The Institute for Clinical and Experimental Research® is focused on the development of new diagnostic assays in a wide range of disciplines. Researchers at the institute regularly publish in respected, peer-reviewed journals, give presentations at national and international organizations, author books and book chapters, and develop new tests.

Publications by Year

2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020

Recent Publications

Bystrom C, Grant RP, Bachmann LM, DeMarco M, Holmes DT, Hoofnagle AN, Intelmann D, Jeffery D, Kushnir MM, Ladwig P, Lowenthal MS, Master SR, Shuford CM, Thomas S, Whiteaker J. C64 Quantitative Measurement of Proteins and Peptides by Mass Spectrometry. 1st ed. Clinical and Laboratory Standards Institute 2021.

Penell JC, Kushnir MM, Lind L, Bergquist J, Bergquist J, Lind PM, Naessen T. Concentrations of Nine Endogenous Steroid Hormones in 70-Year Old Men and Women. Endocrine Connections 2021;10(5), 511-520.

Knight V, Askar MZ, Ntrivalas E, Nandiwada SL, Peterson LK, Tebo AE, Kadkhoda K, Schmitz JL, Naides SJ, Snyder MR, Sadighi Akha AA. Highlights of the 33rd annual scientific meeting of the Association of Medical Laboratory Immunologists (AMLI). Journal of Immunological Methods 2021;492:112994.

Kim SJ, Song J, Reading NS, Lautersztain J, Kutlar A, Agarwal AM, Coetzer TL, Prchal JT. Novel Mechanism of Hereditary Pyropoikilocytosis Phenotype due to Co-inheritance of B Globin and α Spectrin Mutations. American Journal of Hematology 2021;96(5):E150-E154.

Mathison BA, Pritt BS. Chapter 77: Amebiasis. Netter's Infectious Diseases, 2nd Edition 2021;454-459.

Gong B, Li D, Kusko R, Novoradovskaya N, Zhang Y, Wang S, Pabón-Peña C, Zhang Z, Lai K, Cai W, LoCoco JS, Lader E, Richmond TA, Mittal VK, Liu LC, Johann DJ Jr, Willey JC, Bushel PR, Yu Y, Xu C, Chen G, Burgess D, Cawley S, Giorda K, Haseley N, Qiu F, Wilkins K, Arib H, Attwooll C, Babson K, Bao L, Bao W, Lucas AB, Best H, Bhandari A, Bisgin H, Blackburn J, Blomquist TM, Boardman L, Burgher B, Butler DJ, Chang CJ, Chaubey A, Chen T, Chierici M, Chin CR, Close D, Conroy J, Coleman JC, Craig DJ, Crawford E, Del Pozo A, Deveson IW, Duncan D, Eterovic AK, Fan X, Foox J, Furlanello C, Ghosal A, Glenn S, Guan M, Haag C, Hang X, Happe S, Hennigan B, Hipp J, Hong H, Horvath K, Hu J, Hung LY, Jarosz M, Kerkhof J, Kipp B, Kreil DP, Łabaj P, Lapunzina P, Li P, Li QZ, Li W, Li Z, Liang Y, Liu S, Liu Z, Ma C, Marella N, Martín-Arenas R, Megherbi DB, Meng Q, Mieczkowski PA, Morrison T, Muzny D, Ning B, Parsons BL, Paweletz CP, Pirooznia M, Qu W, Raymond A, Rindler P, Ringler R, Sadikovic B, Scherer A, Schulze E, Sebra R, Shaknovich R, Shi Q, Shi T, Silla-Castro JC, Smith M, López MS, Song P, Stetson D, Strahl M, Stuart A, Supplee J, Szankasi P, Tan H, Tang LY, Tao Y, Thakkar S, Thierry-Mieg D, Thierry-Mieg J, Thodima VJ, Thomas D, Tichý B, Tom N, Garcia EV, Verma S, Walker K, Wang C, Wang J, Wang Y, Wen Z, Wirta V, Wu L, Xiao C, Xiao W, Xu S, Yang M, Ying J, Yip SH, Zhang G, Zhang S, Zhao M, Zheng Y, Zhou X, Mason CE, Mercer T, Tong W, Shi L, Jones W, Xu J. Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions. Genome Biology 2021;22(1):109.​

​Turner K, Raber H, Hansen S, Tran A, Gurgle H. Effects of 5 Dynamics on stu​dent perception of team performance. Currents in Pharmacy Teaching & Learning 2021;13(4):438-442.

​Moore RA, Schmidt RL, Metcalf RA. In reply: Window periods for secondary bacterial culture of platelets according to FDA guidance. Transfusion 2021;61(4):1343-1344.

