This page centralizes all information regarding our annual and biweekly CPT code updates to American Medical Association Current Procedural Terminology (CPT) codes. Annual and biweekly updates are available for download, and the biweekly are also listed in the table below. If you would like to receive an email notification when updates have been added to this page, click on the subscribe button below.

CPT codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based on AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.


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Annual CPT Code Updates

This section contains annual changes to the AMA's CPT codes assigned to tests, which are released around the 15th of December.

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Download PDF of annual CPT changes


Biweekly CPT Code Updates

This section lists changes to the AMA’s CPT codes assigned to tests, which are updated on or near the 1st and 15th of each month.

Download spreadsheet of biweekly CPT code changes
Download PDF of biweekly CPT code changes

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Effective Date Test Number Test Name CPT Code(s)
1/2/2024 3001255 Prion Markers (CJD), CSF 86317; 0035U
1/2/2024 3017170 Narcolepsy HLA-DQ Genotyping (HLA-DQB1*06:02) 81382
1/1/2024 0080009 Acetylcholine Receptor Binding Antibody 86041
1/1/2024 0099521 Acetylcholine Receptor Modulating Antibody 86043
1/1/2024 0099580 Acetylcholine Receptor Blocking Antibody 86042
1/1/2024 2001571 Acetylcholine Receptor Antibody Reflexive Panel 86041; 86042; if reflexed, add 86043
1/1/2024 2002656 Anti-Mullerian Hormone 82166
1/1/2024 2005639 Acetylcholine Receptor Antibodies and Striated Muscle Antibodies Reflexive Panels, and Titin Antibody 86041; 86042; 83516; 86255; if reflexed, add 86043; 86256
1/1/2024 2013881 Hepatitis Delta Virus by Quantitative PCR 87523
1/1/2024 3001868 Acetylcholine Receptor Binding Antibody with reflex to Muscle-Specific Kinase (MuSK) Ab, IgG 86041; if reflexed, add 86366; 86256
1/1/2024 3001869 Myasthenia Gravis Reflexive Panel 86041; 86042; if reflexed, add 86043; 86366; 86256
1/1/2024 3002581 Vaginitis Panel by TMA 81513; 87481 x2; 87661
1/1/2024 3002583 Candida glabrata, Candida species, and Trichomonas vaginalis by TMA 87481 x2; 87661
1/1/2024 3003017 Autoimmune Neuromuscular Junction Reflexive Panel 83519 x2; 83516; 86041; 86042; 86255; 86596 x2; if reflexed, add 86043; 86255 x2; 86256 x3
1/1/2024 3006051 Autoimmune Neurologic Disease Panel with Reflex, Serum 83519 x2; 84182 x2; 86255 x12; 86341; 86052; 86362; 86596; if reflexed, add 84182 x4; 86041; 86256
1/1/2024 3006198 Muscle-Specific Kinase (MuSK) Antibody, IgG by CBA-IFA with Reflex to Titer, Serum 86366; if reflexed, add 86256
1/1/2024 3006379 Hepatitis Delta Virus Antibody by ELISA With Reflex to Hepatitis Delta Virus by Quantitative PCR 86692; if reflexed, add 87523
12/18/2023 3017046 Allergen, Food, Sesame Seed Component rSes i 1 86008
12/18/2023 3017049 Allergen, Food, Sesame Seed With Reflex to Component, IgE 86003; if reflexed add 86008
12/4/2023 3017098 Microbial Cell-Free DNA by Sequencing (Karius Test) 0152U
12/4/2023 3017103 Mutated Citrullinated Vimentin (MCV) Antibody, Serum 83520
11/14/2023 3016940 Strongyloides Culture and Identification, Fecal 87081; If detected, add 87177
11/14/2023 3016976 Strongyloides Identification, Fecal Bill 87177
11/13/2023 3016760 Borrelia burgdorferi VlsE1/pepC10 Antibodies, CSF, Total by ELISA With Reflex to IgM and IgG by Immunoblot (Standard Two-Tier Testing, CSF) 86618; if reflexed, add 86617 x2
11/13/2023 3016761 Borrelia burgdorferi Antibodies, IgG and IgM by Immunoblot (CSF) Reflex 86617 x2
11/13/2023 3016794 Recoverin Antibody, IgG by Immunoblot, Serum 84182
11/13/2023 3016795 Histoplasma and Blastomyces by PCR 87798 x2
11/13/2023 3016801 CY 88121G Bladder Cancer FISH 88121
11/13/2023 3016804 Autoimmune Vision Loss Panel, Serum 84182, 86255; if reflexed, add 86256
11/13/2023 3016817 Celiac Disease Reflexive Cascade, Serum 86364; if reflexed additional CPT codes may apply: 86364, 86231; 86258 x2
11/13/2023 3016839 JAK2 (V617F) Mutation by ddPCR, Qualitative With Reflex to CALR (Calreticulin) Exon 9 Mutation Analysis by PCR and MPL Mutation Detection 81270; if reflexed add 81219 and 81338
11/13/2023 3016840 JAK2 (V617F) Mutation by ddPCR, Qualitative With Reflex to JAK2 Exon 12 Mutation Analysis by PCR 81270; if reflexed, add 81279
11/13/2023 3016853 Myelin Oligodendrocyte Glycoprotein (MOG) Antibody, IgG by CBA-IFA With Reflex to Titer, CSF 86362; if reflexed, add 86256
11/13/2023 3016856 Myelin Oligodendrocyte Glycoprotein (MOG) Antibody Titer, IgG, CSF (Reflex of 3016853 MOG CSF - Not orderable by clients) 86256
11/13/2023 3016858 von Willebrand Factor (VWF) Collagen III Binding 0279U
11/13/2023 3016860 Tissue Transglutaminase Antibody, IgA 86364
11/13/2023 3016861 Tissue Transglutaminase Antibody, IgA With Reflex to Endomysial Antibody, IgA by IFA 86364; if reflexed, add 86231
11/13/2023 3016866 Cortisol by LC-MS/MS, Salivary 82533
11/13/2023 3016875 Twin Zygosity 81265
11/13/2023 3016908 Huntington Disease (HD) CAG Repeat Expansion 81271
11/13/2023 3016920 5-Hydroxyindoleacetic Acid (HIAA), Plasma 83497
11/13/2023 3016927 Factor 13, Qualitative, With Reflex to Factor 13 1:1 Mix 85291; if reflexed, add 85291
11/13/2023 3016928 Factor 13 1:1 Mix 85291
11/1/2023 3016966 Antibody Screen RBC, DTT 86850, 86970
10/23/2023 3016621 Myeloid Malignancies Mutation and Copy Number Variation Panel by Next Generation Sequencing 81455
10/11/2023 3016943 Human Papillomavirus (HPV) High Risk Screen, by Transcription-Mediated Amplification (TMA), ThinPrep 87624
10/11/2023 3016944 Human Papillomavirus (HPV) Genotypes 16 and 18/45, by Transcription-Mediated Amplification (TMA), ThinPrep 87625
10/11/2023 3016945 Human Papillomavirus (HPV) High Risk Screen by Transcription-Mediated Amplification (TMA), with Reflex to Genotypes 16 and 18/45, ThinPrep 87624; if reflexed, add 87625
10/2/2023 3016932 Vitamin B7, Serum or Plasma 84591
9/27/2023 3016767 Anti-Phospholipase A2 Receptor (PLA2R) Antibody, IgG by ELISA 83516
9/26/2023 3016815 Candida auris Surveillance Culture Culture: 87102, Identification: Varies based on method.
