This page centralizes all information regarding our annual and biweekly CPT code updates to American Medical Association Current Procedural Terminology (CPT) codes. Annual and biweekly updates are available for download, and the biweekly are also listed in the table below. If you would like to receive an email notification when updates have been added to this page, click on the subscribe button below.

CPT codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based on AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.

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Annual CPT Code Updates

This section contains annual changes to the AMA's CPT codes assigned to tests, which are released around the 15th of December.

Download spreadsheet of annual CPT changes
Download PDF of annual CPT changes

Biweekly CPT Code Updates

This section lists changes to the AMA’s CPT codes assigned to tests, which are updated on or near the 1st and 15th of each month.

Download spreadsheet of biweekly CPT code changes
Download PDF of biweekly CPT code changes

Effective DateTest NumberTest NameCPT Code(s)
9/3/202443018708Flucytosine by Mass Spectrometry, Serum/Plasma80375
8/28/20243018202Vasoactive Intestinal Polypeptide (VIP), Plasma84586
8/27/20243018046CD38 by Immunohistochemistry88342
8/27/20243018056p120 by Immunohistochemistry88342
8/27/20243018057MyoD1 by Immunohistochemistry88342
8/19/20243017744Antimicrobial Susceptibility - Helicobacter pylori87186
8/19/20243017747Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG (CSF) With Reflex to Type 1 and 2 Glycoprotein G-Specific Ab, IgG86694; if reflexed, add 86695; 86696
8/19/20243017749TORCH Antibodies IgM86645; 86762; 86778
8/19/20243017751Encephalitis Panel With Reflex to Herpes Simplex Virus Types 1 and 2 Glycoprotein G-Specific Antibodies, IgG, Serum86765 x2; 86735 x2; 86787 x2; 86789; 86788; 86694; if reflexed, add 86695; 86696
8/19/20243017752Encephalitis Panel With Reflex to Herpes Simplex Virus Types 1 and 2 Glycoprotein G-Specific Antibodies, IgG, CSF86765 x2; 86735 x2; 86787 x2; 86789; 86788; 86694; if reflexed, add 86695; 86696
8/19/20243017783CD42b by Immunohistochemistry88342
8/19/20243017866Dihydropyrimidine Dehydrogenase (DPYD) and UPD Glucuronosyltransferase 1A1 (UGT1A1) Genotyping81232; 81350
8/19/20243017909Preeclampsia Risk Assessment (sFlt-1/PlGF Ratio)83520 x2
8/19/20243017913Allergens, Food, Tree Nuts Profile IgE86003 x9
8/19/20243017914Allergens, Food, Fish Profile 2 IgE86003 x7
8/19/20243017915Allergens, Food, Crustacean Profile IgE86003 x4
8/19/20243017916Allergens, Food, Mollusks Profile IgE86003 x5
8/12/20243018558Allergen, Food, Walnut Component rJug r 1, IgE86008
8/12/20243018559Allergen, Food, Walnut (Juglans spp.) With Reflex to Components, IgE86003; if reflexed order 86008x2
8/12/20243018561Allergen, Food, Cashew Component rAna o 3, IgE86008
8/12/20243018562Allergen, Food, Cashew With Reflex to Components, IgE86003; if reflexed add 86008
7/25/20243017195Adiponectin, Quantitative Serum/Plasma83520
7/22/20242006621Drug Detection Panel, Umbilical Cord Tissue, Qualitative80346; 80348; 80353; 80361; 80356; 80365; 80373; 80354; 80363; 80355; 80359; 80325; 80345; 80372; 80358; 83992; 80368 (Alt code: G0482)
7/22/20243004583Drug Detection Panel, Meconium, Qualitative80346; 80348; 80353; 80361; 80356; 80365; 80373; 80354; 80362; 80355; 80359; 80325; 80360; 80345; 80372; 80358; 83992; 80323; 80368 (Alt code: G0482)
7/9/20243017828Mismatch Repair Panel by Immunohistochemistry88342/88341x3
5/20/20243017554QuantiFERON TB-Gold Plus, 1-Tube86480
