ARUP's Laboratory Test Directory
| 0051285: Myelin Associated Glycoprotein (MAG) Antibody, IgM |
| Test Mnemonic: MAGM ELISA | |
|
Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Wed Reported: 1-8 days |
| Specimen Required: | |
|
Collect: One 4 mL SST.
Transport: 1 mL serum at 2-8°C. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.15 mL serum at 2-8°C. Remarks: Separate serum from cells ASAP. Unacceptable Conditions: Heat inactivated, hemolyzed, severely lipemic, or contaminated specimens. Urine. Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year |
|
| Reference Interval: |
| Less than 1000 TU |
| Interpretive Data: | |
|
Detection of IgM autoantibody against myelin associated glycoprotein (MAG) suggests active demyelination in peripheral neuropathy. The possiblity of MAG antibody involvement in a suspected neuropathy may essentially be ruled out if a MAG IgM negative result is obtained. Detection of MAG IgM antibody by ELISA using human MAG (100 kD) antigen is significantly more sensitive and specific than MAG Western blot and IFA assays using primate antigen. TU=Titer Units Please refer to Statement D in the Compliance Statements section in the front of the Laboratory Test Directory. |
| CPT Code(s): | |
| 83516 |