ARUP's Laboratory Test Directory

0051152: Herpes Simplex Type 1 & Type 2 Glycoprotein G-Specific Antibodies, IgG by ELISA (HerpeSelect®)

Test Mnemonic: HERP PAN 2
Methodology: Enzyme-Linked Immunosorbent Assay

Performed: Sun-Sat

Reported: 1-2 days

Specimen Required:  
Collect: One 4 mL SST.

Transport: 1 mL serum at 2-8°C. (Min: 0.2 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 0.2 mL serum at 2-8°C.

Remarks: Separate serum or plasma from cells ASAP.  Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimen.  Please mark specimen plainly as "acute" or "convalescent."

Unacceptable Conditions: Contaminated, lipemic, hemolyzed, or heat-inactivated specimens.

Stability: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval:
 
Test Number Components Reference Interval
0050292Herpes Simplex Virus Type 1 Glycoprotein G-Specific Antibody, IgG by ELISA (HerpeSelect®) 0.89 IV or less: Negative - No significant level of detectable IgG antibody to HSV type 1 glycoprotein G.
0.90-1.10 IV: Equivocal - Questionable presence of IgG antibody to HSV type 1.  Repeat testing in 10-14 days may be helpful.
1.11 IV or greater: Positive - IgG antibody to HSV type 1 glycoprotein G detected, which may indicate a current or past HSV infection.
0050294Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by ELISA (HerpeSelect®) 0.89 IV or less: Negative - No significant level of detectable IgG antibody to HSV type 2 glycoprotein G.
0.90-1.10 IV: Equivocal - Questionable presence of IgG antibody to HSV type 2.  Repeat testing in 10-14 days may be helpful.
1.11 IV or greater: Positive - IgG antibody to HSV type 2 glycoprotein G detected, which may indicate a current or past HSV infection.

Interpretive Data:
Individuals infected with HSV may not exhibit detectable IgG antibody to glycoprotein G in the early stages of infection, and 5-10% of infections may occur with glycoprotein G deficient virus.  Detection of antibody presence in these cases may only be possible using a non-type specific screening test.



CPT Code(s):
86695 HSV 1; 86696 HSV 2

 

 

 
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