Alkaline Phosphatase Isoenzymes : ARUP Lab Tests

Testing Information

ARUP's Laboratory Test Directory

Alkaline Phosphatase Isoenzymes : 0021020

Mnemonic: ALKP-ISO

Methodology:	Heat Inactivation/Enzymatic
Performed:	Sun-Sat
Reported:	1-3 days
Specimen Required:	Collect: One 7 mL serum separator tube or one 7 mL green (sodium or lithium heparin).. Storage/Transport Temperature: 2 mL serum or plasma at 2-8°C. (Min: 1 mL) Submit specimen in an ARUP Standard Transport Tube. Remarks: Separate serum from cells ASAP and refrigerate or freeze. Fasting specimen is recommended. Unacceptable Conditions: Specimens collected in EDTA, sodium fluoride, or potassium oxalate. Grossly hemolyzed specimens. Stability (collection to initiation of testing): After separation from cells: Ambient: 1 hour; Refrigerated: 1 week (total activity will increase 2% per day); Frozen: 1 year

Reference Interval:

Test Number	Components
0020005	Alkaline Phosphatase, Serum or Plasma	Male 0-30 days: 60-320 U/L 1-11 months: 70-350 U/L 1-3 years: 125-320 U/L 4-6 years: 150-370 U/L 7-9 years: 150-440 U/L 10-11 years: 150-470 U/L 12-13 years: 160-500 U/L 14-15 years: 130-530 U/L 16-19 years: 60-270 U/L 20 years and older: 40-120 U/L	Female 0-30 days: 60-320 U/L 1-11 months: 70-350 U/L 1-3 years: 125-320 U/L 4-6 years: 150-370 U/L 7-9 years: 150-440 U/L 10-11 years: 150-530 U/L 12-13 years: 110-525 U/L 14-15 years: 55-305 U/L 16-19 years: 40-120 U/L 20 years and older: 40-120 U/L
	Bone	Male 1-6 years: 0-208 U/L 7-9 years: 0-264 U/L 10-15 years: 0-340 U/L 16-19 years: 0-165 U/L 20 years and older: 0-55 U/L	Female 1-6 years: 0-189 U/L 7-9 years: 0-246 U/L 10-13 years: 0-340 U/L 14-15 years: 0-91 U/L 16 years and older: 0-55 U/L
	Liver	Male 1-6 years: 0-145 U/L 7-11 years: 0-182 U/L 12-15 years: 0-226 U/L 16-19 years: 0-114 U/L 20 years and older: 0-94 U/L	Female 1-9 years: 0-148 U/L 10-15 years: 0-162 U/L 16 years and older: 0-94 U/L

Interpretive Data:

Bone Specific Alkaline Phosphatase (0070053) and 5'Nucleotidase (0080235) may be useful in identifying disorders of bone and liver, respectively.

Note:

Heat-stable isoenzymes, such as the one produced during pregnancy, will interfere with the interpretation of this assay.

CPT Code(s):

84075 ALKP total; 84080 ALKP isoenzymes

Cross References:

Alkaline Phosphatase, Fractionated , Isoenzymes, Alkaline Phosphatase