​Bergan S, Brunet M, Hesselink DA, Johnson-Davis KL, Kunicki PK, Lemaitre F, Marquet P, Molinaro M, Noceti O, Pattanaik S, Pawinski T, Seger C, Shipkova M, Swen JJ, van Gelder T, Venkataramanan R, Wieland E, Woillard JB, Zwart TC, Barten MJ, Budde K, Dieterlen MT, Elens L, Haufroid V, Masuda S, Millan O, Mizuno T, Moes DJAR, Oellerich M, Picard N, Salzmann L, Tönshoff B, van Schaik RHN, Vethe NT, Vinks AA, Wallemacq P, Åsberg A, Langman LJ. Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology. Therapeutic Drug Monitoring 2021;43(2):150-200.

​Mathison BA, Couturier MR. Laboratory diagnosis of amebiasis and intestinal amebae. College of American Pathologists, Continuing Education P-A 2021.​

Swami U, Haaland B, Kessel A, Nussenzveig R, Maughan BL, Esther J, Sirohi D, Pal SK, Grivas P, Agarwal N. Comparative Effectiveness of Immune Checkpoint Inhibitors in Patients with Platinum-Refractory Advanced Urothelial Carcinoma. The Journal of Urology 2021;205(3):709-717.

​Kroft SH, Sever CE, Bagg A, Billman B, Diefenbach C, Dorfman DM, Finn WG, Gratzinger DA, Gregg PA, Leonard JP, Smith S, Souter L, Weiss RL, Ventura CB, Cheung MC. Laboratory Workup of Lymphoma in Adults: Guideline From the American Society for Clinical Pathology and the College of American​ Pathologists. Archives of Pathology & Laboratory Medicine 2021;145(3):269-290.

​Humphries RM, Azar MM, Caliendo AM, Chou A, Colgrove RC, Fabre V, Ginocchio CC, Hanson KE, Hayden MK, Pillai DR, Pollock NR, Lee FM. To Test, Perchance to Diagnose: Practical Strategies for Severe Acute Respiratory Syndrome Coronavirus 2 Testing. Open Forum Infectious Diseases 2021;8(4):ofab095.​

Doyle K​. Commentary on Extreme Hyperglycemia in an Elderly Patient. Clinical Chemistry 2021;67(5):729.

Wyness SP, Genzen JR. Performance evaluation of five lipoprotein(a) immunoassays on the Roche cobas c501 chemistry analyzer. Practical Laboratory Medicine 2021;25:e00218.

Bernard PS, Wooderchak-Donahue W, Wei M, Bray SM, Wood KC, Parikh B, McMillin G. Potential Utility of Pre-Emptive Germline Pharmacogenetics in Breast Cancer.Cancers 2021;13(6):1219​.

Lin L, Carlquist J, Sinclair W, Hall T, Lopansri BK, Bennett ST​.Experience with False Positive Test Results on the TaqPath Real-Time Reverse Transcription-PCR COVID-19 Testing Platform.Archives of Pathology & Laboratory Medicine 2021;145(3):259-261.​

Jackson BR, Ye Y, Crawford JM, Becich MJ, Roy S, Botkin JR, de Baca ME, Pantanowitz L.The Ethics of Artificial Intelligence in Pathology and Laboratory Medicine: Principles and Practice.Academic Pathology 2021;8:2374289521990784.

​Kushnir MM, Straseski JA.What can we Learn from a Sensitive and Specific Measurements of Parathyroid Hormone-related Peptide (PTHrP)?AACC Academy's Scientific Shorts 2021;Online.

Christensen KD, Bell M, Zawatsky CLB, Galbraith LN, Green RC, Hutchinson AM, Jamal L, LeBlanc JL, Leonhard JR, Moore M, Mullineaux L, Petry N, Platt DM, Shaaban S, Schultz A, Tucker BD, Van Heukelom J, Wheeler E, Zoltick ES, Hajek C; Imagenetics MetricsTeam.Precision Population Medicine in Primary Care: The Sanford Chip Experience. Frontiers in Genetics 2021;12:626845.

Nelson RS, Seligson ND, Bottiglieri S, Carballido E, Cueto AD, Imanirad I, Levine R, Parker AS, Swain SM, Tillman EM, Hicks JK​.UGT1A1 Guided Cancer Therapy: Review of the Evidence and Considerations for Clinical Implementation. Cancers (Basel) 2021;13(7):1566.