9/11/2023 3016879 CD30 for Bone Marrow Specimens by Immunohistochemistry 88342
9/5/2023 3016813 Pepsin A, Respiratory 83986, 84157, 83516
9/5/2023 3016847 Herpes Simplex Virus Type 1 and 2 Antibodies, IgG by Western Blot, Serum 86695, 86696
8/28/2023 3016788 OLIG2 by Immunohistochemistry 88342
8/22/2023 3016782 SSTR2 by Immunohistochemistry 88342
8/21/2023 3001591 Comprehensive Epilepsy Panel, Sequencing and Deletion/Duplication 81419
8/21/2023 3004583 Drug Detection Panel, Meconium, Qualitative 80326; 80347; 80364; 80355; 80323 (Alt code: G0481)
8/21/2023 3006366 Pharmacogenetics Panel: Psychotropics, with GeneDose Access 81225; 81226; 81227; 81230; 81231; 81291; 81479; if reflexed, add 81479
8/21/2023 3006373 Drug Detection Panel and THC Metabolite, Meconium, Qualitative 80326; 80347; 80364; 80355; 80349; 80323 (Alt code: G0481)
8/21/2023 3016503 Thiopurine Metabolites in Red Blood Cells 80299 (Alt code: G0480)
8/21/2023 3016579 Beta-hCG, Quantitative (Pregnancy) 84702
8/21/2023 3016583 Exome Sequencing 81415: per familial comparator, 81416 is added
8/21/2023 3016589 Exome Sequencing, Familial Control NA
8/21/2023 3016598 Body Fluid, Creatinine 82570
8/21/2023 3016604 CSF, Total Protein 84157
8/21/2023 3016614 CSF, Glucose 82945
8/21/2023 3016616 Hemoglobin S Evaluation with Reflex to RBC Solubility 83021; if reflexed, add 85660
8/21/2023 3016632 Cyclic Citrullinated Peptide Antibody, IgG and IgA 86200
8/21/2023 3016634 Rheumatoid Arthritis (RA) Panel 86200; 86431; 83516
8/21/2023 3016635 Rheumatoid Arthritis (RA) Panel with Reflex to Rheumatoid Factors, IgA, IgG, and IgM by ELISA 86200; 86431; 83516 if reflexed, add 83516 x3
8/21/2023 3016639 Red Blood Cell Antigen Genotyping, Fetal 0001U; 81265 Fetal Cell Contamination (FCC)
8/21/2023 3016640 RhD Gene (RHD) Copy Number, Fetal 81403; 81265 Fetal Cell Contamination (FCC)
8/21/2023 3016646 Urine, Amylase 82150
8/21/2023 3016649 Urine, Glucose 82945
8/21/2023 3016654 Acute Myeloid Leukemia Panel by FISH 88271 x7; 88275 x7
8/21/2023 3016673 Platelet Antigen Genotyping Panel, Fetal 81105; 81106; 81107; 81108; 81109; 81110; 81112; 81265 Fetal Cell Contamination (FCC)
8/21/2023 3016676 Kell K/k (KEL) Antigen Genotyping, Fetal 0001U; 81265 Fetal Cell Contamination (FCC)
8/21/2023 3016679 RhC/c (RHCE) Antigen Genotyping, Fetal 0001U; 81265 Fetal Cell Contamination (FCC)
8/21/2023 3016682 RhE/e (RHCE) Antigen Genotyping, Fetal 0001U; 81265 Fetal Cell Contamination (FCC)
8/21/2023 3016687 Coccidioides by PCR 87798
8/14/2023 3016567 INSM1 by Immunohistochemistry 88342
8/7/2023 3016752 Vitamin B3 (Niacin and Metabolites), Serum/Plasma 84591
8/7/2023 3016769 Anti-Dense Fine Speckled 70 (DFS70) Antibody by ELISA, Serum 86038
7/17/2023 3016533 Envoplakin Antibody, IgG by ELISA 83516
7/17/2023 3016534 Paraneoplastic Pemphigus (Paraneoplastic Autoimmune Multiorgan Syndrome) Expanded Antibody Panel by IIF With ELISA 88346; 88350 x3; 83516
7/10/2023 3016552 CD103 by Immunohistochemistry 88342
7/10/2023 3016561 Annexin A1 by Immunohistochemistry 88342
7/7/2023 3000959 AAV5 Detect CDxTM -AAV5 Total Antibody Assay for ROCTAVIAN (valoctocogene roxaparvovec-rvox) Eligibility in Hemophilia A  
7/6/2023 3016457 Pneumonia Panel by PCR 87633
6/26/2023 3006379 Hepatitis Delta Virus Antibody by ELISA With Reflex to Hepatitis Delta Virus by Quantitative PCR 86692; if reflexed, add 87799
6/26/2023 3016631 HBV Exposure Panel 86706; 86704; 87340; if reflexed, add 87341
6/20/2023 3016694 Trypsin, Serum 83519
6/12/2023 3016493 Whole Genome Sequencing 81425; per familial comparator, 81426 is added
6/12/2023 3016493 Whole Genome Sequencing 81425; per familial comparator, 81426 is added
5/23/2023 3006357 NR4A3 Rearrangement by FISH 88366
5/22/2023 3006344 Mycoplasmoides genitalium Detection and Macrolide Resistance by PCR 87798, 87563
5/22/2023 3006367 Tickborne Disease Antibodies Panel 86753; 86666 x2; 86618; if reflexed, add 86617 x2
5/15/2023 3001868 Acetylcholine Receptor Binding Antibody with reflex to Muscle-Specific Kinase (MuSK) Ab, IgG 83519; if reflexed, add 86255; if reflexed, add 86256
5/15/2023 3001869 Myasthenia Gravis Reflexive Panel 83519; 83516; if reflexed, add 83516 or 86255; if reflexed, add 86256
5/15/2023 3005949 Aldosterone and Renin Direct, With Ratio Refer to Aldosterone (0070015) and Renin, Direct (2001575)
5/15/2023 3006198 Muscle-Specific Kinase (MuSK) Antibody, IgG by CBA-IFA with Reflex to Titer, Serum 86255; if reflexed, add 86256
