Publications

The ARUP Institute for Clinical and Experimental Pathology^® is focused on the development of new diagnostic assays in a wide range of disciplines. Researchers at the institute regularly publish in respected, peer-reviewed journals, give presentations at national and international organizations, author books and book chapters, and develop new tests.

Publications by Year

Recent Publications

Frater JL, George TI. An update on the activities of the International Society for Laboratory Hematology, 2026. Int J Lab Hematol. Published online Apr 2026.

Wellman EA, Conlon JD, Leiferman KM, Wilson ML. Anti-p200 pemphigoid in an infant clinically mimicking linear IgA disease. Pediatr Dermatol. Published online Apr 2026.

Shean RC, Tardif KD, Rangel A, Dutrschi J, Bogumil D, Cruse A, Hernandez S, Iremadze N, Pollock S, Lipson D, Bradley BT. Evaluation of the Ultima Genomics UG 100 sequencer for low-cost, high-sensitivity metagenomic pathogen detection from cerebrospinal fluid. Microbial Spectr. 2026;14(4):e0187425.

Kanack A, Mauch E, Roberge G, Splinter N, Gundabolu K, Wool GD, George G, Abou-Ismail MY, Smock KJ, Green DL, Coker J, Kohlhagen MC, Murray DL, Padmanabhan A. platelet factor 4 antibody persistence and long-term pathogenicity in vaccine-induced immune thrombotic thrombocytopenia. J Thromb Haemost. 2026;S1538-7836(26)00215-1.

Ohgami RS. New updates and guidelines in T-cell nomenclature relevant to molecular pathology. J Mol Diagn. 2026;28(4):323-324.

Shean RC, George TI, Ng DP. Characterization of CD123 expression by mast cells in systemic mastocytosis with multicolor flow cytometry. Cytometry B Clin Cytom. Published online Mar 2026.

Alnoor F, Mukherjee S, Menon MP, Ng D, Li P, Ohgami RS. Molecular pathology, artificial intelligence, and new technologies in hematologic diagnostics: translational opportunities and practical considerations. Diagnostics (Basel). 2026;16(6):913.

Wilcock D, Jedrzkiewicz J, Cleary AS, Beech C, Gulbahce HE. Breast cancers with discordant human epidermal growth factor receptor 2 fluorescence in situ hybridization-positive (group 1) and immunohistochemistry-negative (0/1+) results following American Society of Clinical Oncology/College of American Pathologists guideline. Arch Pathol Lab Med. Published online Mar 2026.

Sanchez Oviol Z, Sorensen ES, Carmona P, Zumberg MS, Smock KJ, Moser K, Chen D, Harris NS, Marin MJ. A diagnostic journey through a rare hemostatic disorder. J Appl Lab Med. Published online May 2026.

Salazar E, Smock KJ, Cazzolli T, Dlott JS, Lickteig N, Long TA, Mulvey JJ, Gil MR, Rollins-Raval M, Teruya J, Volod O, Walker CA, Wool GD, Zantek ND, Goodwin Iv AJ. D-dimer reporting and harmonization: analysis of College of American Pathologists D-dimer proficiency testing program. Semin Thromb Hemost. Published online Mar 2026.

Vannucchi AM, Patel JL, Kiladjian JJ. Myeloid/lymphoid neoplasms with FGFR1 rearrangement and pemigatinib. Blood. Published online Mar 2026.

Maucione C, McLamb N, Zaydman MA, Pearson LN, Metcalf RA, Spies NC. Identification of IV fluid contamination in complete blood counts and subsequent unnecessary red blood cell transfusions using artificial intelligence. Transfusion. 2026;66(3):469-480.

Kuhre J, Jain M, Hohmann S, Enioutina EY. Usefulness of approved and newly emerging non-cultural assays for early detection of invasive fungal infections in pediatric patients: a scoping review. J Microbiol Methods. 2026;242:107389.

