Lymphocyte Antigen & Mitogen Proliferation Panel : ARUP Lab Tests

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Lymphocyte Antigen & Mitogen Proliferation Panel : 0096056

Time Sensitive

Mnemonic: LAM

Methodology:	Cell Culture
Performed:	Tue-Fri
Reported:	9-10 days
Specimen Required:	Patient Prep: Send control with patient specimen. Collect: One 10 mL yellow (ACD Solution A) and a normal control in one 10 mL yellow (ACD Solution A) from a healthy unrelated individual. Storage/Transport Temperature: 10 mL whole blood and 10 mL normal control in original collection tubes at 20-25°C. (Min: 7 mL whole blood and 7 mL normal control; Infant min: 3 mL whole blood and 7 mL normal control). LIVE LYMPHOCYTES REQUIRED. CRITICAL AMBIENT. Do not refrigerate or freeze. Remarks: Patient and control samples must be collected within 48 hours of test performance. Unacceptable Conditions: Refrigerated or frozen samples or samples in transport longer than 48 hours. Stability (collection to initiation of testing): Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable

Reference Interval: By report
Interpretive Data:	Phytohemagglutinin, concanavalin A, pokeweed mitogen, Candida antigen, and tetanus antigen are tested independently in lymphocyte culture. Lymphocyte proliferation in response to these mitogens and antigens is determined by³H-thymidine incorporation. Results are reported as the counts per minute (CPM) mitogen or antigen stimulated versus a control culture and a stimulation index (SI) which represents the ratio of CPM of the stimulated lymphocytes to the mean CPM of the unstimulated control. Please refer to Statement B in the Compliance Statements section in the front of the Laboratory Test Directory.
Note:	Interpretation comparing the patient results to the client normal control and the laboratory control will be provided by the medical director.
CPT Code(s):	86353 x5 Lymphocyte transformation
Cross References:	Antigen & Mitogen Proliferation Panel, Lymphocytes

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