Ng DP, Zuromski LM​.Augmented Human Intelligence and Automated Diagnosis in Flow Cytometry for Hematologic Malignancies.American Journal of Clinical Pathology 2021;155:597-605.​

Liou TG, Adler FR, Cahill BC, Cox DR, Cox JE, Grant GJ, Hanson KE, Hartsell SC, Hatton ND, Helms MN, Jensen JL, Kartsonaki C, Li Y, Leung DT, Marvin JE, Middleton EA, Osburn-Staker SM, Packer KA, Shakir SM, Sturrock AB, Tardif KD, Warren KJ, Waddoups LJ, Weaver LJ, Zimmerman E, Paine R 3rd. SARS-CoV-2 innate effector associations and viral load in early nasopharyngeal infection. Physiological Reports 2021;9(4):e14761.

Tebo AE, Schmidt RL, Kadkhoda K, Peterson LK, Chan EKL, Fritzler MJ, Wener MH. The antinuclear antibody HEp-2 indirect immunofluorescence assay: a survey of laboratory performance, pattern recognition and interpretation. Auto-Immunity Highlights 2021;12(1):4.

Velappan N, Close D, Hung LW, Naranjo L, Hemez C, DeVore N, McCullough DK, Lillo AM, Waldo GS, Bradbury ARM. Construction, characterization and crystal structure of a fluorescent single-chain Fv chimera. Protein Engineering, Design & Selection 2021;34:gzaa029.

Zhou XA, Yang J, Ringbloom KG, Martinez-Escala ME, Stevenson KE, Wenzel AT, Fantini D, Martin HK, Moy AP, Morgan EA, Harkins S, Paxton CN, Hong B, Andersen EF, Guitart J, Weinstock DM, Cerroni L, Choi J, Louissaint A, Jr. Genomic landscape of cutaneous follicular lymphomas reveals 2 subgroups with clinically predictive molecular features. Blood Advances 2021;5(3):649-661.

Pitel BA, Sharma N, Zepeda-Mendoza C, Smadbeck JB, Pearce KE, Cook JM, Vasmatzis G, Sachs Z, Kanagal-Shamanna R, Viswanatha D, Xiao S, Jenkins RB, Xu X, Hoppman NL, Ketterling RP, Peterson JF, Greipp PT, Baughn LB. Myeloid malignancies with 5q and 7q deletions are associated with extreme genomic complexity, biallelic TP53 variants, and very poor prognosis. Blood Cancer Journal 2021;11(2):18.

Bajaj AO, Kushnir MM, Kish-Trier E, McMillin GA, Johnson-Davis KL. Automated separation and washing of red blood cells (RBCs) from whole blood.IP.com 2021;PCOM000264613D.

Mathison BA, Bradbury RS, Pritt BS. Medical Parasitology Taxonomy Update, January 2018-May 2020.Journal ofClinicalMicrobiology 2021;59 (2) e01308-20.

Zheng Y, Larragoite ET, Williams ESCP, Lama J, Cisneros I, Delgado JC, Slev P, Rychert J, Innis EA, Coiras M, Rondina MT, Spivak AM, Planelles V. Neutralization assay with SARS-CoV-1 and SARS-CoV-2 spike pseudotyped murine leukemia virions.Virology Journal 2021;18(1):1.

Jackson BR, Genzen JR. The Lab Must Go On.American Journal of Clinical Pathology 2021;155(1):4-11.

Smy L, De Biase I, Genzen JR, Yuzyuk T. The Nuclear Magnetic Resonance Metabolic Profile: Impact of Fasting Status.Clinical Biochemistry 2021;87:85-92.

Bajaj AO, Saraswat S, Knuuttila JEA, Freeke J, Stielow JB, Barker AP. Accurate Identification of Closely Related Mycobacterium tuberculosis Complex Species by High Resolution Tandem Mass Spectrometry. Frontiers in Cellular and Infection Microbiology 2021;11:656880.

Mathison BA, Pritt BS. Chapter 65: Medical Parasitology. pp. 1290-1351 In: McPherson RA, Pincus MR (eds.). Henry’s Clinical Diagnosis and Management by Laboratory Methods, 24th ed. Philadelphia, PA: Elsevier. 2021.

Liu BM, Martins TB, Peterson LK, Hill HR. Clinical significance of measuring serum cytokine levels as inflammatory biomarkers in adult and pediatric COVID-19 cases: A review. Cytokine 2021;142:155478.

Liu BM, Carlisle CP, Fisher MA, Shakir SM. Closing the Brief Case: Capnocytophaga sputigena Bacteremia in a 94-Year-Old Male with Type 2 Diabetes Mellitus, Pancytopenia, and Bronchopneumonia. Journal of Clinical Microbiology 2021;59(7):e0247320.

Sobczyk J, Pyne MT, Barker A, Mayer J, Hanson KE, Samore MH, Noriega R. Efficient and effective single-step screening of individual samples for SARS-CoV-2 RNA using multi-dimensional pooling and Bayesian inference. Journal of the Royal Society, Interface 2021;18(179):20210155.

