ARUP's Laboratory Test Directory

Dexamethasone, Serum or Plasma by LC-MS/MS : 2003248

Mnemonic: DEXA TMS

Methodology: Liquid Chromatography-Tandem Mass Spectrometry
Performed: Mon, Thu
Reported: 1-6 days
Specimen Required: Patient Prep: It is recommended that the specimen be collected between 6-11 a.m.

Collect: Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium heparin).

Specimen Preparation: Separate serum or plasma from cells ASAP or within 2 hours of collection. Transport 1 mL serum or plasma. (Min: 0.5 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Room temperature specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months

Reference Interval:
Adults baseline: Less than 50 ng/dL
8:00 AM draw following 1 mg dexamethasone between 11:00 pm and 12:00 am the previous evening: 140 - 295 ng/dL
8:00 AM draw following 8 mg dexamethasone (4 x 2 mg doses) between 11:00 pm and 12:00 am the previous evening: 1600 - 2850 ng/dL
Interpretive Data:

See Compliance Statement B: www.aruplab.com/CS
CPT Code(s): 80299