ARUP's Laboratory Test Directory
| 0081135: Oligoclonal Bands in CSF & Serum |
| Test Mnemonic: OLIGOB | |
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Methodology: Isoelectric Focusing/Immunofixation
Performed: Mon, Wed, Fri Reported: 2-4 days |
| Specimen Required: | |
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Collect: CSF and one 5 mL SST.
Transport: 1.5 mL CSF and 1 mL serum at 2-8°C. (Min: 0.7 mL CSF and 0.5 mL serum) Submit serum specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.7 mL CSF and 0.5 mL serum at 2-8°C. Remarks: Allow serum to clot completely at room temperature. Separate serum from cells ASAP. Serum specimen should be drawn within 48 hours of CSF collection. Specimens must be assayed together for interpretation. Stability: Ambient: 8 hours; Refrigerated: 8 days; Frozen: 1 year |
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| Reference Interval: | |||||||||
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| Note: | |
| This test reports only the number of oligoclonal bands. A patient is considered positive for CSF oligoclonal bands if there are two or more bands in the CSF immunoglobulin region that are not present in the serum. In order to confirm local production of oligoclonal IgG in CSF, a matched serum sample is required. Oligoclonal bands present in CSF, but not in serum, indicate central nervous system production. Oligoclonal bands are performed using isoelectric focusing and immunofixation. |
| CPT Code(s): | |
| 83916 |