-associated biochemical phenotype of gyrate atrophy. Molecular Genetics and Metabolism Reports 2022;31 (2022) 100857.

Abbott J, Corean J, Laggis C, Halwani A, Toydemir R, Miles R, Florell S, Wada D. Histological Transformation and Clonal Relationship of Subcutaneous Marginal Zone B-Cell Lymphoma and Diffuse Large B-Cell Lymphoma. The American Journal of Dermatopathology 2022;44(6):442-448.

Kukull B, Shakir SM, Hanson KE. Performance of Non-nasopharyngeal Sample Types for Molecular Detection of SARS-CoV-2. Clinics in Laboratory Medicine 2022;42(2):249-259.

Kushnir MM, Clarke NJ, Rockwood AL, Mass spectrometry. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 7th edition. Editors Nader Rifai, Rossa WK Chiu, Ian Young, Carey-Ann D Burnham and Carl T Witwer. Philadelphia: W.B. Saunders Company. 2022;271-295.

Profaizer T, Lazar-Molnar E. Quantifying Donor-Derived Cell-Free DNA in Solid Organ Transplant Recipients. ASHI Quarterly 2022;46(2):13-17.

Mathison BA, Pritt BS. Chapter 88: Parasitology. Pp 1205. In: Rifai N, Chiu RWK, Young I, Burnham CD, Whittwer CT (eds.). Tietz Textbook of Laboratory Medicine, 7th edition. St. Louis: Elsevier. 2022. 1547 pp. [full chapter available on]

Jaskowski TD, Christensen BB, Tebo AE. 56-Year-Old Man with Unexplained Proteinuria. Journal of Applied Laboratory Medicine 2022;7(1):331-335.

Li P, Venkatachalam S, Ospina Cardona D, Wilson L, Kovacsovics TJ, Moser KA, Miles RR, Beck DB, George TI, Tantravahi SK. A clinical, histopathological, and molecular study of two cases of VEXAS syndrome without a definitive myeloid neoplasm. Blood Advances 2022;6(2):405-409.

Izadi N, Knight V, Strand M, Hill HR, Peterson LK, Hauck PJ. An Enzyme-Linked ImmunoSpot Assay (ELISPOT) to Assess Pneumovax® Response when on Intravenous Immunoglobulin. Annals of Allergy, Asthma & Immunology 2022;128(1):61-67.e4.

Ward A, Velinder M, Di Sera T, Ekawade A, Malone Jenkins S, Moore B, Mao R, Bayrak-Toydemir P, Marth G. A Collaborative Diagnostic Workflow to Enable Team-Based Precision Genomics. Journal of Personalized Medicine 2022;12(1):73.

Wilcock DM, Schmidt RL, Furtado LV, Matynia AP, Deftereos G, Sirohi D. Histologic and Molecular Characterization of Non-Small Cell Lung Carcinoma With Discordant ROS1 Immunohistochemistry and Fluorescence In Situ Hybridization. Applied Immunohistochemistry & Molecular Morphology 2022;30(1):19-26.

Cushman-Vokoun A, Lauring J, Pfeifer J, Olson DR, Berry A, Thorson J, Voelkerding K, Myles J, Barbeau J, Chandra P, Li M, Vance GH, Jensen BW, Hansen MY, Yohe S. Laboratory and Clinical Implications of Incidental and Secondary Germline Findings During Tumor Testing. Archives of Pathology & Laboratory Medicine 2022;146(1):70-77.

Smid MC, Metz TD, McMillin GA, Mele L, Casey BM, Reddy UM, Wapner RJ, Thorp JM, Saade GR, Tita ATN, Miller ES, Rouse DJ, Sibai B, Costantine MM, Mercer BM, Caritis SN; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Network. Prenatal Nicotine or Cannabis Exposure and Offspring Neurobehavioral Outcomes. Obstetrics and Gynecology 2022;139(1):21-30.

Metz TD, McMillin GA, Silver RM, Allshouse AA, Heard K, Jensen TL, Wymore EM, Stickrath E, Conageski C, Kinney GL, Binswanger IA. Quantification of Prenatal Marijuana Use: Evaluation of the Correlation between Self-Report, Serum, Urine and Umbilical Cord Assays among Women Delivering at Two Urban Colorado Hospitals. Addiction 2022;117(1):172-181.

