ARUP's Laboratory Test Directory

EGFR Mutation Detection by PCR and Fragment Analysis : 2002440

Mnemonic: EGFR PCR

Methodology: Polymerase Chain Reaction/Fragment Analysis
Performed: Sun-Sat
Reported: 10-12 days
Specimen Required: Collect: Tumor tissue.

Storage/Transport Temperature: Paraffin-embedded, formalin-fixed tissue block, or 5 unstained 5µm slides at 20-25°C. (Min: 3 slides) Protect paraffin block from excessive heat. Ship in cooled container during summer months. Include surgical pathology report.

Unacceptable Conditions: No tumor in tissue. Frozen specimens and specimens fixed/processed in alternative fixatives (alcohol, Prefer®)

Stability (collection to initiation of testing): Ambient: Indefinitely; Refrigerated: Acceptable; Frozen: Unacceptable
Interpretive Data: Refer to report

Please refer to Statement B in the Compliance Statements section in the front of the Laboratory Test Directory.
CPT Code(s): 88381 Microdissection; 83907 Lysis; 83898 Amplification; 83892 Digestion; 83909 Separation and identification; 83896 x2 Nucleic acid probes; 83912 Interpretation and report - Additional CPT code modifiers may be required for procedures performed to test oncologic or inherited disorders.
Cross References: ERBB1, Erlotinib Responsiveness in NSCLC, EGFR Mutation Analysis, Gefitinib Responsiveness in NSCLC, EGFR Mutation Analysis, IRESSA Responsiveness in NSCLC, EGFR Mutation Analysis, NSCLC or Non Small-cell Lung Cancer, Tarceva Responsiveness in NSCLC, EGFR Mutation Analysis
 
 

 

 

 
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