ARUP's Laboratory Test Directory

Humoral Immunity Panel II : 0050981

Mnemonic: HUMPAN II

Methodology: Multi-Analyte Fluorescent Detection
Performed: Mon-Sat
Reported: 1-3 days
Specimen Required: Collect:  One 4 mL serum separator tube.

Transport:  Two 1 mL aliquots of serum at 2-8°C. (Min: 0.5 mL per aliquot)  Submit specimens in two ARUP Standard Transport Tubes.

Pediatric Collection/Transport:  1 mL serum at 2-8°C.

Remarks:  Separate serum from cells ASAP. "Pre" and "post" diphtheria/tetanus and pneumococcal vaccine specimens should be submitted together for testing. "Post" specimen should be drawn 30 days after immunization and, if shipped separately, must be received within 60 days of "pre" specimen. PLEASE CLEARLY MARK SPECIMENS "PRE-VACCINE" OR "POST-VACCINE" SO THAT SPECIMENS WILL BE SAVED AND TESTED SIMULTANEOUSLY.

Unacceptable Conditions:  Plasma.

Stability:  After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles).
Reference Interval:
 
Test Number Components Reference Interval
0050210Diphtheria Antibody, IgG Antibody concentration of  > 0.1 IU/mL is usually considered protective.
0050535Tetanus Antibody, IgG Antibody concentration of > 0.1 IU/mL is usually considered protective.
0050725Streptococcus pneumoniae Antibodies, IgG (14 serotypes) Includes Serotypes 1, 3, 4*, 5, 6B*, 7F, 8, 9N, 9V*, 12F, 14*, 18C*, 19F*, 23F*

All serotypes tested are present in the 23-valent pure polysaccharide pneumococcal vaccine.  The serotypes marked with an asterisk are contained in the conjugated pneumococcal vaccine.

This assay is designed to use both "pre" and "post" samples to assess immune responsiveness to vaccination.  This test is not designed to determine protection to Streptococcus pneumoniae based on a single sample. 
 

CPT Code(s): 86317 Diphtheria; 86317 x14 Pneumo serotypes; 86317 Tetanus
 
 

 

 

 
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