ARUP's Laboratory Test Directory

Treponema pallidum (VDRL), Serum with Reflex to Titer : 0093093

Mnemonic: VDRL SERU

Ordering Recommendation: Acceptable initial screening test for syphilis. May use to confirm reactive treponemal test (eg, EIA, CIA) if using so-called reverse algorithm testing. Acceptable test for monitoring treatment response in established syphilis.
Methodology: Semi-Quantitative Flocculation
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Collect: Plain red or serum separator tube.

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube (Min: 0.25 mL)

Storage/Transport Temperature: Refrigerated

Unacceptable Conditions: CSF or other body fluids. Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval:
 
Test Number Components Reference Interval
 Treponema pallidum (VDRL), Serum Nonreactive
 Treponema pallidum (VDRL) Titer, Serum < 1:2

Interpretive Data: VDRL as a screening test is less sensitive than RPR.
Note: If VDRL is weakly reactive or reactive, then a titer will be added.  Additional charges apply.
CPT Code(s): 86592; if reflexed, add 86593
Cross References: VDRL, Serum