5/15/2023 3006201 Autoimmune Encephalopathy/Dementia Panel, Serum 86341; 84182 x2; 86255 x10; if reflexed, add 84182 x4; 86256 per titer
5/15/2023 3006202 Autoimmune Encephalopathy/Dementia Panel, CSF 86341; 84182 x2; 86255 x10; if reflexed, add 84182 x4; 86256 per titer
5/15/2023 3006203 Autoimmune Dysautonomia Panel, Serum 83519; 86255 x5; if reflexed, add 84182; 86256 per titer
5/15/2023 3006204 Autoimmune Epilepsy Panel, Serum 86341; 84182 x2; 86255 x10; if reflexed, add 84182 x4; 86256 per titer
5/15/2023 3006205 Autoimmune Epilepsy Panel, CSF 86341; 84182 x2; 86255 x10; if reflexed, add 84182 x4; 86256 per titer
5/15/2023 3006206 Autoimmune Movement Disorder Panel, Serum 86341; 86596; 84182 x2; 86255 x12; if reflexed, add 84182 x4; 86256 per titer
5/15/2023 3006207 Autoimmune Movement Disorder Panel, CSF 86341; 84182 x2; 86255 x12; if reflexed, add 84182 x4; 86256 per titer
5/15/2023 3006208 Autoimmune Myelopathy Panel, Serum 86341; 86362; 86052; 84182 x2; 86255 x5; if reflexed, add 84182 x4; 86256 per titer
5/15/2023 3006209 Autoimmune Myelopathy Panel, CSF 86341; 86052; 84182 x2; 86255 x5; if reflexed, add 84182 x4; 86256 per titer
5/15/2023 3006210 Autoimmune Pediatric CNS Disorders, Serum 86341; 86362; 86052; 86255 x8; if reflexed, add 84182 x2; 86256 per titer
5/15/2023 3006211 Autoimmune Pediatric CNS Disorders, CSF 86341; 86052; 86255 x8; if reflexed, add 84182 x2; 86256 per titer
5/15/2023 3006234 Autoimmune Stiff-Person Disorders, Serum 86341; 84182; 86255; if reflexed, add 86256
5/15/2023 3006235 Autoimmune Stiff-Person Disorders, CSF 86341; 84182; 86255; if reflexed, add 86256
5/15/2023 3006247 Angelman Syndrome and Prader-Willi Syndrome by Methylation-Specific MLPA 81331; for fetal specimens add 81265
5/15/2023 3006297 Luteinizing Hormone by Immunohistochemistry 88342
5/15/2023 3006300 Follicle Stimulating Hormone by Immunohistochemistry 88342
5/15/2023 3006343 Prenatal Hepatitis Panel 87340; 86803; if reflexed, add 87341; 87522
5/15/2023 3006371 Drug Detection Panel and THC Metabolite, Umbilical Cord Tissue, Qualitative 80326; 80347; 80364; 80355; 80349 (Alt code: G0481)
5/15/2023 3006373 Drug Detection Panel and THC Metabolite, Meconium, Qualitative 80326; 80347; 80364; 80355; 80349 (Alt code: G0481)
5/15/2023 3006383 Prolonged Clot Time Reflexive Profile 85390-26; additional CPT codes may apply: 85210; 85220; 85230; 85240; 85245; 85246; 85250; 85260; 85270; 85280; 85335; 85379; 85384; 85385; 85525; 85597; 85598; 85610; 85611; 85613; 85635; 85670; 85730; 85732
5/11/2023 3002638 SARS-CoV-2 (COVID-19) by NAA 87635
5/1/2023 3006254 JC Virus Antibody by ELISA, Serum with Reflex to Inhibition Assay 86711; if reflexed, add 86711
5/1/2023 3016444 Phospho-Tau/Total-Tau/A Beta42, CSF 83520 x3
4/24/2023 3006149 BRAF by Immunohistochemistry 88342
4/24/2023 3006162 IRF8 by Immunohistochemistry 88342
4/24/2023 3006370 Candida auris by PCR 87481
4/18/2023 3006351 Cathepsin K by Immunohistochemistry 88342
4/3/2023 3006271 Helicobacter pylori, Breath Test 83013
3/28/2023 3006178 Isobutyryl/butyryl-carnitine (C4) Quantitative, Urine 82017
3/27/2023 3006053 Borrelia burgdorferi VlsE1/pepC10 Antibodies, Total by ELISA With Reflex to IgM and IgG by ELISA (Modified Two-Tier Testing) 86618; if reflexed, add 86618 x2
3/20/2023 3005674 Genital Ulcer Disease Panel by PCR 87491, 87529 x2, 87798 x2
3/15/2023 3005939 Rapid Whole Genome Reanalysis 81427
3/7/2023 2002290 Chromosome Analysis, Leukemic Blood 88237; 88264; for COG studies, add 88299
3/7/2023 2002292 Chromosome Analysis, Bone Marrow 88237; 88264; for COG studies, add 88299
3/7/2023 2007130 Chromosome Analysis, Bone Marrow with Reflex to Genomic Microarray 88237; 88264; if reflexed, add 81277; for COG studies, add 88299
3/7/2023 2007131 Chromosome Analysis, Leukemic Blood with Reflex to Genomic Microarray 88237; 88264; if reflexed, add 81277; for COG studies, add 88299
3/6/2023 3006285 Adiponectin Quantitative, Serum/Plasma 83520
2/28/2023 3006242 Mycobacterium Tuberculosis by Immunohistochemistry 88342
2/27/2023 3005935 Rapid Whole Genome Sequencing 81425; per familial comparator, 81426 is added
2/27/2023 3005939 Rapid Whole Genome Reanalysis 81417
2/21/2023 3000477 Hypersensitivity Pneumonitis Panel 86331 x5; 86606 x5
2/21/2023 3001561 Hypersensitivity Pneumonitis Extended Panel (Farmer's Lung Panel) 86003 x3; 86005; 86331 x5; 86606 x5
2/21/2023 3001633 Hereditary Central Nervous System Cancer Panel, Sequencing and Deletion/Duplication 81201; 81203; 81403; 81404; 81405; 81406; 81407; 81408; 81479
