ARUP's Laboratory Test Directory

Histone Antibody, IgG : 0050860

Mnemonic: AHA

Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Mon, Wed, Fri
Reported: 1-4 days
Specimen Required: Collect:  One 4 mL serum separator tube.

Storage/Transport Temperature:  1 mL serum at 2-8°C. (Min: 0.3 mL)  Submit specimen in an ARUP Standard Transport Tube.

Remarks:  Separate serum from cells ASAP.

Unacceptable Conditions:  Plasma.  Severely lipemic, bacterially contaminated, or hemolyzed specimens.

Stability (collection to initiation of testing):  After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
None detected: < 1.0 Units
Inconclusive: 1.0-1.5 Units
Positive: 1.6-2.5 Units
Strong positive: > 2.5 Units
Note: Histone antibodies are present in 20-55% of idiopathic systemic lupus erythematosus (SLE) and 80-95% of drug-induced SLE. They occur in less than 20% of other types of connective tissue diseases.
CPT Code(s): 83516
Cross References: Anti-Histone Antibody, IgG, Drug Induced SLE, Histone Antibody, IgG
 
 

 

 

 
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