ARUP's Laboratory Test Directory

Protein C and S Panel, Functional : 0030182

Mnemonic: C/S PANEL

Ordering Recommendation: Acceptable panel to detect protein C and S deficiencies. Preferred test for detecting protein S deficiency is Protein S Free, Antigen (0098894). Do not order if the individual has been on warfarin therapy in the previous 2-4 weeks.
Methodology: Clotting
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Collect: Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation: Transfer 2 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature: CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Remarks: Include list of medications.

Unacceptable Conditions: Serum. Non-frozen or hemolyzed specimens.

Stability (collection to initiation of testing): Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months, at -70°C: 6 months
Reference Interval:
80-203%
 
Test Number Components Reference Interval
0030113Protein C, Functional 1-4 days: 17-53%
5-29 days: 20-64%
30-89 days: 21-65%
90-179 days: 28-80%
180-364 days: 37-81%
1-6 years: 40-92%
7-9 years: 56-144%
10-11 years: 59-143%
12-13 years: 57-142%
14-15 years: 56-162%
16-17 years: 68-154%
18 years and older: 77-173%
0030114Protein S, Functional Male
1-89 days: 15-55%
90-179 days: 35-92%
180-364 days: 45-115%
1-5 years: 62-120%
6 years:  62-130%
7-9 years: 66-140%
10-11 years: 65-139%
12-13 years: 72-139%
14-15 years: 68-145%
16-17 years: 77-167%
18 years and older: 66-143%

Female
1-89 days: 15-55%
90-179 days: 35-92%
180-364 days: 45-115%
1-5 years: 62-120%
6 years:  62-130%
7-9 years: 62-151%
10-11 years: 65-142%
12-13 years: 70-140%
14-15 years: 55-145%
16-17 years: 51-147%
18 years and older: 57-131%
 
Interpretive Data: Refer to report.
CPT Code(s): 85303; 85306
Cross References: Protein C and S Activity (Protein C & S Panel, Functional)