Boone PM, Erdin S, Mohamed A, Haghshenas S, Faour KNW, Kao E, Fu J, Auwerx C, Harripaul R, Jana B, Springer D, Hallstrom G, de Esch CEF, Denhoff E, Holmes L, Mohajeri K, Lemanski J, Kerkhof J, McConkey H, Rzasa J, McCune MJ, Levy MA, Grafstein J, Larson M, Wright Z, Beauchamp RL, Lucente D, Jamra RA, Agrawal N, Agrawal P, Andersen EF, Argilli E, Araiza R, Ballal S, Baxter MF, Bergant G, Bertsche A, Bhavsar R, Bortola DR, Bothe V, Brasch-Andersen C, Braun D, Bruel AL, Buchanan C, Burt ND, Carvalho LML, Chiriatti L, Cogne B, Collins R, Crunk A, Currall B, Delahaye-Duriez A, Delanne J, Denommé-Pichon AS, Devriendt K, Domingo A, Duncan L, Faivre L, Famularo L, Fulton A, Genetti C, Harel T, Havlovicova M, Higgs J, Houlier M, Iascone M, Immken L, Isidor B, Kaiser FJ, Karbone K, Kenna M, Khan A, Kimmig LK, Kleefstra T, Kraus EM, Krepischi ACV, Krey I, Ladda R, Lanoue L, Le Caignec C, Lewis ZK, Lima G, Lynch SA, Macek M Jr, Maier O, Maitz S, Male A, Malikova M, McKay V, Moldovan O, Monteil D, Oliveira MM, Munasinghe J, Nakamori S, Neuser S, Nizon M, Nuttle X, O'Keefe K, Orec L, Parenti I, Peterlin B, Pfundt R, Pouncey J, Radio FC, Robert L, Rodan L, Rosenberg-Fogler H, Rosenfeld JA, Safraou H, Salani M, Schliesske S, Seaby EG, Sell S, Eliot Shearer A, Sherr E, Shillington A, Siebold D, Sinnema M, Smith L, Stegmann APA, Stevens C, Stevens S, Surette E, Tartaglia M, Taylor JC, Thompson ML, Tørring PM, Mau Them FT, Tsoulaki O, Umair M, Vanhoutte E, Vincent M, Vitobello A, von Wintzingerode L, Watt A, Wayhelova M, Wentzensen IM, Wilson W, Wojcik MH, Yuan B, Zampino G, Srivastava S, Westphal DS, Riedhammer KM, Joyce E, Yadav R, Gusella J, Tai DJC, Sadikovic B, Pfeifer KE, Talkowski ME. Clinical, in vitro, and in vivo evidence of WAPL as a novel cohesinopathy gene and phenotypic driver of 10q22.3q23.2 genomic disorder. medRxiv. 2026:2026.02.23.26346364.

Crumpler M, Realegeno SE, Shakir SM, Hutton SM, Davis W, Ayala JC, Smith AC, Van Der Pol B. Review of the performance of laboratory-based molecular diagnostics for Chlamydia trachomatis and Neisseria gonorrhoeae. Clin Infect Dis. 2026;82(Supplement_1):S19-S35.

Christensen RD, Doyle K, Henry E, Bennett ST, Zeiler BB, Ilstrup SJ, Swenson EA, Bahr TM, Ohls RK. Reference intervals for circulating nucleated red blood cell counts of neonates, improved by the refineR algorithm. J Perinatol. Published online Feb 2026.

Attardi E, Gray N, Lewis S, Boals M, Shaker P, Kotmayer L, Sahoo SS, Li P, Andersen EF, Zhao J, Pizzo L, Oved JH, Jesudas R, Reiss UM, Sharma R, Christakopoulos GE, Bhoopalan SV, Takemoto CM, Kennedy A, Voso MT, Kang G, Wlodarski MW. Utility of peripheral blood testing for detection and surveillance of clonal hematopoiesis in predisposed individuals. Blood. 2026;147(8):897-901.

Siebenhaar F, Broesby-Olsen S, Castells M, George TI, Livideanu CB, Álvarez-Twose I, Panse J, Barete S, Reiter A, Dybedal I, Akin C, Van Daele P, Radia DH, Cerquozzi S, Ustun C, Sabato V, Gotlib J, Rafferty M, DeAngelo DJ, Schafhausen P, Ungerstedt J, Ogbogu PU, Florell S, Wada DA, Rets A, Lin HM, Bidollari I, Hong J, Shaheen D, Lampson B, Hartmann K. Avapritinib improves cutaneous involvement in patients with indolent systemic mastocytosis: results from the randomized, phase 2, interventional PIONEER study. J Am Acad Dermatol. 2026:S0190-9622(26)00221-5.

Mukherjee S, Lambert C, Zhou Y, Kan S, Yang J, Liao G, Flygare S, Ohgami RS. Collaborative robotics, mobile platforms, and total laboratory automation in clinical diagnostics. Diagnostics (Basel). 2026;16(4):518.

Boyd JM, McMillin GA. Unique issues when people try to beat the compliance drug test (adherence testing). In: Dasgupta A, ed. Beating Drug Tests and Defending Positive Results. Springer. 2026:125-143.

Gotlib J, Reiter A, Radia DH, Álvarez-Twose I, Deininger MW, George TI, Panse JP, Mital A, Pettit KM, Vannucchi AM, Platzbecker U, Hermine O, Elshoury A, Livideanu C, Mesa RA, Ustun C, Triggiani M, Dybedal I, Jurcic JG, Zanotti R, Oh ST, Yacoub A, Hexner EO, Bose P, Lee SG, Sperr WR, Griffiths EA, Butler M, Lübke J, Bidollari I, Lin HM, Rylova SN, Dimitrijević S, Muñoz-González JI, DeAngelo DJ. Efficacy and safety of avapritinib in advanced systemic mastocytosis: 4-year follow-up of the PATHFINDER study. Blood Adv. Published online Jan 2026.