5/20/20243017562QuantiFERON TB-Gold Plus, 4-Tube86480
5/20/20243017610RBC Antibody ID Package (IRL)86900; 86901; 86880; 86870 x3; additional CPT codes may apply
5/20/20243017611RBC Antibody ID Prenatal - Reflex to Titer86900; 86901; 86880; 86870; additional CPT codes may apply
5/20/20243017615PD-L1 22C3 by IHC88360
5/20/20243017653Alzheimer's Disease Markers, CSF83520 x3
5/3/20243017203BRAF Mutation Detection81210
5/3/20243017204BRAF Mutation Detection with Reflex to MLH1 Promoter Methylation81210; If reflexed, add 81288
5/3/20243017209Colorectal Cancer Mutation Panel81210, 81275, 81276, 81311
5/3/20243017222IDH1 and IDH2 Mutation Detection81120; 81121
5/3/20243017230Lung Cancer Mutation Panel81445, 81235, 81210, 81275, 81276
5/3/20243017233Melanoma Mutation Panel81210, 81272; 81275; 81276, 81311
5/3/20243017399TPSAB1 Copy Number Analysis by ddPCR81479
5/3/20243017549HLA-B51 Genotyping, Behcet Disease81381
5/3/20243017651Vitamin C, Plasma (High-Dose Therapy)82180
5/2/20243000414Human Papillomavirus (HPV) Genotype 16 and 18 by PCR, Head and Neck87625
4/15/20243017665Treponema pallidum, HSV-1 and HSV-2 by PCR87529 x2, 87798
4/2/20243016431B-Cell CD20 Expression by Flow Cytometry, Quantitative86355; 86356
4/1/20243017737Platelet Antibody Identification Panel86022
3/18/20243017050Rapid Acute Myeloid Leukemia Targeted Therapy Mutation Panel81450
3/18/20243017440Ma2/Ta Antibody, IgG by Immunoblot, CSF84182
3/18/20243017441Ma2/Ta Antibody, IgG by Immunoblot, Serum84182
3/5/20243017565Allergen, Food, Wheat Component rTri a 19 Omega 5-Gliadin, IgE86008
3/5/20243017569Allergen, Food, Wheat and nGliadin With Reflex to Components, IgE86003; 86008 if reflexed add 86008 x2
2/21/20243017372TPMT Genotyping81335
2/21/20243017373NUDT15 Genotyping81306
2/20/20243006383Prolonged Clot Time Reflexive Profile85390-26; additional CPT codes may apply: 85210; 85220; 85230; 85240; 85245; 85246; 85250; 85260; 85270; 85280; 85335; 85379; 85384; 85385; 85520; 85525; 85598; 85610; 85611; 85613; 85670; 85730; 85732.
2/20/20243016636HPV Primary Screen by PCR With Reflex to Cytology87624; if reflexed add 88142; if reviewed by pathologist add 88141
2/20/20243016779Infliximab and Antibodies to Infliximab Quantitation80230; 82397
2/20/20243016862Anti-Mullerian Hormone With Menopausal Status (MenoCheck)82166
2/20/20243016968Quantitative Detection of BCR-ABL1, Minor Form (p190)81207
2/20/20243016999CV2 Antibody, IgG by CBA-IFA With Reflex to Titer, Serum86255; if reflexed, add 86256
2/20/20243017001CV2 Antibody, IgG by CBA-IFA With Reflex to Titer, CSF86255; if reflexed, add 86256
2/20/20243017009Lupus Anticoagulant Reflex Panel85610; 85613; 85730; if reflexed, additional CPT codes may apply: 85520; 85525; 85598; 85613; 85670; 85730.
2/20/20243017043Adalimumab and Antibodies to Adalimumab Quantitation80145; 82397
2/20/20243017059Borrelia burgdorferi VlsE1/pepC10 Antibodies, Total by ELISA With Reflex to IgG and IgM by Immunoblot (Standard Two-Tier Testing)86618; if reflexed, add 86617 x2
2/20/20243017101Hemoglobin Evaluation With Reflex to Electrophoresis and/or RBC Solubility83021; if reflexed, add 83020; 85660
2/20/20243017156Thrombotic Risk Reflex Panel81240; 83090; 85300; 85303; 85306; 85307; 85610; 85613; 85730; 86147x2; 86146x2; if reflexed, additional CPT codes may apply: 81241; 85520; 85525; 85598; 85613; 85670; 85730.
2/20/20243017157Antiphospholipid Syndrome Reflex Panel85610; 85613; 85730; 86147x2; 86146x2; if reflexed, additional CPT codes may apply: 85520; 85525; 85598; 85613; 85670; 85730.
