ARUP's Laboratory Test Directory

0050980: Humoral Immunity Panel I

Test Mnemonic: HUMPAN I
Methodology: Nephelometry/Multi-Analyte Fluorescent Detection

Performed: Mon-Sat

Reported: 1-3 days

Specimen Required:  
Collect: Two 4 mL SST or one 10 mL SST.

Transport: Four 1 mL aliquots of serum at 2-8°C. (Min: 0.7 mL per aliquot)  Submit specimens in four ARUP Standard Transport Tubes.

Pediatric Collection/Transport: 0.75 mL aliquot of serum at 2-8°C.

Remarks: Separate serum from cells ASAP. "Pre" and "post" diphtheria/tetanus and pneumococcal vaccine specimens should be submitted together for testing. "Post" specimen should be drawn 30 days after immunization and, if shipped separately, must be received within 60 days of "pre" specimen. PLEASE CLEARLY MARK SPECIMENSS "PRE-VACCINE" OR "POST-VACCINE" SO THAT SPECIMENS WILL BE SAVED AND TESTED SIMULTANEOUSLY.

Unacceptable Conditions: Plasma.

Stability: After separation from cells: Ambient: 2 hours; Refrigerated: 8 days; Frozen: 1 year (avoid repeated freeze/thaw cycles). (Refer to individual components for further information.)

Reference Interval:

                                                                           


                                                                   
                                                                           
 
Test Number Components Reference Interval
0050210Diphtheria Antibody, IgG Antibody concentration of  > 0.1 IU/mL is usually considered protective.
0050535Tetanus Antibody, IgG Antibody concentration of > 0.1 IU/mL is usually considered protective.
0050725Streptococcus pneumoniae Antibodies, IgG (14 serotypes) Includes Serotypes 1, 3, 4*, 5, 6B*, 7F, 8, 9N, 9V*, 12F, 14*, 18C*, 19F*, 23F*

All serotypes tested are present in the 23-valent pure polysaccharide pneumococcal vaccine.  The serotypes marked with an asterisk are contained in the conjugated pneumococcal vaccine.

This assay is designed to use both "pre" and "post" samples to assess immune responsiveness to vaccination.  This test is not designed to determine protection to Streptococcus pneumoniae based on a single sample. 
0050340Immunoglobulin A, Serum  
 
0-30 days: 1-7 mg/dL
1 month: 1-53 mg/dL
2 months: 3-47 mg/dL
3 months: 5-46 mg/dL
4 months: 4-72 mg/dL
5 months: 8-83 mg/dL
6 months: 8-67 mg/dL
7-8 months: 11-89 mg/dL 		9-11 months: 16-83 mg/dL
1 year: 14-105 mg/dL
2 years: 14-122 mg/dL
3 years: 22-157 mg/dL
4 years: 25-152 mg/dL
5-7 years: 33-200 mg/dL
8-9 years: 45-234 mg/dL
10 years and older: 68-378 mg/dL
0050350Immunoglobulin G, Serum  
 
0- 30 days: 611-1542 mg/dL             
1 month: 241-870 mg/dL                         
2 months: 198-577 mg/dL           
3 months: 169-558 mg/dL                   
4 months: 188-536 mg/dL                         
5 months: 165-781 mg/dL                         
6 months: 206-676 mg/dL                           
7-8 months: 208-868 mg/dL                        		9-11 months: 282-1026 mg/dL
1 year: 331-1164 mg/dL
2 years: 407-1009 mg/dL
3 years: 423-1090 mg/dL
4 years: 444-1187 mg/dL
5-7 years: 608-1229 mg/dL
8-9 years: 584-1509 mg/dL
10 years and older: 768-1632 mg/dL
0050355Immunoglobulin M, Serum  
 
0-30 days: 0-24 mg/dL                     
1 month: 19-83 mg/dL                               
2 months: 16-100 mg/dL                         
3 months: 23-85 mg/dL                               
4 months: 26-96 mg/dL                             
5 months: 31-103 mg/dL                           
6 months: 33-97 mg/dL                               
7-8 months: 32-120 mg/dL                          		9-11 months: 39-142 mg/dL
1 year: 41-164 mg/dL
2 years: 46-160 mg/dL
3 years: 45-190 mg/dL
4 years: 41-186 mg/dL
5-7 years: 46-197 mg/dL
8-9 years: 49-230 mg/dL
10 years and older: 60-263 mg/dL
0050571Immunoglobulin G Subclass 1 Cord blood: 435-1084 mg/dL                5-6 years: 330-1065 mg/dL
0-2 months: 218-498 mg/dL                  7-8 years: 225-1100 mg/dL
3-5 months: 143-394 mg/dL                  9-10 years: 390-1235 mg/dL
6-8 months: 190-388 mg/dL                  11-12 years: 380-1420 mg/dL
9-23 months: 288-880 mg/dL                13-14 years: 165-1440 mg/dL
2 years: 170-950 mg/dL                          15 years and older: 240-1118 mg/dL
3-4 years: 290-1065 mg/dL
0050572Immunoglobulin G Subclass 2 Cord blood: 143-453 mg/dL                  5-6 years: 57-345 mg/dL
0-2 months: 40-167 mg/dL                    7-8 years: 42-375 mg/dL
3-5 months: 23-147 mg/dL                    9-10 years: 61-430 mg/dL
6-8 months: 37-60 mg/dL                      11-12 years: 73-455 mg/dL
9-23 months: 30-327 mg/dL                  13-14 years: 71-460 mg/dL
2 years: 22-440 mg/dL                            15 years and older: 124-549 mg/dL
3-4 years: 28-315 mg/dL
0050573Immunoglobulin G Subclass 3 Cord blood: 27-146 mg/dL                    5-6 years: 8-126 mg/dL
0-2 months: 4-23 mg/dL                        7-8 years: 9-107 mg/dL
3-5 months: 4-70 mg/dL                        9-10 years: 10-98 mg/dL
6-8 months: 12-62 mg/dL                      11-12 years: 16-194 mg/dL
9-23 months: 13-82 mg/dL                    13-14 years: 12-178 mg/dL
2 years: 4-69 mg/dL                                15 years and older: 21-134 mg/dL
3-4 years: 4-71 mg/dL
0050576Immunoglobulin G Subclass 4 Cord blood: 1-47 mg/dL                        5-6 years: 2-116 mg/dL
0-2 months: 1-33 mg/dL                        7-8 years: 0-138 mg/dL
3-5 months: 1-14 mg/dL                        9-10 years: 1-95 mg/dL
6-8 months: 1-16 mg/dL                        11-12 years: 1-153 mg/dL
9-23 months: 1-65 mg/dL                      13-14 years: 2-143 mg/dL
2 years: 0-120 mg/dL                              15 years and older: 7-89 mg/dL
3-4 years: 0-90 mg/dL

CPT Code(s):
86317 Diphtheria; 86317 x14 Pneumo serotypes; 86317 Tetanus; 82787 x4 IgG subclasses; 82784 Immunoglobulin IgA; 82784 Immunoglobulin IgG; 82784 Immunoglobulin IgM

 

 

 
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