ARUP's Laboratory Test Directory

C-Reactive Protein, High Sensitivity : 0050182

Mnemonic: HSCRP

Methodology: Quantitative Immunoturbidimetric
Performed: Sun-Sat
Reported: Within 24 hours
Specimen Required: Collect: Serum separator tube. Also acceptable: Plasma separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Specimen Preparation: Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Hemolyzed specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 months; Frozen: 1 year
Reference Interval:
3.0 mg/L or less
Interpretive Data: Patients with higher hs-CRP concentrations are more likely to develop stroke, myocardial infarction, and severe peripheral vascular disease. 

CRP is a nonspecific marker of inflammation and a variety of conditions other than atherosclerosis may cause elevated concentrations. If the first result is greater than 3.0 mg/L, recommend repeating test at least 2 weeks later in a metabolically stable state, free of infection or acute illness.  The lower of the two results should be used to determine the patient's risk.
 
hs-CRP results are used to assign risk as follows (Clin Chem 2009; 55:378-84):  
Less than 1.0 mg/L
1.0-3.0 mg/L
3.1-9.9 mg/L
Greater than 9.9 mg/L
Low risk
Average risk
High risk
Very high risk

CPT Code(s): 86141
Cross References: CRP High Sensitivity (C-Reactive Protein, High Sensitivity), High Sensitivity, CRP (C-Reactive Protein, High Sensitivity), HSCRP (C-Reactive Protein, High Sensitivity)
 
 

 

 

 
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