2/21/2023 3002673 Hereditary Melanoma Panel, Sequencing and Deletion/Duplication 81167; 81216; 81404; 81321; 81323; 81351; 81479
2/21/2023 3005912 Hereditary Paraganglioma-Pheochromocytoma Expanded Panel, Sequencing and Deletion/Duplication 81437; 81438
2/21/2023 3005944 Hereditary Thyroid Cancer Panel, Sequencing and Deletion/Duplication 81201; 81203; 81404; 81405; 81321; 81323; 81406; 81351; 81479
2/21/2023 3005960 Complement C5, Functional 86161
2/21/2023 3005961 C5 Inhibitors Drug Monitoring Panel 86160; 86161 x2; 86162
2/21/2023 3005963 Hereditary Gastric Cancer Panel, Sequencing and Deletion/Duplication 81201; 81203; 81292; 81294; 81295; 81297; 81298; 81300; 81317; 81319; 81403
2/21/2023 3005976 Free Thyroxine Index Panel 84479; 84436
2/21/2023 3005977 T Uptake 84479
2/21/2023 3005978 Thyroxine, Total T4 84436
2/21/2023 3005996 Triglycerides Body Fluid with Reflex to Chylomicron Electrophoresis 84478; if reflexed, add 82664
2/21/2023 3006003 Gamma-Aminobutyric Acid Receptor, Type A (GABA-AR) Antibody, IgG by CBA-IFA with Reflex to Titer, CSF 86255; if reflexed, add 86256
2/21/2023 3006008 Gamma-Aminobutyric Acid Receptor, Type A (GABA-AR) Antibody, IgG by CBA-IFA with Reflex to Titer, Serum 86255; if reflexed, add 86256
2/21/2023 3006013 IgLON Family Member 5 (IgLON5) Antibody, IgG by CBA-IFA With Reflex to Titer, CSF 86255; if reflexed, add 86256
2/21/2023 3006018 IgLON Family Member 5 (IgLON5) Antibody, IgG by CBA-IFA With Reflex to Titer, Serum 86255; if reflexed, add 86256
2/21/2023 3006023 Inositol 1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Antibody, IgG by CBA-IFA With Reflex to Titer, CSF 86255; if reflexed, add 86256
2/21/2023 3006031 Inositol 1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Antibody, IgG by CBA-IFA With Reflex to Titer, Serum 86255; if reflexed, add 86256
2/21/2023 3006039 Metabotropic Glutamate Receptor 1 (mGluR1) Antibody, IgG by CBA-IFA With Reflex to Titer, CSF 86255; if reflexed, add 86256
2/21/2023 3006044 Metabotropic Glutamate Receptor 1 (mGluR1) Antibody, IgG by CBA-IFA With Reflex to Titer, Serum 86255; if reflexed, add 86256
2/21/2023 3006049 Autoimmune Encephalitis Reflex Panel, CSF 86052; 86255 x9; 83519; 86341; if reflexed, add 86256 per titer.
2/21/2023 3006050 Autoimmune Encephalitis Extended Panel, Serum 83519; 86052; 86341; 86362; 86255 x9; if reflexed, add 86256 per titer.
2/21/2023 3006051 Autoimmune Neurologic Disease Panel with Reflex, Serum 83519 x2; 84182 x2; 86255 x12; 86341; 86052; 86362; 86596; if reflexed, add 83519; 84182 x4; 86256 per titer
2/21/2023 3006052 Autoimmune Neurologic Disease Panel With Reflex, CSF 86255 x12; 83519; 86341; 84182 x2; if reflexed, add 84182 x4; 86256 per titer
2/21/2023 3006065 Hypersensitivity Pneumonitis 1 86331 x3; 86606 x2
2/21/2023 3006066 Toxocara Antibodies, IgG by ELISA 86682
2/21/2023 3006075 BK Virus by Quantitative NAAT, Urine 87799
2/21/2023 3006076 BK Virus by Quantitative NAAT, Plasma 87799
2/21/2023 3006079 Epstein-Barr Virus by Quantitative NAAT, Plasma 87799
2/21/2023 3006168 Thyroid Stimulating Hormone by Immunohistochemistry 88342
2/6/2023 2013484 TP53 Somatic Mutation, Prognostic 81352
2/6/2023 3005983 Merkel Cell Carcinoma Antibodies 0058U
2/1/2023 2005003 Paroxysmal Nocturnal Hemoglobinuria, High Sensitivity, WBC 86356 x4
2/1/2023 2005006 Paroxysmal Nocturnal Hemoglobinuria (PNH), High Sensitivity, RBC and WBC 86356 x6
1/1/2023 0092066 Thiopurine Methyltransferase, RBC 84433
1/1/2023 2007862 Ehrlichia and Anaplasma Species by PCR 87468; 87484; 87798 x2
1/1/2023 2008665 Babesia Species by PCR 87469; 87798
1/1/2023 2008670 Tick-Borne Disease Panel by PCR, Blood 87468; 87484; 87798 x3; 87469
12/20/2022 3006111 ST2, Soluble 83006
12/9/2022 3005393 Chimerism, Posttransplant, Sorted Cells (T Cells) 81268
12/9/2022 3005401 Chimerism, Posttransplant, Sorted Cells (B Cells) 81268
12/9/2022 3005409 Chimerism, Posttransplant, Sorted Cells (CD33+ Cells) 81268
12/9/2022 3005417 Chimerism, Posttransplant, Sorted Cells (Granulocytes) 81268
12/9/2022 3005425 Chimerism, Posttransplant, Sorted Cells (Monocytes) 81268
12/9/2022 3005433 Chimerism, Posttransplant, Sorted Cells (CD34+ Cells) 81268
12/9/2022 3005441 Chimerism, Posttransplant, Sorted Cells (CD 56+ Cells) 81268
12/5/2022 3005941 Histoplasma Galactomannan Antigen by EIA, Quantitative, Body Fluid 87385
12/5/2022 3005956 MGMT Promoter Methylation Detection by ddPCR 81287
11/15/2022 3005900 PHOX2B by Immunohistochemistry 88342
