ARUP's Laboratory Test Directory

0054444: Varicella-Zoster Virus Antibody, IgG by ELISA (CSF)

Test Mnemonic: VZECSF
Methodology: Enzyme-Linked Immunosorbent Assay

Performed: Sun, Tue-Sat

Reported: Within 24 hours

Specimen Required:  
Collect: CSF.

Transport: 0.5 mL CSF at 2-8°C. (Min: 0.3 mL)  Submit specimen in an ARUP Standard Transport Tube.

Remarks: CSF is the only acceptable specimen type.

Unacceptable Conditions: Heat-inactivated or contaminated specimens.

Stability: Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval:
0.89 IV or less: Negative - No significant level of IgG antibody to varicella-zoster virus detected.
0.90-1.09 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 IV or greater: Positive - IgG antibody to varicella-zoster virus detected, which may indicate a current or past infection.

Interpretive Data:
The detection of antibodies to varicella-zoster in CSF may indicate central nervous system infection.  However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.

Please refer to Statement E in the Compliance Statements section in the front of the Laboratory Test Directory.



CPT Code(s):
86787

 

 

 
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