Chronic lymphocytic leukemia (CLL) is the most common form of leukemia in adults in the United States and represents 40% of all adult leukemias in Western countries.

Chronic lymphocytic leukemia (CLL) is characterized by small lymphocytes in the bone marrow, blood, and lymphoid tissues.

Testing

Cytogenetic, molecular, and flow cytometric testing play an important role in prognostication for patients with CLL.

Indications for Testing—Adult with persistent, unexplained lymphocytosis of ≥3 months' duration found on CBC; lymphadenopathy

chronic lymphocytic leukemia Chromosome fish CLL Panel Cytogenomic SNP Microarray , CD38, IGHV, Chromosome analysis Leukemic blood or Bone Marrow
 

For additional information regarding testing strategies, refer to our Chronic lymphocytic leukemia (CLL) test search.

Additional Resources

ARUP’s hematologic cancer experts are nationally and internationally recognized pathologists, subspecialty-qualified clinicians, and board-certified clinical scientists.

ARUP Consult® is a laboratory test selection support tool with more than 2,000 lab tests categorized into topics and algorithms. Visit the ARUP Consult—Chronic Lymphocytic Leukemia - CLL topic.