ARUP's Laboratory Test Directory

Thrombotic Risk, Inherited Etiologies (Most Common) with Reflex to Factor V Leiden : 0030133

Mnemonic: THROM COM

Methodology: Refer to individual components
Performed: Refer to individual components
Reported: 2-7 days
Specimen Required: Patient Prep: Fasting specimen preferred for homcysteine (green, sodium or lithium heparin).

Collect: Lt. blue (sodium citrate) AND lavender (EDTA) or pink (K2EDTA) AND green (sodium or lithium heparin).

Specimen Preparation: Transport two 2 mL aliquots platelet-poor plasma (sodium citrate) (Min: 1 mL/aliquot) AND 1 mL plasma (sodium or lithium heparin) (Min: 0.4 mL) AND 5 mL whole blood (EDTA).

Storage/Transport Temperature: Platelet-poor Plasma: CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Plasma: Frozen.
Whole Blood: Refrigerated.


Unacceptable Conditions: Refer to individual components.

Stability (collection to initiation of testing): Refer to individual components.
Reference Interval:
 
Test Number Components Reference Interval
0030235Partial Thromboplastin Time 24-35 seconds
0030095Factor VIII, Activity 0-6 years: 56-191%
7-9 years: 76-199%
10-11 years: 80-209%
12-13 years: 72-198%
14-15 years: 69-237%
16-17 years: 63-221%
18 years and older: 56-191%
0099869Homocysteine, Total < 11 µmol/L, for both male and female
0056060Prothrombin (F2) G20210A Mutation Negative: This sample is negative for the factor II, prothrombin 20210A mutation.
 APC Resistance Profile Greater than 0.61
 Factor V Leiden by PCR & Fluorescence Monitoring Negative: The sample is negative for factor V Leiden, R506Q mutation.
 

Note: If APC resistance is normal, then no further testing will be added. If APC resistance is abnormally low, then Factor V Leiden by PCR will be added. Additional charges apply.
CPT Code(s): 85730 PTT; 85240 F8; 83090 tHcy; 83891 Isolation; 83898 Amplification; 83896 Nucleic acid probes; 83912 Int/report; 85307 APC; if reflexed, add 83891 Isolation; 83898 Amplification; 83896 Nucleic acid probes; 83912 Int/report - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
Cross References: Hypercoag (Thrombotic Risk, Inherited Etiologies (Most Common) with Reflex to Factor V Leiden), Hypercoagulable Panel (Thrombotic Risk, Inherited Etiologies (Most Common) with Reflex to Factor V Leiden) , Thrombophilia (Thrombotic Risk, Inherited Etiologies (Most Common) with Reflex to Factor V Leiden)
 
 

 

 

 
All ARUP Sites:        www.aruplab.com     ·     www.arupconsult.com     ·     www.arup.utah.edu     ·     www.childx.org     ·     www.utahblood.org