ARUP's Laboratory Test Directory
| 0090177: Lamotrigine |
| Test Mnemonic: LAMOT | |
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Methodology: High Performance Liquid Chromatography
Performed: Mon-Fri Reported: 1-4 days |
| Specimen Required: | |
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Collect: One 5 mL plain red. Also acceptable: lavender (EDTA), pink (K2EDTA), green (sodium heparin), gray (sodium fluoride/potassium oxalate).
Transport: 1 mL serum or plasma at 2-8°C. (Min: 0.6 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.6 mL serum or plasma at 2-8°C. Remarks: Separate serum or plasma from cells and refrigerate ASAP. Avoid use of separator tubes and gels. Stability: After separation from cells: Ambient: 1 month; Refrigerated: 6 weeks; Frozen: 6 months |
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| Reference Interval: |
| Therapeutic Range: Not well established. |
| Interpretive Data: | |
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The proposed therapeutic range for seizure control is 3-14 µg/mL. Concentrations that exceed 15 µg/mL may contribute to adverse effects. Pharmacokinetics varies widely, particularly with co-medications and/or compromised renal function.
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| CPT Code(s): | |
| 80299 |