Reference Interval:
Effective September 26, 2011
Male:
0-6 years: 0.10-6.20 ng/mL
7-17 years: 0.03-11.00 ng/mL
18 years and older: 0.01-3.00 ng/mL
Female:
0-6 years: 0.10-6.20 ng/mL
7-17 years: 0.05-17.30 ng/mL
18 years and older: 0.01-8.00 ng/mL
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| Interpretive Data: |
Growth hormone stimulation tests should induce a peak of greater than 5 ng/mL in children and greater than 4 ng/mL in adults; lower values suggest growth hormone deficiency. For children, some experts consider values of 5-7 ng/mL equivocal and only peak values of greater than 7 ng/mL as truly normal.
For suppression testing, normal subjects have growth hormone concentrations of less than 0.8 ng/mL within 2 hours of ingestion of a 75 or 100 gram glucose dose. Patients with acromegaly fail to show normal suppression.
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| Note: |
The Growth Hormone assay is now standardized to the Recombinant Second International Standard (IS) 98/574. Growth hormone results read approximately 25% lower than with the previous standards (1st IS 80/505). Reference ranges have also been modified according to the assay manufacturer.
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| CPT Code(s): |
83003
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Cross References: |
Human Growth Hormone (Growth Hormone, 0 Minutes) |