Prazepam (Assayed as Nordiazepam) : ARUP Lab Tests

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Prazepam (Assayed as Nordiazepam) : 0090672

Mnemonic: PRAZE

Methodology:	Quantitative Gas Chromatography
Performed:	Sun, Tue, Thu
Reported:	1-4 days
Specimen Required:	Collect: Plain red. Also acceptable: Lavender (EDTA), pink (K₂EDTA), green (sodium heparin), gray (sodium fluoride/potassium oxalate). Avoid use of separator tubes and gels. Specimen Preparation: Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL) Storage/Transport Temperature: Refrigerated. Stability (collection to initiation of testing): After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: 2 months

Reference Interval: Dose-Related Range: Nordiazepam: 0.60-1.50 µg/mL Toxic: > 2.00 µg/mL
Interpretive Data:	Prazepam is not detected in serum due to its rapid metabolism to nordiazepam. Prazepam dosage to achieve therapeutic results is not well defined. Following oral administration of 20 mg, three times a day for three days, plasma concentrations of nordiazepam averaged 0.8 µg/mL, 12 hours after final dose.
CPT Code(s):	80154
Cross References:	Centrax (Prazepam (Assayed as Nordiazepam)), Verstran (Prazepam (Assayed as Nordiazepam))

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