ARUP's Laboratory Test Directory

C-Reactive Protein, High Sensitivity : 0050182

Mnemonic: HSCRP

Methodology: Immunoturbidimetric
Performed: Sun-Sat
Reported: Within 24 hours
Specimen Required: Collect:  One 4 mL serum separator tube.  Also acceptable: plasma separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Storage/Transport Temperature:  1 mL serum at 2-8°C. (Min: 0.3 mL)  Submit specimen in an ARUP Standard Transport Tube.

Remarks:  Allow specimen to clot completely at room temperature.  Separate serum or plasma from cells ASAP.

Unacceptable Conditions:  Hemolyzed specimens.

Stability (collection to initiation of testing):  After separation from cells: Ambient: 2 days; Refrigerated: 2 months; Frozen: 1 year
Reference Interval:
≤ 3.0 mg/L
Interpretive Data: Patients with higher hs-CRP concentrations are more likely to develop stroke, myocardial infarction, and severe peripheral vascular disease. 

CRP is a nonspecific marker of inflammation and a variety of conditions other than atherosclerosis may cause elevated concentrations. If the first result is greater than 3.0 mg/L, recommend repeating test at least 2 weeks later in a metabolically stable state, free of infection or acute illness.  The lower of the two results should be used to determine the patient's risk.
 
hs-CRP results are used to assign risk as follows (Clin Chem 2009; 55:378-84):  
Less than 1.0 mg/L
1.0-3.0 mg/L
3.1-9.9 mg/L
Greater than 9.9 mg/L
Low risk
Average risk
High risk
Very high risk

CPT Code(s): 86141
Cross References: CRP High Sensitivity, High Sensitivity, CRP, HSCRP
 
 

 

 

 
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