ARUP's Laboratory Test Directory
| 0050860: Histone Antibody, IgG |
| Test Mnemonic: AHA | |
|
Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Mon, Wed, Fri Reported: 1-4 days |
| Specimen Required: | |
|
Collect: One 4 mL SST.
Transport: 1 mL serum at 2-8°C. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.15 mL serum at 2-8°C. Remarks: Separate serum from cells ASAP. Unacceptable Conditions: Plasma. Severely lipemic, bacterially contaminated, or hemolyzed specimens. Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) |
|
| Reference Interval: |
|
None detected: < 1.0 Units Inconclusive: 1.0-1.5 Units Positive: 1.6-2.5 Units Strong positive: > 2.5 Units |
| Note: | |
| Histone antibodies are present in 20-55% of idiopathic systemic lupus erythematosus (SLE) and 80-95% of drug-induced SLE. They occur in less than 20% of other types of connective tissue diseases. |
| CPT Code(s): | |
| 83516 |