ARUP's Laboratory Test Directory

Porphyrins, Fractionation & Quantitation, Urine : 2002058

Mnemonic: PORURINE

Methodology: High Performance Liquid Chromatography
Performed: Sun, Tue-Sat
Reported: 1-4 days
Specimen Required: Collect: 24-hour or random urine. Refrigerate 24-hour specimens during collection.

Storage/Transport Temperature: 4.5 mL aliquot, frozen. (Min: 2 mL) Submit specimen in an ARUP Amber Transport Tube.

Remarks: The most important aspect of specimen preservation is adequate refrigeration during collection, storage, and transport. Protect from light during collection, storage, and shipment. Record total volume and collection time interval on transport tube and test request form.

Stability (collection to initiation of testing): Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month
Reference Interval:
 
Test Number Components Reference Interval
 Uroporphyrin 0-4 µmol/mol crt
 Heptacarboxylate Porphyrin 0-2 µmol/mol crt
 Coproporphyrin I 0-6 µmol/mol crt
 Coproporphyrin III 0-14 µmol/mol crt
0020473Creatinine, 24-Hour Urine  
 
Male Female
3-8 years:      140-700 mg/d
9-12 years:    300-1300 mg/d
13-17 years:  500-2300 mg/d
18-50 years:  1000-2500 mg/d
51-80 years:  800-2100 mg/d
81 years and older: 600-2000 mg/d 		3-8 years:      140-700 mg/d
9-12 years:    300-1300 mg/d
13-17 years:  400-1600 mg/d
18-50 years:  700-1600 mg/d
51-80 years:  500-1400 mg/d
81 years and older: 400-1300 mg/d

Note: Urine porphyrins are useful for the evaluation of cutaneous photosensitivity to exclude porphyria cutanea tarda (PCT). Evaluation of neurologic and/or psychiatric symptoms associated with acute porphyrias such as acute intermittent porphyria (AIP) requires urine porphobilinogen (PBG) testing. Refer to Porphobilinogen (PBG), Urine (0080260). 
CPT Code(s): 84120
Cross References: Porphyrins, Fractionated, Quantitative, 24-Hour Urine
 
 

 

 

 
All ARUP Sites:        www.aruplab.com     ·     www.arupconsult.com     ·     www.arup.utah.edu     ·     www.childx.org     ·     www.utahblood.org