ARUP's Laboratory Test Directory

Cardiolipin Antibody, IgA : 0098358

Mnemonic: CARDIO IGA

Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Wed, Sat
Reported: 1-2 days
Specimen Required: Collect:  One 4 mL serum separator tube.

Transport:  1 mL serum at 2-8°C.  (Min: 0.5 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport:  0.15 mL serum at 2-8°C.

Remarks:  Separate serum from cells ASAP.

Unacceptable Conditions:  Plasma and other body fluids.  Heat-inactivated, hemolyzed, lipemic, or contaminated specimens.

Stability:  After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
< 12 APL: Negative
12-15 APL: Inconclusive
> 15 APL: Positive
Interpretive Data: APL = IgA phospholipid units

Some recent studies indicate that elevated levels of IgA class anticardiolipin antibodies are found in patients with systemic lupus erythematosus (SLE) and related disorders.  In these studies, IgA values are higher in patients with vascular complications and thrombocytopenia.
CPT Code(s): 86147
 
 

 

 

 
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