1/2/20243001255Prion Markers (CJD), CSF86317; 0035U
1/2/20243017170Narcolepsy HLA-DQ Genotyping (HLA-DQB1*06:02)81382
1/1/20240080009Acetylcholine Receptor Binding Antibody86041
1/1/20240099521Acetylcholine Receptor Modulating Antibody86043
1/1/20240099580Acetylcholine Receptor Blocking Antibody86042
1/1/20242001571Acetylcholine Receptor Antibody Reflexive Panel86041; 86042; if reflexed, add 86043
1/1/20242002656Anti-Mullerian Hormone82166
1/1/20242005639Acetylcholine Receptor Antibodies and Striated Muscle Antibodies Reflexive Panels, and Titin Antibody86041; 86042; 83516; 86255; if reflexed, add 86043; 86256
1/1/20242013881Hepatitis Delta Virus by Quantitative PCR87523
1/1/20243001868Acetylcholine Receptor Binding Antibody with reflex to Muscle-Specific Kinase (MuSK) Ab, IgG86041; if reflexed, add 86366; 86256
1/1/20243001869Myasthenia Gravis Reflexive Panel86041; 86042; if reflexed, add 86043; 86366; 86256
1/1/20243002581Vaginitis Panel by TMA81513; 87481 x2; 87661
1/1/20243002583Candida glabrata, Candida species, and Trichomonas vaginalis by TMA87481 x2; 87661
1/1/20243003017Autoimmune Neuromuscular Junction Reflexive Panel83519 x2; 83516; 86041; 86042; 86255; 86596 x2; if reflexed, add 86043; 86255 x2; 86256 x3
1/1/20243006051Autoimmune Neurologic Disease Panel with Reflex, Serum83519 x2; 84182 x2; 86255 x12; 86341; 86052; 86362; 86596; if reflexed, add 84182 x4; 86041; 86256
1/1/20243006198Muscle-Specific Kinase (MuSK) Antibody, IgG by CBA-IFA with Reflex to Titer, Serum86366; if reflexed, add 86256
1/1/20243006379Hepatitis Delta Virus Antibody by ELISA With Reflex to Hepatitis Delta Virus by Quantitative PCR86692; if reflexed, add 87523
12/18/20233017046Allergen, Food, Sesame Seed Component rSes i 186008
12/18/20233017049Allergen, Food, Sesame Seed With Reflex to Component, IgE86003; if reflexed add 86008
12/4/20233017098Microbial Cell-Free DNA by Sequencing (Karius Test)0152U
12/4/20233017103Mutated Citrullinated Vimentin (MCV) Antibody, Serum83520
11/14/20233016940Strongyloides Culture and Identification, Fecal87081; If detected, add 87177
11/14/20233016976Strongyloides Identification, Fecal Bill87177
11/13/20233016760Borrelia burgdorferi VlsE1/pepC10 Antibodies, CSF, Total by ELISA With Reflex to IgM and IgG by Immunoblot (Standard Two-Tier Testing, CSF)86618; if reflexed, add 86617 x2
11/13/20233016761Borrelia burgdorferi Antibodies, IgG and IgM by Immunoblot (CSF) Reflex86617 x2
11/13/20233016794Recoverin Antibody, IgG by Immunoblot, Serum84182
11/13/20233016795Histoplasma and Blastomyces by PCR87798 x2
11/13/20233016801CY 88121G Bladder Cancer FISH88121
11/13/20233016804Autoimmune Vision Loss Panel, Serum84182, 86255; if reflexed, add 86256
11/13/20233016817Celiac Disease Reflexive Cascade, Serum86364; if reflexed additional CPT codes may apply: 86364, 86231; 86258 x2
11/13/20233016839JAK2 (V617F) Mutation by ddPCR, Qualitative With Reflex to CALR (Calreticulin) Exon 9 Mutation Analysis by PCR and MPL Mutation Detection81270; if reflexed add 81219 and 81338
11/13/20233016840JAK2 (V617F) Mutation by ddPCR, Qualitative With Reflex to JAK2 Exon 12 Mutation Analysis by PCR81270; if reflexed, add 81279
11/13/20233016853Myelin Oligodendrocyte Glycoprotein (MOG) Antibody, IgG by CBA-IFA With Reflex to Titer, CSF86362; if reflexed, add 86256
11/13/20233016856Myelin Oligodendrocyte Glycoprotein (MOG) Antibody Titer, IgG, CSF (Reflex of 3016853 MOG CSF - Not orderable by clients)86256
11/13/20233016858von Willebrand Factor (VWF) Collagen III Binding0279U
11/13/20233016860Tissue Transglutaminase Antibody, IgA86364
11/13/20233016861Tissue Transglutaminase Antibody, IgA With Reflex to Endomysial Antibody, IgA by IFA86364; if reflexed, add 86231
11/13/20233016866Cortisol by LC-MS/MS, Salivary82533
11/13/20233016875Twin Zygosity81265
11/13/20233016908Huntington Disease (HD) CAG Repeat Expansion81271
11/13/202330169205-Hydroxyindoleacetic Acid (HIAA), Plasma83497
11/13/20233016927Factor 13, Qualitative, With Reflex to Factor 13 1:1 Mix85291; if reflexed, add 85291
11/13/20233016928Factor 13 1:1 Mix85291
11/1/20233016966Antibody Screen RBC, DTT86850, 86970
10/23/20233016621Myeloid Malignancies Mutation and Copy Number Variation Panel by Next Generation Sequencing81455
10/11/20233016943Human Papillomavirus (HPV) High Risk Screen, by Transcription-Mediated Amplification (TMA), ThinPrep87624
10/11/20233016944Human Papillomavirus (HPV) Genotypes 16 and 18/45, by Transcription-Mediated Amplification (TMA), ThinPrep87625
10/11/20233016945Human Papillomavirus (HPV) High Risk Screen by Transcription-Mediated Amplification (TMA), with Reflex to Genotypes 16 and 18/45, ThinPrep87624; if reflexed, add 87625
10/2/20233016932Vitamin B7, Serum or Plasma84591
9/27/20233016767Anti-Phospholipase A2 Receptor (PLA2R) Antibody, IgG by ELISA83516
9/26/20233016815Candida auris Surveillance CultureCulture: 87102, Identification: Varies based on method.
