ARUP's Laboratory Test Directory
| 0050070: Entamoeba histolytica (amebiasis), Antibody, IgG |
| Test Mnemonic: AMB | |
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Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Tue, Fri Reported: 1-5 days |
| Specimen Required: | |
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Collect: One 4 mL SST.
Transport: 1 mL serum at 2-8°C. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.15 mL serum at 2-8°C. Remarks: Separate serum from cells ASAP. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent." Unacceptable Conditions: Severely lipemic, contaminated, heat-inactivated, or hemolyzed specimens. Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) |
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| Reference Interval: |
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0.79 IV or less: Negative - No significant level of detectable E. histolytica IgG antibody. 0.80-1.19 IV: Equivocal - Repeat testing in 10-14 days may be helpful. 1.20 IV or greater: Positive - IgG antibody to E. histolytica detected, suggestive of a current or past infection. |
| Interpretive Data: | |
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Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change on two appropriately timed specimens where both tests are done in the same laboratory at the same time.
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| Note: | |
| In the case of extraintestinal complications, a positive antibody can indicate amebiasis even though stool findings are negative. |
| CPT Code(s): | |
| 86753 |