ARUP's Laboratory Test Directory

0021020: Alkaline Phosphatase Isoenzymes

Test Mnemonic: ALKP-ISO
Methodology: Heat Inactivation/Enzymatic

Performed: Sun-Sat

Reported: 1-3 days

Specimen Required:  
Collect: One 7 mL SST or one 7 mL green (sodium or lithium heparin).

Transport: 2 mL serum or plasma at 2-8°C.  (Min: 1 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 0.5 mL serum or plasma at 2-8°C.

Remarks: Separate serum from cells ASAP and refrigerate or freeze.  Fasting specimen is recommended.

Unacceptable Conditions: Specimens collected in EDTA, sodium fluoride, or potassium oxalate.  Grossly hemolyzed specimens.

Stability: After separation from cells: Ambient: 1 hour; Refrigerated: 1 week (total activity will increase 2% per day); Frozen: 1 year

Reference Interval:
 
Test Number Components   
0020005 Alkaline Phosphatase, Serum or Plasma Male
0-30 days: 60-320 U/L
1-11 months: 70-350 U/L
1-3 years: 125-320 U/L
4-6 years: 150-370 U/L
7-9 years: 150-440 U/L
10-11 years: 150-470 U/L
12-13 years: 160-500 U/L
14-15 years: 130-530 U/L
16-19 years: 60-270 U/L
20 years and older: 40-120 U/L 		Female
0-30 days: 60-320 U/L
1-11 months: 70-350 U/L
1-3 years: 125-320 U/L
4-6 years: 150-370 U/L
7-9 years: 150-440 U/L
10-11 years: 150-530 U/L
12-13 years: 110-525 U/L
14-15 years: 55-305 U/L
16-19 years: 40-120 U/L
20 years and older: 40-120 U/L
 Bone Male
1-6 years: 0-208 U/L
7-9 years: 0-264 U/L
10-15 years: 0-340 U/L
16-19 years: 0-165 U/L
20 years and older: 0-55 U/L 		Female
1-6 years: 0-189 U/L
7-9 years: 0-246 U/L
10-13 years: 0-340 U/L
14-15 years: 0-91 U/L
16 years and older: 0-55 U/L
 Liver Male
1-6 years: 0-145 U/L
7-11 years: 0-182 U/L
12-15 years: 0-226 U/L
16-19 years: 0-114 U/L
20 years and older: 0-94 U/L 		Female
1-9 years: 0-148 U/L
10-15 years: 0-162 U/L
16 years and older: 0-94 U/L

Interpretive Data:
Bone Specific Alkaline Phosphatase (0070053) and 5'Nucleotidase (0080235) may be useful in identifying disorders of bone and liver, respectively.



Note:
Heat-stable isoenzymes, such as the one produced during pregnancy, will interfere with the interpretation of this assay.

CPT Code(s):
84075 ALKP total; 84080 ALKP isoenzymes

 

 

 
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