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Human Papillomavirus (HPV) Testing Highlights
Human papillomavirus (HPV) is the most common sexually transmitted viral infection in the United States.
Most HPV infections are benign and resolve on their own, but persistent infection with any of the high-risk HPV genotypes increases a woman’s risk for developing cervical cancer.
To assist in the detection and surveillance of HPV infections, ARUP offers multiple molecular screening and testing options based on current cervical cancer screening guidelines from the American College of Obstetricians and Gynecologists (ACOG), the American Society for Colposcopy and Cervical Pathology (ASCCP), the United States Preventive Services Task Force (USPSTF), and the American Cancer Society (ACS).
Why Choose ARUP?
Flexible Testing Options
Clinicians have the ability to order the testing indicated for individual patient populations.
Cost Saving Opportunities
ARUP offers multiple HPV testing options at various price points.
Reliable Results
ARUP’s screening tests detect 14 high-risk HPV genotypes in a single analysis, differentiates HPV16 and HPV18 from other high-risk types, and aligns reporting with current cervical cancer screening guidelines.
Additional Resources
- For more information on testing options, visit the ARUP Human Papillomavirus Consult topic.
- Visit ARUP’s test directory for additional HPV offerings.
Education
An Update on HPV Versus Non-HPV-Associated Endocervical Adenocarcinoma
Video Lecture by Lesley C. Lomo, MD
Pathologist
HPV Screening Tests
| Test Name | Test Number | Test Utility | Result Type | HPV Genotypes Tested and Reported |
|---|---|---|---|---|
| Human Papillomavirus (HPV) High Risk Screen by Transcription-Mediated Amplification (TMA), with Reflex to Genotypes 16 and 18/45, ThinPrep | 3016945 | HPV screen with reflex to genotyping This assay is a screening method with additional genotype differentiation | Detected/Not Detected Detected results reported with genotype differentiation | 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68 If detected, high-risk genotypes HPV 16 and HPV 18/45 will be reported |
| Human Papillomavirus (HPV) High Risk Screen, by Transcription-Mediated Amplification (TMA), ThinPrep | 3016943 | HPV screen only This assay is the preferred screening method for HPV | Detected/Not Detected | 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68 If high-risk genotypes are present, reported as “detected”
|
| Human Papillomavirus (HPV) Genotypes 16 and 18/45, by Transcription-Mediated Amplification (TMA), ThinPrep | 3016944 | Genotyping only | Genotype differentiation | 16 and 18/45 If detected, high-risk genotypes HPV 16 and HPV 18/45 will be reported |
| HPV Primary Screen by PCR w/ Reflex to Cytology | 3016636 | Screen with reflex to cytology | Positive/Negative Positive results reported with genotype differentiation Cytology by report | 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68 If detected, high-risk genotypes HPV 16 and HPV 18 will be differentiated, and specimen will be reflexed to cytology |
| Human Papillomavirus (HPV), High Risk with 16 and 18 Genotype by PCR, ThinPrep | 2011940 | This assay is a screening method with additional genotype differentiation | Positive/Negative Positive results reported with genotype differentiation | 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68 If detected, high-risk genotypes HPV 16 and HPV 18/45 will be reported |
| Human Papillomavirus (HPV), High Risk with 16 and 18 Genotype by PCR, SurePath | 2011933 | This assay is a screening method with additional genotype differentiation | Positive/Negative Positive results reported with genotype differentiation | 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68 If detected, high-risk genotypes HPV 16 and HPV 18/45 will be reported will be reported |