Patel JL, Abedi M, Cogle CR, Erba HP, Foucar K, Garcia-Manero G, Grinblatt DL, Komrokji RS, Kurtin SE, Maciejewski JP, Pollyea DA, Revicki DA, Roboz GJ, Savona MR, Scott BL, Sekeres MA, Steensma DP, Thompson MA, Dawn Flick E, Kiselev P, Louis CU, Nifenecker M, Swern AS, George TI. Real-world diagnostic testing patterns for assessment of ring sideroblasts and SF3B1 mutations in patients with newly diagnosed lower-risk myelodysplastic syndromes. International Journal of Laboratory Hematology 2021;43(3):426-432.

Liu BM, Carlisle CP, Fisher MA, Shakir SM. The Brief Case: Capnocytophaga sputigena Bacteremia in a 94-Year-Old Male with Type 2 Diabetes Mellitus, Pancytopenia, and Bronchopneumonia. Journal of Clinical Microbiology 2021;59(7):e0247220.

Zhou W, Rowe L, Witt B, Deftereos G. Application of the Roche cobas® HPV 4800 in formalin-fixed, paraffin-embedded samples for head and neck squamous cell carcinomas. Head and Neck Pathology 2021;15(2):532-536.

Sirdah M, Reading N, Vankayalapati H, Prchal J. A computational study of structural differences of binding of NAD and G6P substrates to G6PD Mediterraneanc.563T, G6PD A-c.202A/c.376G, G6PD Cairoc.404C and G6PD Gazac.536A mutations. Blood Cells, Molecules and Diseases 2021;89:102572.

Smock KJ. ADAMTS13 testing update: Focus on laboratory aspects of difficult thrombotic thrombocytopenic purpura diagnoses and effects of new therapies. International Journal of Laboratory Hematology 2021;43 Suppl 1:103-108.

Pedersen BS, Brown JM, Dashnow H, Wallace AD, Velinder M, Tristani-Firouzi M, Schiffman JD, Tvrdik T, Mao R, Best DH, Bayrak-Toydemir P, Quinlan AR. Effective variant filtering and expected candidate variant yield in studies of rare human disease. NPJ Genomic Medicine 2021;6(1):60.

Agarwal AM, Rets A. Laboratory approach to investigation of anemia in pregnancy. International Journal of Laboratory Hematology 2021;43 Suppl 1:65-70.

Lai J, Garvey KY, Li P, Azevedo RA. Primary ovarian melanoma arising from a mature teratoma with melanoma in situ present in the ciliated columnar and squamous epithelium in a patient with synchronous skin basal cell carcinoma. International Journal of Gynecological Pathology 2021;40(4):383-390.

Kroner GM, Yuzyuk TN, Zuromski L, Johnson LM. Retrospective comparison of results for simultaneous orders for LDL particle count, apolipoprotein B, and LDL-C. 2021;518:38-42.

Mathew Thomas V, Gilreath JA, Newton S, Smock KJ, Lim MY. Daratumumab as a novel treatment for refractory acquired von Willebrand syndrome associated with monoclonal gammopathy. Haemophilia 2021;27(4):e563-e566.

Sharma A, Greene DN, Chambliss AB, Farnsworth CW, French D, Herman DS, Kavsak PA, Merrill AE, Margaret Lo SY, Lyon ME, Winston-McPherson G, Pearson LN, SoRelle JA, Waring AC, Schmidt RL. The effect of the Covid-19 shutdown on glycemic testing and control. Clinica Chimica Acta 2021; 519:148-152.

Profaizer T, Dibb K, Bethers H, Monds C, Andreasen J, Delgado JC, Lázár-Molnár E. Comparison of Next-Generation Sequencing-Based Human Leukocyte Antigen Typing with Clinical Flow Cytometry and Allele-Specific PCR Melting Assays for HLA-B27 Genotyping. The Journal of Applied Laboratory Medicine 2021;6(5):1221-1227.

Williams JP, Abbatemarco JR, Galli JJ, Rodenbeck SJ, Peterson LK, Haven TR, Street M, Rose JW, Greenlee JE, Mateo Paz Soldan M, Clardy SL. Aquaporin-4 Autoantibody Detection by ELISA: A Retrospective Characterization of a Commonly Used Assay. Multiple Sclerosis International 2021; vol. 2021, Article ID 8692328, 6 pages.

Mathison BA, Pritt BS. Cyclosporiasis - updates on clinical presentation, pathology, clinical diagnosis, and treatment. Microorganisms 2021;9:1863.

Lozier BK, Haven TR, Tebo AE, Peterson LK. Performance evaluation of a radioimmunoprecipitation assay for the detection of N-type voltage-gated calcium channel antibodies. Journal of Immunological Methods 2021; 496:113102.