9/11/20233016879CD30 for Bone Marrow Specimens by Immunohistochemistry88342
9/5/20233016813Pepsin A, Respiratory83986, 84157, 83516
9/5/20233016847Herpes Simplex Virus Type 1 and 2 Antibodies, IgG by Western Blot, Serum86695, 86696
8/28/20233016788OLIG2 by Immunohistochemistry88342
8/22/20233016782SSTR2 by Immunohistochemistry88342
8/21/20233001591Comprehensive Epilepsy Panel, Sequencing and Deletion/Duplication81419
8/21/20233004583Drug Detection Panel, Meconium, Qualitative80326; 80347; 80364; 80355; 80323 (Alt code: G0481)
8/21/20233006366Pharmacogenetics Panel: Psychotropics, with GeneDose Access81225; 81226; 81227; 81230; 81231; 81291; 81479; if reflexed, add 81479
8/21/20233006373Drug Detection Panel and THC Metabolite, Meconium, Qualitative80326; 80347; 80364; 80355; 80349; 80323 (Alt code: G0481)
8/21/20233016503Thiopurine Metabolites in Red Blood Cells80299 (Alt code: G0480)
8/21/20233016579Beta-hCG, Quantitative (Pregnancy)84702
8/21/20233016583Exome Sequencing81415: per familial comparator, 81416 is added
8/21/20233016589Exome Sequencing, Familial ControlNA
8/21/20233016598Body Fluid, Creatinine82570
8/21/20233016604CSF, Total Protein84157
8/21/20233016614CSF, Glucose82945
8/21/20233016616Hemoglobin S Evaluation with Reflex to RBC Solubility83021; if reflexed, add 85660
8/21/20233016632Cyclic Citrullinated Peptide Antibody, IgG and IgA86200
8/21/20233016634Rheumatoid Arthritis (RA) Panel86200; 86431; 83516
8/21/20233016635Rheumatoid Arthritis (RA) Panel with Reflex to Rheumatoid Factors, IgA, IgG, and IgM by ELISA86200; 86431; 83516 if reflexed, add 83516 x3
8/21/20233016639Red Blood Cell Antigen Genotyping, Fetal0001U; 81265 Fetal Cell Contamination (FCC)
8/21/20233016640RhD Gene (RHD) Copy Number, Fetal81403; 81265 Fetal Cell Contamination (FCC)
8/21/20233016646Urine, Amylase82150
8/21/20233016649Urine, Glucose82945
8/21/20233016654Acute Myeloid Leukemia Panel by FISH88271 x7; 88275 x7
8/21/20233016673Platelet Antigen Genotyping Panel, Fetal81105; 81106; 81107; 81108; 81109; 81110; 81112; 81265 Fetal Cell Contamination (FCC)
8/21/20233016676Kell K/k (KEL) Antigen Genotyping, Fetal0001U; 81265 Fetal Cell Contamination (FCC)
8/21/20233016679RhC/c (RHCE) Antigen Genotyping, Fetal0001U; 81265 Fetal Cell Contamination (FCC)
8/21/20233016682RhE/e (RHCE) Antigen Genotyping, Fetal0001U; 81265 Fetal Cell Contamination (FCC)
8/21/20233016687Coccidioides by PCR87798
8/14/20233016567INSM1 by Immunohistochemistry88342
8/7/20233016752Vitamin B3 (Niacin and Metabolites), Serum/Plasma84591
8/7/20233016769Anti-Dense Fine Speckled 70 (DFS70) Antibody by ELISA, Serum86038
7/17/20233016533Envoplakin Antibody, IgG by ELISA83516
7/17/20233016534Paraneoplastic Pemphigus (Paraneoplastic Autoimmune Multiorgan Syndrome) Expanded Antibody Panel by IIF With ELISA88346; 88350 x3; 83516
7/10/20233016552CD103 by Immunohistochemistry88342
7/10/20233016561Annexin A1 by Immunohistochemistry88342
7/7/20233000959AAV5 Detect CDxTM -AAV5 Total Antibody Assay for ROCTAVIAN (valoctocogene roxaparvovec-rvox) Eligibility in Hemophilia A 
7/6/20233016457Pneumonia Panel by PCR87633
6/26/20233006379Hepatitis Delta Virus Antibody by ELISA With Reflex to Hepatitis Delta Virus by Quantitative PCR86692; if reflexed, add 87799
6/26/20233016631HBV Exposure Panel86706; 86704; 87340; if reflexed, add 87341
6/20/20233016694Trypsin, Serum83519
6/12/20233016493Whole Genome Sequencing81425; per familial comparator, 81426 is added
6/12/20233016493Whole Genome Sequencing81425; per familial comparator, 81426 is added
5/23/20233006357NR4A3 Rearrangement by FISH88366
5/22/20233006344Mycoplasmoides genitalium Detection and Macrolide Resistance by PCR87798, 87563
