ARUP's Laboratory Test Directory

Aldosterone/Renin Activity Ratio : 0070073

Mnemonic: A/RA

Methodology: Radioimmunoassay
Performed: Sun-Sat
Reported: 1-5 days
Specimen Required: Patient Prep:  Supine:  1.  Sample obtained 8-9 a.m.; 2. Fasting starting at midnight; 3. Normal sodium diet (100-200 mEq/day) for at least three days.; 4.  Receiving no medications known to affect renin-aldosterone system. Upright: 1.  Samples obtained before noon (after at least two hours in upright position),; 2.  Normal sodium diet (100-200 mEq/day) for at least three days.; 3. Receiving no medications known to affect renin-aldosterone system.    Contact Medical Director for more information.

Collect:  One 6 mL plastic serum separator tube and one 5 mL lavender (EDTA) or pink (K2EDTA).

Storage/Transport Temperature:  1 mL serum and 1 mL plasma  (Min: 0.5 mL serum and 0.6 mL plasma), frozen.  Submit specimens in an ARUP Standard Transport Tube.

Remarks:  CRITICAL FROZEN.  Separate specimens must be submitted when additional tests are ordered. Do not refrigerate.  Do not collect in refrigerated tubes.  Separate plasma from cells ASAP and freeze.

Unacceptable Conditions:  Refrigerated plasma.

Stability (collection to initiation of testing):  After separation from cells: Ambient: 4 hours; Refrigerated: Unacceptable; Frozen: 1 month
Reference Interval:
 
Test Number Components Reference Interval
0070015Aldosterone, Serum  
 
Age Posture Unspecified Supine Upright
0-6 days 5.0-102.0 ng/dL   
1-3 weeks 6.0-179.0 ng/dL   
1-11 months 7.0-99.0 ng/dL   
1-2 years 7.0-93.0 ng/dL   
3-10 years 4.0-44.0 ng/dL   
11-14 years 4.0-31.0 ng/dL   
15 years and older 31.0 ng/dL or less 16.0 ng/dL or less 4.0-31.0 ng/dL
0070105Renin Activity  
 
Adult, normal sodium diet Children, normal sodium diet, supine:  Children, normal sodium diet, upright: 
Supine: 0.2-1.6 ng/mL/hr
Upright: 0.5-4.0 ng/mL/hr 		Newborn (1-7 days): 2.0-35.0 ng/mL/hr
Cord blood: 4.0-32.0 ng/mL/hr
1-12 months: 2.4-37.0 ng/mL/hr
13 months-3 years:1.7-11.2 ng/mL/hr
4-5 years:1.0-6.5 ng/mL/hr
6-10 years: 0.5-5.9 ng/mL/hr
11-15 years: 0.5-3.3 ng/mL/hr 		0-3 years: Not Available
4-5 years: Less than or equal to 15 ng/mL/hr
6-10 years: Less than or equal to 17 ng/mL/hr
11-15 years: Less than or equal to 16 ng/mL/hr
 Aldosterone/Renin Activity Calculation < 25
An Aldosterone/Renin Activity Ratio of greater than 25 is suggestive of hyperaldosteronism.
 
CPT Code(s): 82088 Aldosterone, 84244 Renin activity
 
 

 

 

 
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