Filippo Ingoglia, PhD

Filippo Ingoglia, PhD

Medical Director: Biochemical Genetics


Assistant Professor (Clinical), University of Utah School of Medicine


Clinical biochemical genetics


  • Master’s Degree—Biology and Biomedical Application, University of Parma
  • Doctorate—Molecular Medicine, University of Parma
  • Postdoctoral Fellowship—Clinical Biochemical Genetics, University of Utah School of Medicine, ARUP Laboratories
  • Research Fellow—General Pathology, University of Parma
  • Research Fellow—Molecular Medicine, University of Utah School of Medicine


  • American Board of Medical Genetics and Genomics (Clinical Biochemical Genetics)

Research Interests

  • Development of a new method for measuring guanidino compounds using an ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) system (Waters Acquity UPLC solvent/sample manager; Waters Xevo TQS tandem mass spectrometer).
  • Collaborating on a research project focused on evaluation and development of methods to determine effectiveness of potential therapeutic agents for the treatment of guanidinoacetate methyltransferase (GAMT) deficiency.
  • Collaborating with the Mass Spec group at ARUP Laboratories on a targeted metabolomics feasibility project using a liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF-MS) system.


  • 2019 Takeda Pharmaceuticals/ACMG Foundation Next Generation Fellowship Award, April 2019.

Recent Publications

Ingoglia F, et al. Creatine metabolism in patients with urea cycle disorders. Mol Genet Metab Rep. 2021;29:100791.

Rotoli BM, et al. Analysis of LPI-causing mutations on y+LAT1 function and localization. Orphanet J Rare Dis. 2019;14(1):63.

Rotoli BM, et al. Downregulation of SLC7A7 triggers an inflammatory phenotype in human macrophages and airway epithelial cells. Front Immunol. 2018;9:508.

Barilli A, et al. Gluten peptides drive healthy and celiac monocytes toward an M2-like polarization. J Nutr Biochem. 2018;54:11–17.

Ingoglia F. Functional and molecular analysis of organic cation transporters (OCTs and OCTNs) in human airway epithelial cells and macrophages. Doctoral Thesis, Editor: University of Parma, March 2017. ©Filippo Ingoglia, 2017.