ARUP's Laboratory Test Directory

Lamotrigine : 0090177

Mnemonic: LAMOT

Methodology: High Performance Liquid Chromatography
Performed: Mon-Fri
Reported: 1-4 days
Specimen Required: Collect:  One 5 mL plain red. Also acceptable: lavender (EDTA), pink (K2EDTA), green (sodium heparin), gray (sodium fluoride/potassium oxalate).

Transport:  1 mL serum or plasma at 2-8°C. (Min: 0.6 mL) Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport:  0.6 mL serum or plasma at 2-8°C.

Remarks:  Separate serum or plasma from cells and refrigerate ASAP. Avoid use of separator tubes and gels.

Stability:  After separation from cells: Ambient: 1 month; Refrigerated: 6 weeks; Frozen: 6 months
Reference Interval:
Therapeutic Range: Not well established.
Interpretive Data: The proposed therapeutic range for seizure control is 3-14 µg/mL.  Concentrations that exceed 15 µg/mL may contribute to adverse effects.  Pharmacokinetics varies widely, particularly with co-medications and/or compromised renal function.
CPT Code(s): 80299
 
 

 

 

 
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