ARUP's Laboratory Test Directory

Cryoglobulin, Qualitative : 0050185

Mnemonic: CRYGB

Methodology: Qualitative Cold Precipitation
Performed: Sun-Sat
Reported: 3-5 days
Specimen Required: Patient Prep: Fasting specimen preferred.

Collect: Whole blood drawn in a pre-warmed (37°C) syringe. Specimen may be drawn directly into a pre-warmed plain red.

Specimen Preparation: Maintain whole blood at 37°C until clotting is complete; do not refrigerate or freeze at any time. Immediately after blood has been obtained, transfer specimen to a pre-warmed plain red (if not used for collection). Separate plasma from cells using a 37°C centrifuge, if possible. Transfer 3 mL serum to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature: Room temperature.

Remarks: Proper collection and transport of specimen is critical to the outcome of the assay. Quantities less than 3 mL may affect the sensitivity of the assay.

Unacceptable Conditions: Refrigerated or frozen specimens. Separator tubes. Grossly hemolyzed or lipemic specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 1 week; Refrigerated: Unacceptable; Frozen: Unacceptable
Reference Interval:
Negative at 72 hours.
Note: The specimen is examined daily for the presence or absence of cryoglobulins over a period of three days. Cryoglobulins are usually associated with certain plasma cell and lymphoproliferative disorders, but have also been demonstrated in collagen vascular diseases, hepatitis C infection and infections such as infectious mononucleosis and cytomegalovirus disease. They may also be found in low levels in apparently healthy individuals.
CPT Code(s): 82595
 
 

 

 

 
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