ARUP's Laboratory Test Directory
| 0080462: Cancer Antigen 125 |
| Test Mnemonic: CA125 | |
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Methodology: Electrochemiluminescent Immunoassay
Performed: Sun-Sat Reported: Within 24 hours |
| Specimen Required: | |
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Collect: One 4 mL SST or PST. Also acceptable: green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA).
Transport: 1 mL serum or plasma at 2-8°C. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.2 mL serum or plasma at 2-8°C. Remarks: Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP. Unacceptable Conditions: Grossly hemolyzed specimens. Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 3 months |
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| Reference Interval: |
| 0-35 U/mL |
| Interpretive Data: | |
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The Roche Modular E170 CA 125 electrochemiluminescent immunoassay is used. Results obtained with different assay methods or kits cannot be used interchangeably. The CA 125 assay is used as an aid in monitoring response to therapy for patients with epithelial ovarian cancer. Serial testing for patient CA 125 values should be used in conjunction with other clinical methods for monitoring ovarian cancer. Patients with confirmed ovarian carcinoma may have pretreatment CA 125 assay values in the same range as healthy individuals. Elevations may be observed in patients with nonmalignant disease. For these reasons, a CA 125 assay value, regardless of level, should not be interpreted as absolute evidence of the presence or absence of malignant disease.
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| CPT Code(s): | |
| 86304 |