ARUP's Laboratory Test Directory

0050860: Histone Antibody, IgG

Test Mnemonic: AHA
Methodology: Enzyme-Linked Immunosorbent Assay

Performed: Mon, Wed, Fri

Reported: 1-4 days

Specimen Required:  
Collect: One 4 mL SST.

Transport: 1 mL serum at 2-8°C. (Min: 0.5 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 0.15 mL serum at 2-8°C.

Remarks: Separate serum from cells ASAP.

Unacceptable Conditions: Plasma.  Severely lipemic, bacterially contaminated, or hemolyzed specimens.

Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval:
None detected: < 1.0 Units
Inconclusive: 1.0-1.5 Units
Positive: 1.6-2.5 Units
Strong positive: > 2.5 Units

Note:
Histone antibodies are present in 20-55% of idiopathic systemic lupus erythematosus (SLE) and 80-95% of drug-induced SLE. They occur in less than 20% of other types of connective tissue diseases.

CPT Code(s):
83516

 

 

 
All ARUP Sites:        www.aruplab.com     ·     www.arupconsult.com     ·     www.arup.utah.edu     ·     www.childx.org     ·     www.utahblood.org