ARUP's Laboratory Test Directory

Renin Activity : 0070105

Mnemonic: RENIN

Methodology: Radioimmunoassay
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Collect:  One 5 mL lavender (EDTA) or pink (K2EDTA).

Transport:  2 mL plasma, frozen. (Min: 1.2 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport:  0.6 mL plasma, frozen.

Remarks:  CRITICAL FROZEN.  Separate specimens must be submitted when multiple tests are ordered.  Separate plasma from cells and freeze immediately. If an upright specimen is collected, patient should be upright (seated or standing) for at least two hours.  Do not refrigerate.  Do not collect in refrigerated tubes.

Unacceptable Conditions:  Serum.  Specimens collected in heparin, citrate, or oxalate.  Refrigerated specimens. Hemolyzed specimens.

Stability:  After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month
Reference Interval:
Adult, normal sodium diet:
  Supine: 0.2-1.6 ng/mL/hr
  Upright: 0.5-4.0 ng/mL/hr
Newborn (1-7 days): 2.0-35.0 ng/mL/hr
Cord blood: 4.0-32.0 ng/mL/hr
Children, normal sodium diet, supine:
  1-12 months: 2.4-37.0 ng/mL/hr
  13 months-3 years: 1.7-11.2 ng/mL/hr
  4-5 years: 1.0-6.5 ng/mL/hr
  6-10 years: 0.5-5.9 ng/mL/hr
  11-15 years: 0.5-3.3 ng/mL/hr
Interpretive Data: Plasma renin activity measures enzyme ability to convert angiotensinogen to angiotensin I and is limited by the availability of angiotensinogen. Plasma renin activity is not an accurate indicator of enzyme activity when angiotensinogen is decreased.
CPT Code(s): 84244
 
 

 

 

 
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