ARUP's Laboratory Test Directory

Immunoglobulin G, CSF Index : 0050676

Mnemonic: IGG SYN

Ordering Recommendation: Preferred test is Oligoclonal Band Profile (0080440). Index test aids in the workup of suspected multiple sclerosis.
Methodology: Quantitative Nephelometry
Performed: Sun-Sat
Reported: Within 24 hours
Specimen Required: Collect: CSF AND serum separator tube.

Specimen Preparation: Centrifuge and separate CSF to remove cellular material. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL CSF AND 1 mL serum to individual ARUP Standard Transport Tubes. (Min: 0.4 mL CSF AND 0.4 mL serum)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Grossly bloody or hemolyzed specimens.

Stability (collection to initiation of testing): Ambient: 8 hours; Refrigerated: 8 days; Frozen: 1 year (if frozen within 24 hours)
Reference Interval:
IgG, Serum: 768-1632 mg/dL
IgG, CSF: 0.0-6.0 mg/dL
Albumin, Serum: 3500-5200 mg/dL
Albumin, CSF: 0-35 mg/dL
Albumin Index: 0.0-9.0
CSF IgG Synthesis Rate: ≤8.0 mg/d
IgG Albumin Ratio: 0.09-0.25
IgG Index: 0.28-0.66
CPT Code(s): 82784 x2; 82040; 82042
Cross References: IgG, CSF Index (Immunoglobulin G, CSF Index), Immunoglobulin G Index (Immunoglobulin G, CSF Index), Immunoglobulin G Synthesis Rate (Immunoglobulin G, CSF Index)