ARUP's Laboratory Test Directory

0030127: APC Resistance Profile

Test Mnemonic: APC RST
Methodology: Clotting

Performed: Mon, Wed, Fri

Reported: 1-4 days

Specimen Required:  
Collect: One 5 mL lt. blue (sodium citrate). (Min: 3 mL) Refer to the Hemostasis/Thrombosis Specimens section in the front of this User's Guide for specimen collection instructions.

Transport: 1.5 mL platelet-poor plasma, frozen. (Min: 1 mL) Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 1 mL platelet-poor plasma, frozen.

Unacceptable Conditions: Serum.  Nonfrozen or hemolyzed specimen.

Stability: Ambient: 4 hours; Refrigerated: 4 hours; Frozen: 2 weeks

Reference Interval:
Greater than 0.61

Interpretive Data:
Ratios less than or equal to 0.61 suggest APC resistance. This method uses factor V deficient plasma; therefore, APC resistance due to a nonfactor V mutation will not be detected.  Extreme factor V deficiency may cause abnormal ratio.



CPT Code(s):
85307

 

 

 
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