11/14/2022 0040248 KRAS Mutation Detection 81275; 81276
11/14/2022 0051415 Ashkenazi Jewish Diseases, 16 Genes 81401; 81209; 81200; 81260; 81242; 81251; 81250; 81479; 81205; 81290; 81400; 81330; 81255
11/14/2022 0051750 BRAF Codon 600 Mutation Detection with Reflex to MLH1 Promoter Methylation 81210; If reflexed, add 81288
11/14/2022 2002327 Mismatch Repair by Immunohistochemistry with Reflex to BRAF Codon 600 Mutation and MLH1 Promoter Methylation 88342; 88341 x3; if reflexed, add 81210; if further reflexed, add 81288
11/14/2022 2002440 EGFR Mutation Detection by Pyrosequencing 81235
11/14/2022 2002498 BRAF Codon 600 Mutation Detection by Pyrosequencing 81210
11/14/2022 2003123 NRAS Mutation Detection by Pyrosequencing 81311
11/14/2022 2005270 Mismatch Repair by Immunohistochemistry with Reflex to MLH1 Promoter Methylation 88342; 88341 x3; if reflexed, add 81288
11/14/2022 2008863 Holoprosencephaly Panel, Sequencing and Deletion/Duplication, Fetal 81479; 81265
11/14/2022 2009310 MGMT Promoter Methylation Detection (Change effective as of 12/05/2022: Refer to 3005956 in the December Hotline) 81287
11/14/2022 2010769 Noonan Spectrum Disorders Panel, Sequencing, Fetal 81442; 81265
11/14/2022 2012010 Skeletal Dysplasia Panel, Sequencing and Deletion/Duplication, Fetal 81405; 81408; 81479; 81265
11/14/2022 3000894 Hereditary Hemolytic Anemia Cascade 84220; 88184; 82955; 83021. Reflex components billed separately. Additional CPT codes may apply, 85555; 85060; 85007; 83068; 81269; 81259; 81363; 81364; 81249; 81443; 85660; 83020; 81479
11/14/2022 3001615 Hereditary Bone Marrow Failure Panel, Sequencing and Deletion/Duplication 81443; for skin punch biopsy, add 88233
11/14/2022 3002096 Tuberous Sclerosis Complex Panel, Sequencing and Deletion/Duplication, Fetal 81405; 81406; 81407; 81265
11/14/2022 3002134 IDH1 R132H Point Mutation by Immunohistochemistry with Reflex to IDH1 and IDH2 Mutation Analysis, Exon 4 88342; if reflexed, add 81120; 81121
11/14/2022 3002135 1p19q Deletion by FISH and IDH1 R132H Point Mutation by Immunohistochemistry with Reflex to IDH1 and IDH2 Mutation Analysis, Exon 4 88342; 88377 x2; if reflexed, add 81120; 81121
11/14/2022 3004267 IDH1 and IDH2 Mutation Analysis Exon 4, Formalin-Fixed, Paraffin-Embedded (FFPE) Tissue 81120; 81121
11/14/2022 3004273 Cytogenomic Molecular Inversion Probe Array FFPE Tissue - Products of Conception 81229
11/14/2022 3004275 Cytogenomic Molecular Inversion Probe Array FFPE Tissue - Oncology 81277
11/14/2022 3004277 Microsatellite Instability (MSI) HNPCC/Lynch Syndrome by PCR 81301
11/14/2022 3004279 Gastrointestinal Stromal Tumor Mutations 81272; 81314
11/14/2022 3004283 KIT Mutations Melanoma 81272; 81314
11/14/2022 3004294 Solid Tumor Mutation Panel, Sequencing 81445
11/14/2022 3004308 MLH1 Promoter Methylation 81288
11/14/2022 3005632 Hereditary Breast Cancer High-Risk Panel, Sequencing and Deletion/Duplication 81162; 81406; 81307; 81321; 81323; 81351; 81479
11/14/2022 3005654 Hereditary Breast Cancer Guidelines-Based Panel, Sequencing and Deletion/Duplication 81408; 81479; 81162; 81406; 81307; 81321; 81323; 81404; 81405; 81351
11/14/2022 3005686 Hereditary Prostate Cancer Panel, Sequencing and Deletion/Duplication 81408; 81162; 81403; 81292; 81294; 81295; 81297; 81298; 81300; 81307; 81317; 81319; 81351; 81479
11/14/2022 3005696 Hereditary Retinoblastoma (RB1) Sequencing and Deletion/Duplication 81479
11/14/2022 3005697 Hereditary Gastrointestinal Cancer High-Risk Panel, Sequencing and Deletion/Duplication 81201; 81203; 81292; 81294; 81295; 81297; 81298; 81300; 81406; 81317; 81319; 81479
11/14/2022 3005703 Birt-Hogg-Dube Syndrome (FLCN) Sequencing and Deletion/Duplication 81479
11/14/2022 3005708 Hereditary Pancreatic Cancer Panel, Sequencing and Deletion/Duplication 81201; 81203; 81408; 81162; 81292; 81294; 81295; 81297; 81298; 81300; 81307; 81317; 81319; 81404; 81405; 81351; 81403; 81479
11/14/2022 3005714 DNA Extract and Hold N/A
11/14/2022 3005721 Hereditary Erythrocytosis Panel, Sequencing 81364, 81404; 81479; for skin punch biopsy, add 88233
11/14/2022 3005839 Diagnostic Qualitative BCR-ABL1 Assay with Reflex to p190 or p210 Quantitative Assays 81206; 81207; 81208; If reflexed, add 81206 or 81207
11/14/2022 3005840 Quantitative Detection of BCR-ABL1, Major Form (p210) 81206
11/14/2022 3005859 Sertraline, Serum or Plasma 80332 (Alt code: G0480)
11/14/2022 3005860 Trazodone, Serum/Plasma 80338 (Alt code: G0480)
11/14/2022 3005863 Transforming Growth Factor beta1, Plasma 83520
