ARUP's Laboratory Test Directory

0093098: Dengue Fever Virus Antibody, IgM

Test Mnemonic: DEN M
Methodology: Enzyme-Linked Immunosorbent Assay

Performed: Mon

Reported: 1-8 days

Specimen Required:  
Collect: One 4 mL SST.

Transport: 1 mL serum at 2-8°C. (Min: 0.2 mL)  Submit specimen in an ARUP Standard Transport Tube.

 

Pediatric Collection/Transport: 0.1 mL serum at 2-8°C.

Remarks: Separate serum from cells ASAP.  Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.  Please mark specimen plainly as "acute or convalescent."

Unacceptable Conditions: Severely lipemic, contaminated, heat-inactivated, or hemolyzed specimens.

Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval:
0.89 IV or less: Negative - No significant level of detectable dengue fever virus IgM antibody.
0.90-1.10 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
1.11 IV or greater: Positive-IgM antibody to dengue fever virus detected, which may indicate a current or recent infection.  However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.

Interpretive Data:
Patients in the early stage of dengue fever virus infection may not have detectable IgG antibodies, as the IgG response may take several weeks to develop.  In the absence of detectable IgG, testing for IgM class antibody is strongly recommended. 

Please refer to Statement D in the Compliance Statements section in the front of the Laboratory Test Directory.



CPT Code(s):
86790

 

 

 
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