Kyle C. Kurek, MD, MMSc

Professor, University of Utah School of Medicine

Specialties

• Pediatric tumor pathology
• Bone and soft tissue pathology
• Vascular anomalies
• Translational research
• Molecular genomics

Education

• Medical Degree—Warren Alpert Medical School of Brown University
• Master of Medical Science—Warren Alpert Medical School of Brown University
• Research Fellowship—Molecular Biology, University of Oxford, UK
• Internship—Pediatrics, University of Wisconsin Madison
• Residency—Anatomic and Clinical Pathology, Brown University
• Fellowship—Pediatric and Perinatal Pathology, Harvard University
• Postdoctoral Fellowship—Molecular Genetics, Harvard University

Current/Past Roles

• Board of Directors, Society for Pediatric Pathology
• Past Chief, Pathology and Lab Medicine, Alberta Children’s Hospital/University of Calgary
• Past President, Association of Clinical Scientists

Certification/Affiliations

• American Board of Pathology (Anatomic and Clinical Pathology)

Research Interests

• Molecular genomics and somatic mosaicism
• Vascular anomalies and related disorders
• Pediatric sarcomas
• Neurocristopathies

Awards

• Haffenreffer Outstanding Trainee Award, Brown University
• Ramzi Cotran Pathology Teaching Award, Harvard University
• Young Clinical Scientist Award, Association of Clinical Scientists
• Neustein Innovation Award, Society for Pediatric Pathology
• Lotte Strauss Award, Society for Pediatric Pathology
• Brown Award, Paediatric Pathology Society (Europe)
• Sunderman Clinical Scientist Award, Association of Clinical Scientists

Recent Publications

• Slattery SM, Perez IA, Ceccherini I,  et al. Transitional care and clinical management of adolescents, young adults, and suspected new adult patients with congenital central hypoventilation syndrome. Clin Auton Res. 2023;33(3):231-249.
• Khaytin I, Victor AK, Barclay SF,  et al. Rapid-onset obesity, hypothalamic dysfunction, hypoventilation, and autonomic dysregulation (ROHHAD): a collaborative review and current understanding. Clin Auton Res. 2023;33(3):251-268.
• Perez-Atayde AR, Debelenko L, Al-Ibraheemi A,  et al. Kaposiform lymphangiomatosis: pathological aspects in 43 patients. Am J Surg Pathol. 2022;46(7): 963-976.
• Park PC, Kurek KC, DeCoteau J,  et al. CAP-ACP workload model for advanced diagnostics in precision medicine. Am J Clin Pathol. 2022;158(1):105-111.
• Wright JR Jr, Chan S, Morgen EK,  et al. Workload measurement in subspecialty placental pathology in Canada. Pediatr Dev Pathol. 2022;25(6):604-610.
• Ceccherini I, Kurek KC, Weese-Mayer DE. Developmental disorders affecting the respiratory system: CCHS and ROHHAD. Handb Clin Neurol. 2022;189:53-91.
• Slack JC, Kurek KC, Fraulin FOG,  et al. Cutaneous B-cell pseudolymphoma (lymphocytoma cutis) of the earlobe: a poorly recognized complication of ear piercing in children. Fetal Pediatr Pathol. 2022;41(3):486-492.
• Slack JC, Bründler MA, Chang CA,  et al. Bilateral nephroblastic tumors and a complex renal vascular anomaly in a patient with a mosaic RASopathy: novel histopathologic features and molecular features. Pediatr Dev Pathol. 2021;24(3):235-240.
• AlTeneiji M, Brundler MA, Noseworthy M,  et al. Unilateral congenital pulmonary lymphangiectasis presenting with pneumonia and an NRAS variant. Pediatr Pulmonol. 2021;56(7):2374-2376.
• Slack JC, Bründler MA, Nohr E,  et al. Molecular alterations in pediatric fibroblastic/myofibroblastic tumors: an appraisal of a next-generation sequencing assay in a retrospective single centre study. Pediatr Dev Pathol. 2021;24(5):405-421.
• Chang CA, Perrier R, Kurek KC, et al. Novel findings and expansion of phenotype in a mosaic RASopathy caused by somatic KRAS variants. Am J Med Genet A. 2021;185(9):2829-2845.
• Gharial J, Ganesh A, Curtis C, et al. Neuroimaging and pathology findings associated with rapid onset obesity, hypothalamic dysfunction, hypoventilation, and autonomic dysregulation (ROHHAD) syndrome. J Pediatr Hematol Oncol. 2021;43(4):e571-576.
• Bakker A, Slack JC, Caragea M et al. Adipocyte-rich CTNNB1-mutated intramuscular Gardner fibroma progressing to desmoid fibromatosis. Pediatr Dev Pathol. 2021;24(1):62-67.
• Barclay SF, Inman KW, Luks VL, et al. A somatic activating NRAS variant associated with kaposiform lymphangiomatosis. Genet Med. 2019;21(7):1517-1524.
• Maximov VV, Akkawi R, Khawaled S, et al. MiR-16-1-3p and miR-16-2-3p possess strong tumor suppressive and antimetastatic properties in osteosarcoma. Int J Cancer. 2019;145(11):3052-3063.
• Tachibana N, Touahri Y, Dixit R, et al. Hamartoma-like lesions in the mouse retina: an animal model of Pten hamartoma tumour syndrome. Dis Model Mech. 2018;11(5):dmm031005.
• de Champlain K, Kurek KC, Yunker WK. Novel presentation of cranial rasciitis of the mandible: case report and literature review. Int J Pediatr Otorhinolaryngol. 2018;115:33-37.