11/14/2022 3005865 Transforming Growth Factor beta1, Serum 83520
11/14/2022 3005867 Familial Targeted Sequencing 81403
11/14/2022 3005869 Familial Targeted Sequencing, Fetal 81403; 81265 Fetal Cell Contamination (FCC)
11/14/2022 3005874 Kratom, Umbilical Cord, Qual 80323 (Alt code: G0480)
11/14/2022 3005882 Dysautonomia, Familial (ELP1), 2 Variants 81260
11/14/2022 3005895 Cytomegalovirus by Quantitative NAAT, Plasma 87497
11/8/2022 3004508 Cytomegalovirus Drug Resistance by Next Generation Sequencing, Ganciclovir, Foscarnet, Cidofovir, and Maribavir 87910; 87900
11/8/2022 3004509 Cytomegalovirus Drug Resistance by Next Generation Sequencing, Letermovir 87910; 87900
11/8/2022 3004615 Cytomegalovirus Drug Resistance by Next Generation Sequencing, Ganciclovir, Foscarnet, Cidofovir, Maribavir, and Letermovir 87910; 87900
11/7/2022 3005925 Ustekinumab Quantitation with Antibodies, Serum 80299; 83520
10/25/2022 3005916 CIC (19q13.2) Gene Rearrangement by FISH 88366
10/14/2022 3004833 Drug Profile, Expanded Targeted Panel by LC-MS/MS, Serum/Plasma 80323; 80326; 80329; 80334; 80337; 80338; 80341; 80344; 80346; 80348; 80353; 80354; 80356; 80357; 80358; 80359; 80360; 80361; 80363; 80365; 80366; 80368; 80370; 80371; 80372; 80373; 80377; 83992 (Alt code: G0482)
08/31/2022 0060280 Herpes Simplex Virus DFA with Reflex to Herpes Simplex Virus Culture 87274; 87273; if reflexed, add 87255
08/31/2022 0060283 Varicella-Zoster Virus and Herpes Simplex Virus DFA with Reflex to Varicella-Zoster Virus Culture and Herpes Simplex Virus Culture 87290; 87274; 87273; if reflexed, add 87252; 87254; 87255
08/31/2022 2013684 PD-L1 28-8 pharmDx by Immunohistochemistry with Interpretation, nivolumab (OPDIVO) 88360
08/15/2022 0051415 Ashkenazi Jewish Diseases, 16 Genes 81401; 81209; 81200; 81260; 81242; 81251; 81250; 81479; 81205; 81290; 81400; 81330; 81255
08/15/2022 0065005 Herpes Simplex Virus Culture 87255
08/15/2022 0065065 Herpes Simplex Virus Culture with Reflex to HSV Typing 87255; if reflexed, add 87140 x2
08/15/2022 2006540 Aortopathy Panel, Sequencing and Deletion/Duplication 81410; 81411
08/15/2022 2007384 Vascular Malformations Panel, Sequencing and Deletion/Duplication 81321; 81323; 81405; 81406; 81479
08/15/2022 2008848 Holoprosencephaly Panel, Sequencing and Deletion/Duplication 81479
08/15/2022 2008863 Holoprosencephaly Panel, Sequencing and Deletion/Duplication, Fetal 81479; 81265 Fetal Cell Contamination (FCC)
08/15/2022 2009337 Hereditary Hemorrhagic Telangiectasia (HHT) Panel, Sequencing and Deletion/Duplication 81405; 81406; 81479
08/15/2022 2009345 Pulmonary Arterial Hypertension (PAH) Panel, Sequencing and Deletion/Duplication 81405; 81406; 81479
08/15/2022 2010183 Cardiomyopathy and Arrhythmia Panel, Sequencing and Deletion/Duplication 81403; 81404; 81405; 81406; 81407; 81408; 81479; 81414
08/15/2022 2010214 Hereditary Renal Cancer Panel, Sequencing and Deletion/Duplication 81292; 81294; 81295; 81297; 81298; 81300; 81317; 81319; 81321; 81323; 81351
08/15/2022 2011156 Primary Antibody Deficiency Panel, Sequencing and Deletion/Duplication 81403; 81404; 81405; 81406; 81408; 81479
08/15/2022 2011157 Cobalamin/Propionate/Homocysteine Metabolism Related Disorders Panel, Sequencing and Deletion/Duplication 81404; 81405; 81406; 81479
08/15/2022 2012010 Skeletal Dysplasia Panel, Sequencing and Deletion/Duplication, Fetal 81405; 81408; 81479; 81265 Fetal Cell Contamination (FCC)
08/15/2022 2012015 Skeletal Dysplasia Panel, Sequencing and Deletion/Duplication 81405; 81408; 81479
08/15/2022 2012026 Hereditary Breast and Gynecological Cancers Panel, Sequencing and Deletion/Duplication 81432; 81433
08/15/2022 2012032 Hereditary Cancer Panel, Sequencing and Deletion/Duplication 81432; 81433; 81435; 81436; 81437; 81438
08/15/2022 2013449 Hereditary Gastrointestinal Cancer Panel, Sequencing and Deletion/Duplication 81435; 81436
08/15/2022 3001513 CYP2D6 81226; if reflexed, add 81479
08/15/2022 3001524 Cytochrome P450 Genotyping Panel 81225; 81226; 81227; 81230; 81231; 81479; if reflexed, add 81479
08/15/2022 3001603 Long QT Panel, Sequencing and Deletion/Duplication 81403; 81404; 81406; 81407; 81414; 81479
08/15/2022 3002096 Tuberous Sclerosis Complex Panel, Sequencing and Deletion/Duplication, Fetal 81405; 81406; 81407; 81265
08/15/2022 3002100 Tuberous Sclerosis Complex Panel, Sequencing and Deletion/Duplication 81405; 81406; 81407
08/15/2022 3002286 Cerebral Cavernous Malformation Panel, Sequencing and Deletion/Duplication 81479
