ARUP's Laboratory Test Directory
| 0030133: Thrombotic Risk, Inherited Etiologies (Most Common) with Reflex to Factor V Leiden |
| Test Mnemonic: THROM COM | |
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Methodology: Refer to individual components
Performed: Refer to individual components Reported: 2-7 days |
| Specimen Required: | |
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Collect: One 5 mL lt. blue (sodium citrate) for factor VIII, PTT, AND one 5 mL lt. blue (sodium citrate) APC (Min: 5 mL), AND one 5 mL lavender (EDTA) prothrombin nucleotide, AND one 5 mL lavender (EDTA) for homocysteine (fasting sample is preferred for homocysteine).
Transport: Two 2 mL aliquots platelet-poor plasma (lt. blue, sodium citrate), frozen for factor VIII, PTT, and APC (Min: 1 mL per aliquot) AND one 1 mL plasma (lavender, EDTA), frozen for homocysteine AND one 5 mL whole blood (lavender, EDTA) at 2-8°C for prothrombin nucleotide. (Min: 3 mL) Do not freeze whole blood. Pediatric Collection/Transport: Two 1 mL aliquots platelet-poor plasma (lt. blue, sodium citrate), frozen for factor VIII, PTT, and APC AND 0.4 mL plasma (lavender, EDTA), frozen for homocysteine AND one 1 mL whole blood (lavender, EDTA) at 2-8°C for prothrombin nucleotide. Do not freeze whole blood. Remarks: Factor VIII is a CRITICAL FROZEN. Unacceptable Conditions: Refer to individual components. Stability: Refer to individual components. |
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| Note: | |
| If APC resistance is normal, no further testing will be performed. If APC resistance is abnormally low, then Factor V Leiden by PCR will be added. Additional charges may apply. |
| CPT Code(s): | |
| 85730 PTT; 85240 F8; 83090 tHcy; 83890 Isolation; 83898 Amplification; 83896 Nucleic acid probes; 83912 Int/report; 85307 APC; if reflexed, add 83890 Isolation; 83898 Amplification; 83896 Nucleic acid probes; 83912 Int/report - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders. |