5/22/20233006367Tickborne Disease Antibodies Panel86753; 86666 x2; 86618; if reflexed, add 86617 x2
5/15/20233001868Acetylcholine Receptor Binding Antibody with reflex to Muscle-Specific Kinase (MuSK) Ab, IgG83519; if reflexed, add 86255; if reflexed, add 86256
5/15/20233001869Myasthenia Gravis Reflexive Panel83519; 83516; if reflexed, add 83516 or 86255; if reflexed, add 86256
5/15/20233005949Aldosterone and Renin Direct, With RatioRefer to Aldosterone (0070015) and Renin, Direct (2001575)
5/15/20233006198Muscle-Specific Kinase (MuSK) Antibody, IgG by CBA-IFA with Reflex to Titer, Serum86255; if reflexed, add 86256
5/15/20233006201Autoimmune Encephalopathy/Dementia Panel, Serum86341; 84182 x2; 86255 x10; if reflexed, add 84182 x4; 86256 per titer
5/15/20233006202Autoimmune Encephalopathy/Dementia Panel, CSF86341; 84182 x2; 86255 x10; if reflexed, add 84182 x4; 86256 per titer
5/15/20233006203Autoimmune Dysautonomia Panel, Serum83519; 86255 x5; if reflexed, add 84182; 86256 per titer
5/15/20233006204Autoimmune Epilepsy Panel, Serum86341; 84182 x2; 86255 x10; if reflexed, add 84182 x4; 86256 per titer
5/15/20233006205Autoimmune Epilepsy Panel, CSF86341; 84182 x2; 86255 x10; if reflexed, add 84182 x4; 86256 per titer
5/15/20233006206Autoimmune Movement Disorder Panel, Serum86341; 86596; 84182 x2; 86255 x12; if reflexed, add 84182 x4; 86256 per titer
5/15/20233006207Autoimmune Movement Disorder Panel, CSF86341; 84182 x2; 86255 x12; if reflexed, add 84182 x4; 86256 per titer
5/15/20233006208Autoimmune Myelopathy Panel, Serum86341; 86362; 86052; 84182 x2; 86255 x5; if reflexed, add 84182 x4; 86256 per titer
5/15/20233006209Autoimmune Myelopathy Panel, CSF86341; 86052; 84182 x2; 86255 x5; if reflexed, add 84182 x4; 86256 per titer
5/15/20233006210Autoimmune Pediatric CNS Disorders, Serum86341; 86362; 86052; 86255 x8; if reflexed, add 84182 x2; 86256 per titer
5/15/20233006211Autoimmune Pediatric CNS Disorders, CSF86341; 86052; 86255 x8; if reflexed, add 84182 x2; 86256 per titer
5/15/20233006234Autoimmune Stiff-Person Disorders, Serum86341; 84182; 86255; if reflexed, add 86256
5/15/20233006235Autoimmune Stiff-Person Disorders, CSF86341; 84182; 86255; if reflexed, add 86256
5/15/20233006247Angelman Syndrome and Prader-Willi Syndrome by Methylation-Specific MLPA81331; for fetal specimens add 81265
5/15/20233006297Luteinizing Hormone by Immunohistochemistry88342
5/15/20233006300Follicle Stimulating Hormone by Immunohistochemistry88342
5/15/20233006343Prenatal Hepatitis Panel87340; 86803; if reflexed, add 87341; 87522
5/15/20233006371Drug Detection Panel and THC Metabolite, Umbilical Cord Tissue, Qualitative80326; 80347; 80364; 80355; 80349 (Alt code: G0481)
5/15/20233006373Drug Detection Panel and THC Metabolite, Meconium, Qualitative80326; 80347; 80364; 80355; 80349 (Alt code: G0481)
5/15/20233006383Prolonged Clot Time Reflexive Profile85390-26; additional CPT codes may apply: 85210; 85220; 85230; 85240; 85245; 85246; 85250; 85260; 85270; 85280; 85335; 85379; 85384; 85385; 85525; 85597; 85598; 85610; 85611; 85613; 85635; 85670; 85730; 85732
5/11/20233002638SARS-CoV-2 (COVID-19) by NAA87635
5/1/20233006254JC Virus Antibody by ELISA, Serum with Reflex to Inhibition Assay86711; if reflexed, add 86711
5/1/20233016444Phospho-Tau/Total-Tau/A Beta42, CSF83520 x3
4/24/20233006149BRAF by Immunohistochemistry88342
4/24/20233006162IRF8 by Immunohistochemistry88342
4/24/20233006370Candida auris by PCR87481
4/18/20233006351Cathepsin K by Immunohistochemistry88342
4/3/20233006271Helicobacter pylori, Breath Test83013
3/28/20233006178Isobutyryl/butyryl-carnitine (C4) Quantitative, Urine82017
