ARUP's Laboratory Test Directory
| 0050228: West Nile Virus Antibodies, IgG & IgM by ELISA, CSF |
| Test Mnemonic: WNILE CSF | |
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Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Tue, Fri Reported: 1-8 days |
| Specimen Required: | |
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Collect: CSF.
Transport: 2 mL CSF at 2-8°C. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.3 mL CSF at 2-8°C. Unacceptable Conditions: Heat-inactivated, contaminated, or hemolyzed specimens. Stability: Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) |
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| Interpretive Data: | |
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This test is intended to be used as a semi-quantitative means of detecting West Nile virus-specific IgG and IgM in CSF samples in which there is a clinical suspicion of West Nile virus infection. This test should not be used solely for quantitative purposes, nor should the results be used without correlation to clinical history or other data. Because other members of the Flaviviridae family, such as St. Louis encephalitis virus, show extensive cross-reactivity with West Nile virus, serologic testing specific for these species should also be performed. The detection of antibodies to West Nile virus in cerebrospinal fluid may indicate central nervous system infection. However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier. |
| CPT Code(s): | |
| 86789 WNV IgG, 86788 WNV IgM |