ARUP's Laboratory Test Directory

Nicotine & Metabolites, Urine : 0092356

Mnemonic: NICOTINEUR

Methodology: Liquid Chromatography-Tandem Mass Spectrometry
Performed: Sun-Sat
Reported: 1-4 days
Specimen Required: Collect:  Random urine.

Transport:  5 mL urine with no additives or preservatives at 20-25°C. (Min: 2 mL) Submit specimen in ARUP Standard Transport Tube(s).

Unacceptable Conditions:  Specimens exposed to repeated freeze/thaw cycles.

Stability:  Ambient: 10 days; Refrigerated: 10 days; Frozen: 8 months
Reference Interval:
 
 Unexposed non-tobacco user Passive exposure Abstinent user for greater than 2 weeks Active tobacco product use
Nicotine Less than 2 ng/mL Less than 20 ng/mL Less than 30 ng/mL 1000-5000 ng/mL
Cotinine Less than 5 ng/mL Less than 20 ng/mL Less than 50 ng/mL 1000-8000 ng/mL
3-OH-Cotinine Less than 50 ng/mL Less than 50 ng/mL Less than 120 ng/mL 3000-25000 ng/mL
Nornicotine Less than 2 ng/mL Less than 2 ng/mL Less than 2 ng/mL 30-900 ng/mL
Anabasine Less than 3 ng/mL Less than 3 ng/mL Less than 3 ng/mL 3-500 ng/mL*
Adapted from Clinical Chemistry 2002;48:1460-71.

Interpretive Data: The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

For medical purposes only; not valid for forensic use.
CPT Code(s): 83887
 
 

 

 

 
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