ARUP's Laboratory Test Directory

Protein C and S Panel, Total, Antigen : 0030116

Mnemonic: C/S TOTAL

Ordering Recommendation: Not recommended. Preferred tests for detection of protein C and S deficiencies are Protein C Functional (0030113) and Protein S Free Antigen (0098894). Do not order if individual has been on warfarin therapy in the previous 2-4 weeks.
Methodology: Microlatex Particle-Mediated Immunoassay
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Collect: Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation: Transfer 2 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature: CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions: Serum. Non-frozen or hemolyzed specimens.

Stability (collection to initiation of testing): Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months, at -70°C: 6 months
Reference Interval:
 
Test Number Components Reference Interval
0030111Protein C, Total Antigen 1-4 days: 17-53%
5-29 days: 20-64%
30-89 days: 21-65%
90-179 days: 28-80%
180-364 days: 37-81%
1-5 years: 40-92%
6-10 years: 45-93%
11 years and older: 63-153%
0030112Protein S, Total Antigen 1-4 days: 12-60%
5-29 days: 22-78%
30-89 days: 33-93%
90-179 days: 54-118%
180-364 days: 55-119%
1-5 years: 54-118%
6-10 years: 41-114%
11 years and older: Females: 63-126%; Males: 84-134%
 
Interpretive Data: Refer to report.
CPT Code(s): 85302; 85305