Williams JF, Santoscoy Gutierrez JF, Nolazco JI, Steele GS, Burk KS, Hirsch MS, Rizzo NM. Clear cell adenocarcinoma of the urinary tract arising in a young man with the congenital malformation disorder Opitz syndrome: a case report. Int J Surg Pathol. Published online Jan 2026.

Lim AL, Miller BW, Fisher MA, Haygood MG, Barrows LR, Schmidt EW. Differential membrane lipid disruption by lipopeptide antibiotics, colistin and turnercyclamycins. Nat Commun. 2026;17(1):1880.

Mathison BA, Pritt BS. Arthropod Benchtop Reference Guide, 2nd Edition. College of American Pathologists; 2026.

Kirtek TJ, Chen W, Harris JC, Bagg A, Foucar K, Tam W, Orazi A, Hsi ED, Hasserjian RP, Wang SA, Ng DP, George TI, Shi M, Reichard KK, Symes E, Zhang X, Arber DA, Weinberg OK. Acute leukemias of ambiguous lineage with RUNX1 mutations show similar prognosis compared to acute myeloid leukemia with RUNX1 mutations: a study from the Bone Marrow Pathology Group. Am J Hematol. 2026;101(1):70-78.

Mathison BA, Couturier MR. Chapter 115: Intestinal Protozoa. In: Chung RT, Rubin DT, Wilcox M, eds. Sleisinger and Fordtran’s Gastrointestinal and Liver Disease, 12th Edition. Elsevier; 2025:1975-1987.

Smith K, Genesi BT, Boyd JM, Johnson-Davis KL. Improvements, challenges, and the investigation of two unknowns in arsenic urine speciation analysis by HPLC-ICP-MS: from development to post-implementation. Ther Drug Monit. Published online Dec 2025.

Kushnir MM, Kish-Trier E. Method development and validation. In: Zhang YZ, Garg U, eds. Practical Guide to Implementing Liquid Chromatography Mass Spectrometry in Clinical Laboratories. Springer; 2025:125-150.

Anderson C, Rawal M, Hymas W, Slev P, Bradley BT. Development of a dual-target measles virus PCR assay and testing trends at a national reference laboratory. Clin Microbiol. Published online Dec 2025.

Kushnir MM, Salihovic S, Bergquist J, Lind PM, Larsson A, Lind L. Environmental pollutants and adrenal steroids biosynthesis in elderly. Sci Total Environ. 2025;1011:181021.

Shean RC, Agarwal A, Rets AV. Unstable hemoglobin, a rare but significant cause of hemolytic anemia: recognition of peripheral smear findings is crucial for diagnosis. Int J Lab Hematol. Published online Dec 2025.

Shakir SM, McCall RK, Selvarangan R, Banerjee D, Goldstein Y, Lansang C, Bogh R, Remillard CV; RespDirect Clinical Study Group. Clinical evaluation of nasal swab specimens in VTM/UTM and RespDirect eSTM using the Panther Fusion SARS-CoV-2/Flu A/B/RSV assay. J Clin Virol. 2025;182:105908.

Johnson KB, Nelson R, Roy S. The evolving pharmacogenomic toolbox in anesthesiology. Anesth Analg. Published online Dec 2025.

Devlin PM, Allshouse AA, McMillin G, Chung JH, Grobman WA, Haas DM, Pippen JL, Parry S, Reddy UM, Saade GR, Simhan HN, Silver RM, Metz TD. Self-reported and biologic assessments of prenatal cannabis use: ancillary analysis of a prospective observational cohort. Subst Use Addctn J. 2025:29767342251389751.

Shean RC, Bennett ST. Clinical evaluation of a novel point-of-care hematology analyzer for complete blood count with differential. Int J Lab Hematol. Published online Dec 2025.

Pandya V. Transdermal GFR signals a new horizon in renal diagnostics. Clin Chem. 2025;71(12):1281-1282.

Manthei DM, Souers RJ, Melanson SEF, Genzen JR. Estimated glomerular filtration rate reporting from whole blood creatinine: a proficiency testing survey. Arch Pathol Lab Med. 2025;149(12):1060-1061.

Argani P, Fang H, Liu YJ, Baraban E, Gross JM. GLI1-altered mesenchymal tumor of the duodenum with a novel TNFAIP3::GLI1 gene fusion: report of a diagnostically challenging case associated with late metastasis. Genes Chromosomes Cancer. 2025;64(12):e70104.