Layfield LJ, Yang Z, Vazmitsel M, Zhang T, Esebua M, Schmidt R. The international system for serous fluid cytopathology: Interobserver agreement. Diagnostic Cytopathology 2022;50(1):3-7.

Kulasingam V, Booth RA, Peterson LK, Snyder MR. The Journal of Applied Laboratory Medicine Special Issue on Autoimmune Diagnostics. Journal of Applied Laboratory Medicine 2022;7(1):1-2.

Wang Z, Zhe S, Zimmerman J, Morrisey C, Tonna JE, Sharma V, Metcalf RA. Development and validation of a machine learning method to predict intraoperative red blood cell transfusions in cardiothoracic surgery. Scientific Reports 2022;12(1):1355.

Leung ML, Ji J, Baker S, Buchan JG, Sivakumaran TA, Krock BL, Hutchins R, Bayrak-Toydemir P, Pfeifer J, Cremona ML, Funke B, Santani AB. A Framework of Critical Considerations in Clinical Exome Reanalyses by Clinical and Laboratory Standards Institute. The Journal of Molecular Diagnostics 2022;24(2):177-188.

Li P, White T, Xie W, Cui W, Peker D, Zeng G, Wang HY, Vagher J, Brown S, Williams M, Kovacsovics T, Patel JL. AML with germline DDX41 variants is a clinicopathologically distinct entity with an indolent clinical course and favorable outcome. Leukemia 2022;36(3):664-674.

Bajaj AO, Kushnir MM, Kish-Trier E, Law RN, Zuromski L, Molinelli AR, McMillin GA, Johnson-Davis KL. LC-MS/MS method for measurement of Thiopurine Nucleotides (TN) in erythrocytes and association of TN concentrations with TPMT enzyme activity. Frontiers in Pharmacology 2022;13:836812.

Bajaj AO, Slechta ES, Barker AP. Rapid and Accurate Differentiation of Mycobacteroides abscessus Complex Species by Liquid Chromatography-Ultra-High-Resolution Orbitrap™ Mass Spectrometry. Frontiers in Cellular and Infection Microbiology 2022;12:809348.

Stevenson JB. 12.2.2 Use of Controls and Calibrators. Clinical Microbiology Procedures Handbook, 5th Edition. ASM Press, Washington, DC 2022;

Simpson SJ, Lim MY, George TI, Rets A. 36-year-old male with X-linked congenital sideroblastic anemia presenting as chronic microcytic anemia with iron overload. International Journal of Laboratory Hematology 2022;44(1):69-71.

Min S, Shoda T, Wen T, Rothenberg ME. Diagnostic Merits of Eosinophilic Esophagitis Diagnostic Panel from a Single Esophageal Biopsy. The Journal of Allergy and Clinical Immunology 2022;149(2):782-787.

Anderson J, Putnam E, Liu W, Menon MP. Discovery of G6PD deficiency in a patient with DUSP22-rearranged ALK-negative anaplastic large cell lymphoma in leukemic phase. International Journal of Laboratory Hematology 2022;44(1):67-68.

Jawad M, Afkhami M, Ding Y, Zhang X, Li P, Young K, Xu ML, Cui W, Zhao Y, Halene S, Al-Kali A, Viswanatha D, Chen D, He R, Zheng G. DNMT3A R882 Mutations Confer Unique Clinicopathologic Features in MDS Including a High Risk of AML Transformation. Frontiers in Oncology 2022;12:849376.

Gonzales PR, Andersen EF, Brown TR, Horner VL, Horwitz J, Rehder CW, Rudy NL, Robin NH, Thorland EC, On Behalf Of The ACMG Laboratory Quality Assurance Committee. Interpretation and reporting of large regions of homozygosity and suspected consanguinity/uniparental disomy, 2021 revision: A technical standard of the American College of Medical Genetics and Genomics (ACMG). Genetics in Medicine 2022;24(2):255-261.

Wang H, Zhang J, Kao C, Budvytiene I, Ho DY, Mathison B, Hogan CA. Answer to April 2022 Photo Quiz. Journal of Clinical Microbiology 2022;60(4):e0124721.

