Estrogen/Progesterone Receptor Assay, Paraffin : ARUP Lab Tests

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Estrogen/Progesterone Receptor Assay, Paraffin : 0049210

Anatomic Pathology Test Request Form Recommended

Mnemonic: ERPR IP

Methodology:	Immunohistochemistry
Performed:	Mon-Fri
Reported:	Within 5 days
Specimen Required:	Collect: Tumor tissue. Storage/Transport Temperature: Paraffin-embedded, formalin-fixed tissue block enriched with tumor at 20-25°C. Protect paraffin block from excessive heat. Ship in cooled container during summer months. Include surgical pathology report. Unacceptable Conditions: Paraffin block with no tumor tissue remaining; specimens fixed in formalin substitute. Stability (collection to initiation of testing): Ambient: Indefinitely; Refrigerated: Acceptable; Frozen: Unacceptable

Reference Interval:

ERA:	PGRA:
Negative: < 5% of nuclei staining Borderline: 5-19% of nuclei staining Positive: ≥ 20% of nuclei staining	Negative: < 5% of nuclei staining Borderline: 5-19% of nuclei staining Positive: ≥ 20% of nuclei staining

Interpretive Data:

Assay is performed on Paraffin-embedded, formalin-fixed tissue. Antibody clone for ER is SP1, clone for PR is 1E2 and the detection system is LSAB.

CPT Code(s):

88360 ER; 88360 PR

Cross References:

ERA & PRA (Paraffin), Steroid Receptor Assay (Paraffin)

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