Estrogen/Progesterone Receptor Assay, Paraffin : ARUP Lab Tests

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0049210: Estrogen/Progesterone Receptor Assay, Paraffin

Anatomic Pathology Test Request Form Recommended

Test Mnemonic: ERPR IP
Methodology: Immunohistochemistry Performed: Mon-Fri Reported: Within 5 days

Specimen Required:

Collect: Tumor tissue.

Transport: Paraffin-embedded, formalin-fixed tissue block enriched with tumor at 20-25°C. Protect paraffin block from excessive heat. Ship in cooled container during summer months. Include surgical pathology report.

Unacceptable Conditions: Paraffin block with no tumor tissue remaining; samples fixed in formalin substitute.

Stability: Ambient: Indefinitely; Refrigerated: Acceptable; Frozen: Unacceptable

Reference Interval:

ERA:	PGRA:
Negative: < 5% of nuclei staining Borderline: 5-19% of nuclei staining Positive: ³ 20% of nuclei staining	Negative: < 5% of nuclei staining Borderline: 5-19% of nuclei staining Positive: ³ 20% of nuclei staining

Interpretive Data:
Assay is performed on Paraffin-embedded, formalin-fixed tissue. Antibody clone for ER is SP1, clone for PR is 1E2 and the detection system is LSAB.

CPT Code(s):
88360 ER; 88360 PR

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