ARUP's Laboratory Test Directory

Estradiol, Males, Children or Postmenopausal Females by Tandem Mass Spectrometry : 0093247

Mnemonic: ESDIOL TMS

Ordering Recommendation: Suitable for measurement of estradiol in men, children, or postmenopausal women. Preferred test for adult premenopausal women is Estradiol, Adult Premenopausal Female, Serum or Plasma (0070045).
Methodology: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed: Sun-Sat
Reported: 1-4 days
Specimen Required: Collect: Serum separator tube, lavender (EDTA), pink (K2EDTA) or green (sodium or lithium heparin).

Specimen Preparation: Separate serum or plasma from cells within 2 hours after collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min 0.3 mL) Indicate age and sex of patient on test request form AND specimen tube.

Storage/Transport Temperature: Refrigerated.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 1 week; Frozen: 1 month
Reference Interval:
Reference Intervals for Estradiol-Children
Tanner Stages
I
II
III
IV and V 		Males
less than 8 pg/mL
less than 10 pg/mL
1-35 pg/mL
3-35 pg/mL 		Females
less than 56 pg/mL
2-133 pg/mL
12-277 pg/mL
2-259 pg/mL
Age Group
7-9
10-12
13-15
16-17 		Males
less than 7 pg/mL
less than 11 pg/mL
1-36 pg/mL
3-34 pg/mL 		Females
less than 36 pg/mL
1-87 pg/mL
9-249 pg/mL
2-266 pg/mL

Reference Intervals for Estradiol-Adults
Females 18 Years and Older Males 18 years and Older
Pre-menopausal:
Early Follicular: 30-100 pg/mL
Late Follicular: 100-400 pg/mL
Luteal: 50-150 pg/mL 		10-42 pg/mL
Postmenopausal: 2-21 pg/mL

Interpretive Data:

See Compliance Statement B: www.aruplab.com/CS
CPT Code(s): 82670
Cross References: Estradiol (E2) (Estradiol, Males, Children or Postmenopausal Females, by Tandem Mass Spectrometry)