Nicholas TJ, Al-Sweel N, Farrell A, Mao R, Bayrak-Toydemir P, Miller CE, Bentley D, Palmquist R, Moore B, Hernandez EJ, Cormier MJ, Fredrickson E, Noble K, Rynearson S, Holt C, Karren MA, Bonkowsky JL, Tristani-Firouzi M, Yandell M, Marth G, Quinlan AR, Brunelli L, Toydemir RM, Shayota BJ, Carey JC, Boyden SE, Malone Jenkins S. Comprehensive variant calling from whole-genome sequencing identifies a complex inversion that disrupts ZFPM2 in familial congenital diaphragmatic hernia. Molecular Genetics and Genomic Medicine 2022;10(4):e1888.

Mathison MA, Pritt BS. Encyclopedia of Infection and Immunity: Parasites of the Ear. Reference Module in Biomedical Sciences 2022;3(2022):279-286.

Mathison BA, Pritt BS. Encyclopedia of Infection and Immunity: Parasites of the Gastrointestinal Tract. Reference Module in Biomedical Sciences 2022;3(2022);136-203.

Klamroth R, Hayes G, Andreeva T, Gregg K, Suzuki T, Mitha IH, Hardesty B, Shima M, Pollock T, Slev P, Oldenburg J, Ozelo MC, Stieltjes N, Castet SM, Mahlangu J, Peyvandi F, Kazmi R, Schved JF, Leavitt AD, Callaghan M, Pan-Petesch B, Quon DV, Andrews J, Trinh A, Li M, Wong WY. Global seroprevalence of pre-existing immunity against AAV5 and other AAV serotypes in people with hemophilia A. Human Gene Therapy 2022;33(7-8):432-441.

Menos A, Mathison B, Pritt B, Lamps LW, Pai SA. Intramural Ova of Enterobius vermicularis in the Appendix-An Egg-Topic Location! International Journal of Surgical Pathology 2022;30(2):214-216.

Wang H, Zhang J, Kao C, Budvytiene I, Ho DY, Mathison B, Hogan CA. Photo Quiz: A 25-Year-Old Man with Hematuria and a Bladder Nodule. Journal of Clinical Microbiology 2022;60(4):e0124621.

Bajaj AO, Ly D, Johnson-Davis KL. Retrospective analysis of metabolite patterns of clobazam and N-desmethylclobazam in human plasma by LC-MS/MS. Journal of Mass Spectrometry and Advances in the Clinical Lab 2022;24:100-106.

Mathison BA, Pritt BS. Amebic colitis. Pathology Outlines. 2022.

Shoda T, Collins MH, Rochman M, Wen T, Caldwell JM, Mack LE, Osswald GA, Besse JA, Haberman Y, Aceves SS, Arva NC, Capocelli KE, Chehade M, Davis CM, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Khoury P, Klion A, Menard-Katcher C, Leung J, Mukkada V, Putnam PE, Spergel JM, Wechsler JB, Yang GY, Furuta GT, Denson LA, Rothenberg ME; Consortium of Eosinophilic Gastrointestinal Diseases Researchers (CEGIR). Evaluating Eosinophilic Colitis as a Unique Disease using Colonic Molecular Profiles: A Multi-Site Study. Gastroenterology 2022;162(6):1635-1649.

Nandakumar V, Profaizer T, Lozier BK, Elgort MG, Rychert J, Slev PR, Delgado JC. Evaluation of a Novel Multiplex Platform for Simultaneous Detection of IgG Antibodies against the Four Main SARS-CoV-2 Antigens. Journal of Applied Laboratory Medicine 2022;7(3):698-710.

Kanack AJ, Singh B, George G, Gundabolu K, Koepsell SA, Abou-Ismail MY, Moser KA, Smock KJ, Green D, Major A, Chan CW, Wool GD, Reding M, Ashrani A, Bayas A, Grill DE, Padmanabhan A. Persistence of Ad26.COV2.S-associated vaccine-induced immune thrombotic thrombocytopenia (VITT) and specific detection of VITT antibodies. American Journal of Hematology 2022;97(5):519-526.