3/27/20233006053Borrelia burgdorferi VlsE1/pepC10 Antibodies, Total by ELISA With Reflex to IgM and IgG by ELISA (Modified Two-Tier Testing)86618; if reflexed, add 86618 x2
3/20/20233005674Genital Ulcer Disease Panel by PCR87491, 87529 x2, 87798 x2
3/15/20233005939Rapid Whole Genome Reanalysis81427
3/7/20232002290Chromosome Analysis, Leukemic Blood88237; 88264; for COG studies, add 88299
3/7/20232002292Chromosome Analysis, Bone Marrow88237; 88264; for COG studies, add 88299
3/7/20232007130Chromosome Analysis, Bone Marrow with Reflex to Genomic Microarray88237; 88264; if reflexed, add 81277; for COG studies, add 88299
3/7/20232007131Chromosome Analysis, Leukemic Blood with Reflex to Genomic Microarray88237; 88264; if reflexed, add 81277; for COG studies, add 88299
3/6/20233006285Adiponectin Quantitative, Serum/Plasma83520
2/28/20233006242Mycobacterium Tuberculosis by Immunohistochemistry88342
2/27/20233005935Rapid Whole Genome Sequencing81425; per familial comparator, 81426 is added
2/27/20233005939Rapid Whole Genome Reanalysis81417
2/21/20233000477Hypersensitivity Pneumonitis Panel86331 x5; 86606 x5
2/21/20233001561Hypersensitivity Pneumonitis Extended Panel (Farmer's Lung Panel)86003 x3; 86005; 86331 x5; 86606 x5
2/21/20233001633Hereditary Central Nervous System Cancer Panel, Sequencing and Deletion/Duplication81201; 81203; 81403; 81404; 81405; 81406; 81407; 81408; 81479
2/21/20233002673Hereditary Melanoma Panel, Sequencing and Deletion/Duplication81167; 81216; 81404; 81321; 81323; 81351; 81479
2/21/20233005912Hereditary Paraganglioma-Pheochromocytoma Expanded Panel, Sequencing and Deletion/Duplication81437; 81438
2/21/20233005944Hereditary Thyroid Cancer Panel, Sequencing and Deletion/Duplication81201; 81203; 81404; 81405; 81321; 81323; 81406; 81351; 81479
2/21/20233005960Complement C5, Functional86161
2/21/20233005961C5 Inhibitors Drug Monitoring Panel86160; 86161 x2; 86162
2/21/20233005963Hereditary Gastric Cancer Panel, Sequencing and Deletion/Duplication81201; 81203; 81292; 81294; 81295; 81297; 81298; 81300; 81317; 81319; 81403
2/21/20233005976Free Thyroxine Index Panel84479; 84436
2/21/20233005977T Uptake84479
2/21/20233005978Thyroxine, Total T484436
2/21/20233005996Triglycerides Body Fluid with Reflex to Chylomicron Electrophoresis84478; if reflexed, add 82664
2/21/20233006003Gamma-Aminobutyric Acid Receptor, Type A (GABA-AR) Antibody, IgG by CBA-IFA with Reflex to Titer, CSF86255; if reflexed, add 86256
2/21/20233006008Gamma-Aminobutyric Acid Receptor, Type A (GABA-AR) Antibody, IgG by CBA-IFA with Reflex to Titer, Serum86255; if reflexed, add 86256
2/21/20233006013IgLON Family Member 5 (IgLON5) Antibody, IgG by CBA-IFA With Reflex to Titer, CSF86255; if reflexed, add 86256
2/21/20233006018IgLON Family Member 5 (IgLON5) Antibody, IgG by CBA-IFA With Reflex to Titer, Serum86255; if reflexed, add 86256
2/21/20233006023Inositol 1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Antibody, IgG by CBA-IFA With Reflex to Titer, CSF86255; if reflexed, add 86256
2/21/20233006031Inositol 1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Antibody, IgG by CBA-IFA With Reflex to Titer, Serum86255; if reflexed, add 86256
2/21/20233006039Metabotropic Glutamate Receptor 1 (mGluR1) Antibody, IgG by CBA-IFA With Reflex to Titer, CSF86255; if reflexed, add 86256
2/21/20233006044Metabotropic Glutamate Receptor 1 (mGluR1) Antibody, IgG by CBA-IFA With Reflex to Titer, Serum86255; if reflexed, add 86256
2/21/20233006049Autoimmune Encephalitis Reflex Panel, CSF86052; 86255 x9; 83519; 86341; if reflexed, add 86256 per titer.
2/21/20233006050Autoimmune Encephalitis Extended Panel, Serum83519; 86052; 86341; 86362; 86255 x9; if reflexed, add 86256 per titer.