08/15/2022 3004255 Cytochrome P450 Genotyping Panel, with GeneDose Access 81225; 81226; 81227; 81230; 81231; 81479; if reflexed, add 81479
08/15/2022 3004471 Pharmacogenetics Panel: Psychotropics 81225; 81226; 81227; 81230; 81231; 81291; 81479; if reflexed, add 81479
08/15/2022 3004764 Fetal Aneuploidy Screening 81420
08/15/2022 3004778 Fetal Aneuploidy Screening with 22q11.2 Microdeletion 81420; 81422
08/15/2022 3004781 Fetal Aneuploidy Screening with Microdeletions 81420; 81422
08/15/2022 3004833 Drug Profile, Expanded Targeted Panel by LC-MS/MS, Serum/Plasma 80323; 80325; 80329; 80334; 80337; 80338; 80341; 80344; 80347; 80348; 80353; 80354; 80355; 80356; 80357; 80359; 80360; 80361; 80363; 80365; 80366; 80368; 80370; 80371; 80372; 80373; 80377; 83992 (Alt code: G0482)
08/15/2022 3005060 Drug Profile, Expanded Targeted Panel by LC-MS/MS, Urine 80323; 80325; 80329; 80334; 80337; 80338; 80341; 80344; 80347; 80348; 80353; 80354; 80355; 80356; 80357; 80359; 80360; 80361; 80363; 80365; 80366; 80368; 80370; 80371; 80372; 80373; 80377; 83992 (Alt code: G0482)
08/15/2022 3005393 Chimerism, Posttransplant, Sorted Cells (T Cells) 81268; 88184
08/15/2022 3005401 Chimerism, Posttransplant, Sorted Cells (B Cells) 81268; 88184
08/15/2022 3005409 Chimerism, Posttransplant, Sorted Cells (CD33+ Cells) 81268; 88184
08/15/2022 3005417 Chimerism, Posttransplant, Sorted Cells (Granulocytes) 81268; 88184
08/15/2022 3005425 Chimerism, Posttransplant, Sorted Cells (Monocytes) 81268; 88184; 88185
08/15/2022 3005433 Chimerism, Posttransplant, Sorted Cells (CD34+ Cells) 81268; 88184; 88185
08/15/2022 3005441 Chimerism, Posttransplant, Sorted Cells (CD 56+ Cells) 81268; 88184; 88185
08/15/2022 3005449 Chimerism, Recipient, Pretransplant 81265
08/15/2022 3005454 Chimerism, Posttransplant 81267
08/15/2022 3005462 Chimerism, Donor See CPT codes under Chimerism, Recipient, Pretransplant (3005449)
08/15/2022 3005468 Chimerism, Additional Donor 81266
08/15/2022 3005478 Glomerular Filtration Rate (Estimated) 82565
07/26/2022 3005716 Orthopoxvirus (includes monkeypox virus) by PCR 87593
07/25/2022 3005716 Orthopoxvirus (includes monkeypox virus) by PCR 87798
07/05/2022 0092399 HIV PhenoSense GT 87900; 87901; 87903; 87904 x12
07/05/2022 3000882 Human Immunodeficiency Virus Type 1 (HIV-1) PhenoSense 87903; 87904 x12
07/05/2022 3002787 Autoimmune Encephalitis Reflexive Panel, CSF 86052; 86255 x6; 83519; 86341; if reflexed, add 86256 per titer
07/05/2022 3003680 MET Exon 14 Deletion Analysis by PCR 81479
07/05/2022 3003684 NTRK Fusion Panel by Next Generation Sequencing 81194
07/05/2022 3005636 Hypoglycemia Panel (Sulfonylureas), Serum or Plasma 80377 (Alt Code: G0480)
06/29/2022 3005593 Claudin-4 by Immunohistochemistry 88342
06/06/2022 0065080 Bordetella pertussis/parapertussis by PCR 87798 x2
06/06/2022 2004963 Malaria Species Identification by PCR 87798 x5
06/06/2022 2007862 Ehrlichia and Anaplasma Species by PCR 87798 x4
06/06/2022 2008665 Babesia Species by PCR 87798 x2
06/06/2022 2008670 Tick-Borne Disease Panel by PCR, Blood 87798 x6
06/06/2022 2010095 Herpes Simplex Virus (HSV-1/HSV-2) Subtype by PCR 87529 x2
06/06/2022 2011148 Herpes Simplex Virus (HSV) by PCR with Reflex to HSV (HSV-1/HSV-2) Subtype by PCR 87529; if reflexed, add 87529 x2
06/06/2022 2011172 Urogenital Ureaplasma and Mycoplasma Species by PCR 87798 x3; 87563
06/06/2022 2011626 Microsporidia by PCR 87798 x2
06/06/2022 2011660 Gastrointestinal Parasite and Microsporidia by PCR 87505; 87798 x2
06/06/2022 2013294 Dengue Virus (1-4) Subtype by PCR 87798 x4
06/06/2022 2013798 Candida Species by PCR 87481 x5
06/06/2022 2014546 Norovirus, Groups 1 and 2 by PCR 87798 x2
06/06/2022 3000265 Aspergillus Species by PCR 87798 x2
06/06/2022 3000876 Aspergillus fumigatus Antibody IgG 86317
05/23/2022 3003043 Non-Invasive Prenatal Aneuploidy Screen by cell-free DNA Sequencing 81420
05/18/2022 3005011 H3.3 G34W Mutant by Immunohistochemistry 88342
05/16/2022 3000894 Hereditary Hemolytic Anemia Cascade 84220; 88184; 82955; 83021 If reflexed additional CPT codes may apply; refer to the reflexed test code for applicable codes
05/16/2022 3001605 Lynch Syndrome Panel, Sequencing and Deletion/Duplication 81292; 81294; 81295; 81297; 81298; 81300; 81317; 81319; 81403
05/16/2022 3004430 Circulating Immune Complex Panel 86332 x2
05/16/2022 3004431 Circulating Immune Complex, C3 fragments 86332
05/16/2022 3004531 Familial Transthyretin Amyloidosis (TTR) Sequencing 81404
