Testosterone and Estrogen

February 3, 2022

Important Test Updates

Updates to Testosterone and Estrogen Test Information Will Promote Inclusivity and Facilitate Test Selection


Effective February 22, 2022, ARUP Laboratories will update test names, ordering recommendations, and chartable interpretive comments associated with our testosterone and estrogen tests.

These updates will:

  • Promote inclusivity as the field of testosterone and estrogen testing evolves to better address the needs of diverse patient populations.
  • Aid clinicians in choosing the right test for a wide array of clinical scenarios, including testing for hypogonadism, monitoring gender-affirming hormone therapies, and monitoring estrogen- or androgen-suppressing cancer therapies.
  • Reflect ARUP's dedication to providing quality, patient-focused testing for all populations.

What test information will be updated?

  • Test names
  • Ordering recommendations
  • Chartable interpretive comments

Important: Reference intervals are not affected by these updates.

Enhanced decision support materials (e.g., updated ARUP Consult topics and testing algorithms) related to testosterone and estrogen testing will also be available.

Reasons for This Update

Accurate measurement of testosterone and estrogen is dependent on many factors, such as hormone concentration or phase of hormone therapy. These factors are important to consider when choosing related endocrine tests and can make it difficult to select the correct test. 

By providing additional information in test names, ordering recommendations, and chartable interpretive comments (including clinical scenario, methods, expected hormone concentrations, and recommended alternative tests), these updates will reduce confusion surrounding test selection and aid clinicians in choosing the appropriate test.

Benefits

  • Reduce costs and save time with improved test utilization patterns
  • Provide efficient, high-quality testing for diverse clinical scenarios
  • Improve care for patients on hormone therapy
Affected Testosterone Tests

Test Code

Updated Test Name

0070130

Testosterone (Adult Males or Individuals on Testosterone Hormone Therapy)

0081058

Testosterone (Adult Females, Children, or Individuals on Testosterone-Suppressing Hormone Therapy)

0070111

Testosterone, Free (Adult Males or Individuals on Testosterone Hormone Therapy)

0081059

Testosterone, Free (Adult Females, Children, or Individuals on Testosterone-Suppressing Hormone Therapy)

2003246

Testosterone, Free, by Dialysis and Mass Spectrometry (Adult Males or Individuals on Testosterone Hormone Therapy)

0070109

Testosterone, Free and Total, Includes Sex Hormone-Binding Globulin (Adult Males or Individuals on Testosterone Hormone Therapy)

0081056

Testosterone, Free and Total, Includes Sex Hormone-Binding Globulin (Adult Females, Children, or Individuals on Testosterone-Suppressing Hormone Therapy)

2004246

Testosterone, Free and Total, by Dialysis and Mass Spectrometry (Adult Males or Individuals on Testosterone Hormone Therapy)

0070102

Testosterone, Bioavailable and Total, Includes Sex Hormone-Binding Globulin (Adult Males or Individuals on Testosterone Hormone Therapy)

0081057

Testosterone, Bioavailable and Total, Includes Sex Hormone-Binding Globulin (Adult Females, Children, or Individuals on Testosterone-Suppressing Hormone Therapy)
Affected Estrogen Tests

Test Code

Updated Test Name

0070045

Estradiol (Adult Premenopausal Females or Individuals on Estrogen Hormone Therapy)

0093247

Estradiol (Adult Males, Children, Postmenopausal Females, or Individuals on Estrogen-Suppressing Hormone Therapy)

0093248

Estrogens, Fractionated, by Mass Spectrometry

0093249

Estrone, by Mass Spectrometry

2006160

Estradiol, Free, by Dialysis and Mass Spectrometry 

Live Webinar

Inclusivity in Laboratory Medicine: Endocrine Testing in Transgender Individuals

March 24, 2022 | 11:00 a.m.–Noon MDT


Joely Straseski, PhD, MS, MT(ASCP), DABCC
Section Chief, Clinical Chemistry and
Medical Director, Endocrinology and Automated Core Laboratory
ARUP Laboratories
Professor (Clinical), University of Utah School of Medicine

Register to join us for this live webinar.

If you have additional questions, please contact ARUP Client Services and use keyword: TESTOSTERONE AND ESTROGEN UPDATES

Contact ARUP Client Services

call 1-800-522-2787 | online chat aruplab.com | email clientservices@aruplab.com