2/21/20233006051Autoimmune Neurologic Disease Panel with Reflex, Serum83519 x2; 84182 x2; 86255 x12; 86341; 86052; 86362; 86596; if reflexed, add 83519; 84182 x4; 86256 per titer
2/21/20233006052Autoimmune Neurologic Disease Panel With Reflex, CSF86255 x12; 83519; 86341; 84182 x2; if reflexed, add 84182 x4; 86256 per titer
2/21/20233006065Hypersensitivity Pneumonitis 186331 x3; 86606 x2
2/21/20233006066Toxocara Antibodies, IgG by ELISA86682
2/21/20233006075BK Virus by Quantitative NAAT, Urine87799
2/21/20233006076BK Virus by Quantitative NAAT, Plasma87799
2/21/20233006079Epstein-Barr Virus by Quantitative NAAT, Plasma87799
2/21/20233006168Thyroid Stimulating Hormone by Immunohistochemistry88342
2/6/20232013484TP53 Somatic Mutation, Prognostic81352
2/6/20233005983Merkel Cell Carcinoma Antibodies0058U
2/1/20232005003Paroxysmal Nocturnal Hemoglobinuria, High Sensitivity, WBC86356 x4
2/1/20232005006Paroxysmal Nocturnal Hemoglobinuria (PNH), High Sensitivity, RBC and WBC86356 x6
1/1/20230092066Thiopurine Methyltransferase, RBC84433
1/1/20232007862Ehrlichia and Anaplasma Species by PCR87468; 87484; 87798 x2
1/1/20232008665Babesia Species by PCR87469; 87798
1/1/20232008670Tick-Borne Disease Panel by PCR, Blood87468; 87484; 87798 x3; 87469
12/20/20223006111ST2, Soluble83006
12/9/20223005393Chimerism, Posttransplant, Sorted Cells (T Cells)81268
12/9/20223005401Chimerism, Posttransplant, Sorted Cells (B Cells)81268
12/9/20223005409Chimerism, Posttransplant, Sorted Cells (CD33+ Cells)81268
12/9/20223005417Chimerism, Posttransplant, Sorted Cells (Granulocytes)81268
12/9/20223005425Chimerism, Posttransplant, Sorted Cells (Monocytes)81268
12/9/20223005433Chimerism, Posttransplant, Sorted Cells (CD34+ Cells)81268
12/9/20223005441Chimerism, Posttransplant, Sorted Cells (CD 56+ Cells)81268
12/5/20223005941Histoplasma Galactomannan Antigen by EIA, Quantitative, Body Fluid87385
12/5/20223005956MGMT Promoter Methylation Detection by ddPCR81287
11/15/20223005900PHOX2B by Immunohistochemistry88342
11/14/20220040248KRAS Mutation Detection81275; 81276
11/14/20220051415Ashkenazi Jewish Diseases, 16 Genes81401; 81209; 81200; 81260; 81242; 81251; 81250; 81479; 81205; 81290; 81400; 81330; 81255
11/14/20220051750BRAF Codon 600 Mutation Detection with Reflex to MLH1 Promoter Methylation81210; If reflexed, add 81288
11/14/20222002327Mismatch Repair by Immunohistochemistry with Reflex to BRAF Codon 600 Mutation and MLH1 Promoter Methylation88342; 88341 x3; if reflexed, add 81210; if further reflexed, add 81288
11/14/20222002440EGFR Mutation Detection by Pyrosequencing81235
11/14/20222002498BRAF Codon 600 Mutation Detection by Pyrosequencing81210
11/14/20222003123NRAS Mutation Detection by Pyrosequencing81311
11/14/20222005270Mismatch Repair by Immunohistochemistry with Reflex to MLH1 Promoter Methylation88342; 88341 x3; if reflexed, add 81288
11/14/20222008863Holoprosencephaly Panel, Sequencing and Deletion/Duplication, Fetal81479; 81265
11/14/20222009310MGMT Promoter Methylation Detection (Change effective as of 12/05/2022: Refer to 3005956 in the December Hotline)81287
11/14/20222010769Noonan Spectrum Disorders Panel, Sequencing, Fetal81442; 81265
11/14/20222012010Skeletal Dysplasia Panel, Sequencing and Deletion/Duplication, Fetal81405; 81408; 81479; 81265
11/14/20223000894Hereditary Hemolytic Anemia Cascade84220; 88184; 82955; 83021. Reflex components billed separately. Additional CPT codes may apply, 85555; 85060; 85007; 83068; 81269; 81259; 81363; 81364; 81249; 81443; 85660; 83020; 81479
11/14/20223001615Hereditary Bone Marrow Failure Panel, Sequencing and Deletion/Duplication81443; for skin punch biopsy, add 88233
11/14/20223002096Tuberous Sclerosis Complex Panel, Sequencing and Deletion/Duplication, Fetal81405; 81406; 81407; 81265