Saadalla A, Doyle K, Moser K, Smock K. Determination of fibrinogen ratio cutoff limits using indirect reference interval methodology. Int J Lab Hematol. 2025;47(6):1171-1177.

Rowe S, Goubran M, Bustamante MS, Shyamsundar S, Austin B, McNicholas K, Blommers M, Shi J, Peterson LK, Sepiashvili L, Mattman A, Brandstadter JD, Fajgenbaum DC, Chen LYC. Ferritin, C‐reactive protein, and soluble CD25 distinguish TAFRO from HLH. Am J Hematol. 2025;100(12):2421-2425.

Kanack A, Mauch E, Roberge G, Splinter N, Gundabolu K, Wool GD, George G, Abou-Ismail MY, Smock KJ, Green DL, Coker J, Kohlhagen MC, Murray DL, Padmanabhan A. Platelet factor 4 antibody persistence and long-term pathogenicity in vaccine-induced immune thrombotic thrombocytopenia. medRxiv. 2025:2025.11.24.25340592.

Pritt BS, Gile GH, Bradbury RS, Mathison B, Zhao H, Mewara A. No evidence of human Lophonomas infection. Clinical Microbiology Newsletter. 2025;53:20-22.

Greenwall B, Reeder K, Anani WQ. Compound adsorption device in pathogen reduction technology removes multiple drugs from plasma components. Transfusion. Published online Nov 2025.

Ji Y, Brunk L, Bove B, Danyal K, Langman LJ, Mot N, Mroz P, Natowicz M, Reddi H, Shirts B, Smock K, Wool GD, Zhang BM, Moyer AM. Pharmacogenomic testing. Arch Pathol Lab Med. Published online Nov 2025.

Lewis RG, O'Shea JM, Pizzo L, Wen T, Fulmer ML, Zhao J, Verheijen J, Zhang C, Velinder M, Nicholas TJ, Boyden SE, Ward A, Baldwin EE, Andrews A, Ruiz JH, Marchetti M, Viskochil D, Carey JC, Bleyl SB, Butterfield RJ, Taliercio V, Botto LD, Mao R, Bayrak-Toydemir P; Undiagnosed Diseases Network. RNA sequencing provides functional insights and diagnostic resolution in previously unsolved rare disease cases. BMC Med Genomics. 2025;18(1):182.

Mathison BA, Knight K, Potts J, Walker JF, Markow F, Wood A, Bess D, Dixon K, Cahoon B, Hyman W, Couturier MR. Detection of protozoan and helminth parasites in concentrated wet mounts of stool using a deep convolutional neural network. J Clin Microbiol. 2025;63(11): e0106225.

Worth S, George TI, Shaheen DJ, Roche M, Vachhani P. Chronic anaphylaxis with indolent systemic mastocytosis: a case report. Case Rep Hematol. 2025;2025:9562195.

Paweletz CP, Forbes TD, Yee L, Heavey G, He H, He Z, Connors D, Stetson D, Keating S, Cole KD, Chen L, Pauly R, Bao H, Wu X, Pestano GA, Weaver AL, Kohli M, Hellwig S, Corner AS, Prantner AM, Wong SQ, Fox SB, Hewitt CA, Arnolda R, Jones GR, Craft J, McConechy M, Qahtani MA, Klemm F, Mohammad F, Sigman C, Liu L, Qiang Gan Q, Konigshofer Y, Garlick R, Chin E, Kelloff G, Williams PM, McCormack R, Karlovich C. Functional characterization and a real-world clinical laboratory pilot of the Foundation for the National Institutes of Health circulating tumor DNA quality control materials. JCO Precis Oncol. 2025;9:e2500245.

Spies NC. Embracing generative artificial intelligence as a support tool for clinical decision-making. Clin Chem. 2025;71(11):1178-1179.

Strelzer S, Klufas T, Solimine JF, Zhou AE, Grant-Kels JM. Reproductive ethics: defining the dermatologist's role. Clin Dermatol. 2025;S0738-081X(25)00293-7.

Shean R, Deshmukh N, Palmer M, Agarwal A, Rets A. Utility of molecular sequencing and hematologic parameters for diagnosis of α-thalassemia: a perspective of the national reference laboratory. Hemoglobin. 2025;49(6):414-420.

Fonseca EM, Fox S, Carey AL, Barker B, Marchetti M, Hirschi M, Hanson KE, Walter KS. Coccidioides genomes from low-incidence states reveal complex migration history across the western United States. Microbiol Spectr. 2025;13(12):e0182225.

Shean RC, Johnson-Davis KL. Broad-spectrum drug screening positivity rates in pediatrics and adults: the reference laboratory perspective. Ther Drug Monit. Published online Oct 2025.

Rets A, George TI. Diagnosing systemic mastocytosis: state of the art. Int J Lab Hematol. Published online Oct 2025.