ARUP's Laboratory Test Directory

Drugs of Abuse Panel, Meconium - Screen with Reflex to Confirmation/Quantitation : 0092516
[ image for: Meconium Drug Screen Detectable Analytes and Trade Names]
Meconium Drug Screen Detectable Analytes and Trade Names
  


Mnemonic: MEC 9

Methodology: Enzyme Immunoassay/Gas Chromatography-Mass Spectrometry/Liquid Chromatography-Tandem Mass Spectrometry
Performed: Sun-Sat
Reported: 1-4 days
Specimen Required: Collect:  Meconium. All meconium (blackish material) excreted until milk/formula based stool (yellow-green) appears.

Storage/Transport Temperature:  All meconium available (4 g is preferred) at 20-25°C. (Min: 2 g or 3/4 inch cube on each side)

Stability (collection to initiation of testing):  Ambient: 1 week; Refrigerated: 3 months; Frozen: 1 year
Reference Interval:
 
Drugs Covered and Cutoff Concentrations
Drug Screen Confirmation
Marijuana 30 ng/g 5 ng/g
Cocaine 30 ng/g 20 ng/g
Opiates 30 ng/g 2 ng/g
Phencyclidine 15 ng/g 10 ng/g
Amphetamines 30 ng/g 20 ng/g
Barbiturates 75 ng/g 50 ng/g
Methadone 40 ng/g 10 ng/g
Benzodiazepines 75 ng/g 20 ng/g
Propoxyphene 75 ng/g 10 ng/g

Interpretive Data: Meconium begins to form between the 12th and 16th week of gestation. Meconium drug testing can detect maternal drug use during the last 4 to 5 months of pregnancy. A negative result does not exclude the possibility that a mother used drugs during pregnancy. Detection of drug use depends on the quantity and quality of the specimen tested as well as the pattern and frequency of drug(s) used by mother. The concentration at which the screening test can detect a drug or metabolite varies within a drug class. Specimens for which drugs or drug classes are detected by the screen are reflexed to a second, more specific technology (GC/MS and/or LC-MS/MS). The concentration value must be greater than or equal to the cutoff to be reported as positive. Although not likely, the presence of drugs administered during labor and delivery may be detected in meconium. Interpretive questions should be directed to the laboratory.

For medical purposes only; not valid for forensic use.
Note: Screen-positive specimens are automatically confirmed by GC/MS and/or LC-MS/MS; additional charges may apply.
CPT Code(s): 80101 x9 Screen; if positive add appropriate CPT code for drug confirmed: 82542 Marijuana; 82520 Cocaine; 83925 Opiates; 83992 Phencyclidine; 82145 Amphetamines; 82205 Barbiturates; 83840 Methadone; 80154 Benzodiazepine; 83925 Propoxyphene
Cross References: MEC 5, MEC 7
 
 

 

 

 
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