Reference Interval:
0.89 IV or less: Negative - No clinically significant level of Toxoplasma gondii IgM antibody detected.
0.90-1.09 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 IV or greater: Positive - Significant level of Toxoplasma gondii IgM antibody detected and may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
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| Interpretive Data: |
This test is performed using the Siemens Immulite 2000 chemiluminescent immunoassay. As suggested by the CDC, any equivocal or positive result should be retested using a different assay from another reference laboratory specializing in toxoplasmosis testing, such as Palo Alto Medical Foundation (Remington). The IgG Dye test, IgM ELISA, and reflex to Avidity and/or other tests as indicated should be ordered. In addition, a convalescent sample should be drawn for comparison. Caution should be exercised in the use of IgM antibody levels in prenatal screening. Any positive results in pregnant patients, that are confirmed positive by a second reference laboratory, should be evaluated by amniocentesis and PCR testing for Toxoplasma gondii.
For male and non-pregnant female patients with equivocal or positive results, PCR may also be useful if a specimen can be collected from an affected body site.
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| CPT Code(s): |
86778
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