ARUP's Laboratory Test Directory

Protein C & S Panel, Functional : 0030182

Mnemonic: C/S PANEL

Methodology: Clotting
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Collect:  Two 5 mL (lt. blue sodium citrate).  (Min: two 3 mL) Refer to the Hemostasis/Thrombosis Specimens section in the front of this User's Guide for specimen collection instructions.

Transport:  4 mL platelet-poor plasma, frozen.  (Min: 1.5 mL) Submit specimen in an ARUP Standard Transport Tube.

Remarks:  CRITICAL FROZEN.  Separate specimens must be submitted when multiple tests are ordered. List medications.

Unacceptable Conditions:  Serum.  Nonfrozen or hemolyzed specimens.

Stability:  Ambient: 2 hours; Refrigerated: 4 hours; Frozen: 2 weeks
Reference Interval:
80-203%
 
Test Number Components Reference Interval
0030113Protein C, Functional 1-4 days: 17-53%
5-29 days: 20-64%
30-89 days: 21-65%
90-179 days: 28-80%
180-364 days: 37-81%
1-6 years: 40-92%
7-9 years: 56-144%
10-11 years: 59-143%
12-13 years: 57-142%
14-15 years: 56-162%
16-17 years: 68-154%
18 years and older: 77-173%
0030114Protein S, Functional Male
1-89 days: 15-55%
90-179 days: 35-92%
180-364 days: 45-115%
1-5 years: 62-120%
6 years:  62-130%
7-9 years: 66-140%
10-11 years: 65-139%
12-13 years: 72-139%
14-15 years: 68-145%
16-17 years: 77-167%
18 years and older: 66-143%

Female

1-89 days: 15-55%
90-179 days: 35-92%
180-364 days: 45-115%
1-5 years: 62-120%
6 years:  62-130%
7-9 years: 62-151%
10-11 years: 65-142%
12-13 years: 70-140%
14-15 years: 55-145%
16-17 years: 51-147%
18 years and older: 57-131%
 

Interpretive Data: Patients on oral anticoagulants will have decreased functional protein C/S values. Patients should be off oral anticoagulant therapy for two weeks for accurate measurement of functional protein C/S levels.

Interfering Factors: Artifactually decreased functional protein C/S values may be seen in patients with abnormally elevated levels of factor VIII. Artifactually increased functional protein C/S values may be seen in patients on heparin therapy.
CPT Code(s): 85303 Protein C functional; 85306 Protein S functional
 
 

 

 

 
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