05/16/2022 3004547 Beta Globin (HBB) Sequencing 81364
05/16/2022 3004550 Beta Globin (HBB) Sequencing, Fetal 81364; 81265 Fetal Cell Contamination (FCC)
05/16/2022 3004572 Multiple Endocrine Neoplasia Type 2 (MEN2), RET Sequencing 81406
05/16/2022 3004583 Drug Detection Panel, Meconium, Qualitative 80326; 80347; 80364; 80355 (Alt code: G0481)
05/16/2022 3004603 SHOX Deficiency Disorders, Sequencing and Deletion/Duplication 81405; 81479
05/16/2022 3004716 Galactosemia (GALT) Sequencing and Deletion/Duplication 81406; 81479
05/16/2022 3004720 Connexin 26 (GJB2) Sequencing and Deletion/Duplication 81252; 81479
05/16/2022 3004745 Cystic Fibrosis (CFTR) Sequencing and Deletion/Duplication 81222; 81223
05/16/2022 3004753 Allergen, Food, Nut Component Panel IgE 86008 x6
05/16/2022 3004788 Pancreatitis Panel (CFTR, CTRC, PRSS1, SPINK1), Sequencing 81223; 81404; 81405
05/02/2022 3004978 Brivaracetam Quantitative, Serum or Plasma 80375 (Alt Code: G0480)
05/02/2022 3005003 Matrix Metalloproteinase-9 (MMP-9) 83520
05/02/2022 3005200 Legionella pneumophila Antibodies (Types 1-6), IgG, IgM, and IgA by ELISA 86713
04/20/2022 3004827 BCOR by Immunohistochemistry 88342
04/12/2022 3004813 Phosphorylated TDP43 by Immunohistochemistry 88342
04/04/2022 2007370 Periodic Fever Syndromes Panel, Sequencing and Deletion/Duplication 81404; 81479
03/29/2022 3004609 Breast Carcinoma Dual Stain by Immunohistochemistry 88344
03/29/2022 3004795 CD22 by Immunohistochemistry 88342
03/22/2022 3004727 SATB2 by Immunohistochemistry 88342
03/07/2022 3002337 2,3 Dinor-11Beta-Prostaglandin F2 Alpha, 24-Hour Urine 84150
03/07/2022 3002351 Leukotriene E4, Random Urine 82542; 82570
03/07/2022 3004792 Leukotriene E4, 24-Hour Urine 82542
03/01/2022 3001784 Interstitial Lung Disease Autoantibody Panel 86235 x5; 83516 x7; 84182 x2; 86431; 86200; 86039
02/22/2022 2010841 Paraneoplastic Antibodies (PCCA/ANNA) by IFA with Reflex to Titer and Immunoblot, CSF 86255; if reflexed, add 84182 x4 and/or 86256
02/22/2022 3002787 Autoimmune Encephalitis Reflexive Panel, CSF 86052; 86255 x6; 83519; 86341; if reflexed, add 86256 per titer
02/22/2022 3002887 Autoimmune Neurologic Disease Reflexive Panel, CSF 86255 x8; 83519; 86341; 84182 x2; if reflexed, add 84182 x4; 86256 per titer
02/22/2022 3004310 CYP2B6 81479
02/22/2022 3004379 von Willebrand Disease (VWF) Sequencing 81408
02/22/2022 3004383 Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy, CADASIL (NOTCH3), Sequencing 81406
02/22/2022 3004386 UGT1A1 Sequencing 81404
02/22/2022 3004407 APC- and MUTYH-Associated Polyposis Panel, Sequencing and Deletion/Duplication 81201; 81203; 81406; 81479
02/22/2022 3004411 Wilson Disease (ATP7B) Sequencing 81406
02/22/2022 3004419 Very Long-Chain Acyl-CoA Dehydrogenase Deficiency (ACADVL) Sequencing and Deletion/Duplication 81406; 81479
02/22/2022 3004424 Biotinidase Deficiency (BTD) Sequencing 81404
02/22/2022 3004434 Familial Mediterranean Fever (MEFV) Sequencing 81404
02/22/2022 3004437 Multiple Endocrine Neoplasia Type 1 (MEN1) Sequencing and Deletion/Duplication 81404; 81405
02/22/2022 3004457 Glucose-6-Phosphate Dehydrogenase Deficiency (G6PD) Sequencing 81249
02/22/2022 3004465 Celiac Antibodies, Tissue Transglutaminase (tTG), IgA and IgA, Total 82784; 86364
02/22/2022 3004472 Schistosoma Antibody IgG by ELISA 86682
02/22/2022 3004480 Hereditary Paraganglioma-Pheochromocytoma (SDHA, SDHB, SDHC, and SDHD) Sequencing and Deletion/Duplication 81404; 81405; 81406; 81479
02/22/2022 3004486 Tay-Sachs Disease (HEXA) Sequencing and Deletion/Duplication 81406; 81479
02/22/2022 3004510 Amphiphysin Antibody IgG, CSF 84182
02/22/2022 3004512 Dipeptidyl Aminopeptidase-Like Protein 6 (DPPX) Antibody, IgG by CBA-IFA With Reflex to Titer, CSF 86255; if reflexed, add 86256
02/22/2022 3004517 Paraneoplastic Reflexive Panel, CSF 86255 x2; 84182 x2; if reflexed, add 86256 and/or 84182 x4; if reflexed, add 86256
02/09/2022 2006621 Drug Detection Panel, Umbilical Cord Tissue, Qualitative 80326; 80347; 80364; 80355 (Alt code: G0481)
02/09/2022 2007479 Drug Profile, Targeted by Tandem Mass Spectrometry and Enzyme Immunoassay, Urine 80326; 80347; 80364; 80355; 80307 (Alt code: G0481)
02/09/2022 2009288 Drug Profile, Targeted with Interpretation by Tandem Mass Spectrometry and Enzyme Immunoassay, Urine 80326; 80347; 80364; 80355; 80307 (Alt code: G0481)
01/27/2022 3004541 Kappa Lambda Dual Stain by Immunohistochemistry 88344
01/18/2022 3004553 Stachybotrys chartarum/atra Panel 86001; 86003