11/14/20223002134IDH1 R132H Point Mutation by Immunohistochemistry with Reflex to IDH1 and IDH2 Mutation Analysis, Exon 488342; if reflexed, add 81120; 81121
11/14/202230021351p19q Deletion by FISH and IDH1 R132H Point Mutation by Immunohistochemistry with Reflex to IDH1 and IDH2 Mutation Analysis, Exon 488342; 88377 x2; if reflexed, add 81120; 81121
11/14/20223004267IDH1 and IDH2 Mutation Analysis Exon 4, Formalin-Fixed, Paraffin-Embedded (FFPE) Tissue81120; 81121
11/14/20223004273Cytogenomic Molecular Inversion Probe Array FFPE Tissue - Products of Conception81229
11/14/20223004275Cytogenomic Molecular Inversion Probe Array FFPE Tissue - Oncology81277
11/14/20223004277Microsatellite Instability (MSI) HNPCC/Lynch Syndrome by PCR81301
11/14/20223004279Gastrointestinal Stromal Tumor Mutations81272; 81314
11/14/20223004283KIT Mutations Melanoma81272; 81314
11/14/20223004294Solid Tumor Mutation Panel, Sequencing81445
11/14/20223004308MLH1 Promoter Methylation81288
11/14/20223005632Hereditary Breast Cancer High-Risk Panel, Sequencing and Deletion/Duplication81162; 81406; 81307; 81321; 81323; 81351; 81479
11/14/20223005654Hereditary Breast Cancer Guidelines-Based Panel, Sequencing and Deletion/Duplication81408; 81479; 81162; 81406; 81307; 81321; 81323; 81404; 81405; 81351
11/14/20223005686Hereditary Prostate Cancer Panel, Sequencing and Deletion/Duplication81408; 81162; 81403; 81292; 81294; 81295; 81297; 81298; 81300; 81307; 81317; 81319; 81351; 81479
11/14/20223005696Hereditary Retinoblastoma (RB1) Sequencing and Deletion/Duplication81479
11/14/20223005697Hereditary Gastrointestinal Cancer High-Risk Panel, Sequencing and Deletion/Duplication81201; 81203; 81292; 81294; 81295; 81297; 81298; 81300; 81406; 81317; 81319; 81479
11/14/20223005703Birt-Hogg-Dube Syndrome (FLCN) Sequencing and Deletion/Duplication81479
11/14/20223005708Hereditary Pancreatic Cancer Panel, Sequencing and Deletion/Duplication81201; 81203; 81408; 81162; 81292; 81294; 81295; 81297; 81298; 81300; 81307; 81317; 81319; 81404; 81405; 81351; 81403; 81479
11/14/20223005714DNA Extract and HoldN/A
11/14/20223005721Hereditary Erythrocytosis Panel, Sequencing81364, 81404; 81479; for skin punch biopsy, add 88233
11/14/20223005839Diagnostic Qualitative BCR-ABL1 Assay with Reflex to p190 or p210 Quantitative Assays81206; 81207; 81208; If reflexed, add 81206 or 81207
11/14/20223005840Quantitative Detection of BCR-ABL1, Major Form (p210)81206
11/14/20223005859Sertraline, Serum or Plasma80332 (Alt code: G0480)
11/14/20223005860Trazodone, Serum/Plasma80338 (Alt code: G0480)
11/14/20223005863Transforming Growth Factor beta1, Plasma83520
11/14/20223005865Transforming Growth Factor beta1, Serum83520
11/14/20223005867Familial Targeted Sequencing81403
11/14/20223005869Familial Targeted Sequencing, Fetal81403; 81265 Fetal Cell Contamination (FCC)
11/14/20223005874Kratom, Umbilical Cord, Qual80323 (Alt code: G0480)
11/14/20223005882Dysautonomia, Familial (ELP1), 2 Variants81260
11/14/20223005895Cytomegalovirus by Quantitative NAAT, Plasma87497
11/8/20223004508Cytomegalovirus Drug Resistance by Next Generation Sequencing, Ganciclovir, Foscarnet, Cidofovir, and Maribavir87910; 87900
11/8/20223004509Cytomegalovirus Drug Resistance by Next Generation Sequencing, Letermovir87910; 87900
11/8/20223004615Cytomegalovirus Drug Resistance by Next Generation Sequencing, Ganciclovir, Foscarnet, Cidofovir, Maribavir, and Letermovir87910; 87900
11/7/20223005925Ustekinumab Quantitation with Antibodies, Serum80299; 83520
10/25/20223005916CIC (19q13.2) Gene Rearrangement by FISH88366
10/14/20223004833Drug Profile, Expanded Targeted Panel by LC-MS/MS, Serum/Plasma80323; 80326; 80329; 80334; 80337; 80338; 80341; 80344; 80346; 80348; 80353; 80354; 80356; 80357; 80358; 80359; 80360; 80361; 80363; 80365; 80366; 80368; 80370; 80371; 80372; 80373; 80377; 83992 (Alt code: G0482)