ARUP's Laboratory Test Directory
| 0063999: Antimicrobial Susceptibility - Extended Spectrum Beta Lactamase |
| Test Mnemonic: MA ESBL | |
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Methodology: Disk Diffusion
Performed: Sun-Sat Reported: 1-2 days |
| Specimen Required: | |
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Collect: Actively growing E. coli, Klebsiella species, or Proteus mirabilis in pure culture, on agar slant or in bacterial transport media. Indicate isolate identification and specimen source. Proteus mirabilis is tested only when isolated from a significant source (e.g., blood).
Transport: Isolate in pure culture in a sealed container at 20-25°C. Submit specimen according to Biological Substance, Category B, shipping guidelines. Pediatric Collection/Transport: Submit specimen according to Biological Substance, Category B, shipping guidelines. Unacceptable Conditions: Nonviable organisms or mixed cultures. Stability: Ambient: 1 week; Refrigerated: 2 days; Frozen: Unacceptable |
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| Reference Interval: |
| Negative |
| Interpretive Data: | |
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Currently there are no CLSI guidelines for testing organisms other than E. coli, Klebsiella spp., and Proteus mirabilis for the presence of ESBL activity. The CLSI-approved method does not rule out resistance by other mechanisms.
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| Note: | |
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The following agents are tested with and without clavulanic acid: ceftazidime and cefotaxime. An additional handling fee will be billed for all organisms submitted that are not in pure culture as indicated in the specimen requirements. |
| CPT Code(s): | |
| 87184 |