Consultations are provided for hematopathology cases, including leukemia, lymphoma, metastatic neoplasms with bone marrow involvement, etc. Materials are reviewed by an ARUP pathologist who is board certified in hematopathology, and a consultative opinion is provided in a pathology report. Additional stains and ancillary testing may be ordered by the ARUP pathologist to provide a complete report. Consultations are not intended to provide a primary diagnosis for hematopathology cases.

Required Documentation

For all consultation requests, please include:

  1. A cover letter summarizing the following:
    1. Patient’s pertinent clinical and pathological history, diagnosis, and any specific questions to be addressed
    2. Contact information (name, phone, and fax) for the submitting clinical physician in case we need additional history
    3. Contact information for your laboratory (facility name, return address, phone, fax) so that materials can be returned to the correct location, and in case we need to request additional materials
  2. All preliminary pathology reports, as well as corresponding ancillary results (CBC, flow cytometry, cytogenetics, fluorescence in situ hybridization [FISH], and molecular/next generation sequencing [NGS])
  3. All stained slides for each specimen, including all bone marrow parts, levels, immunohistochemistry (IHC), special stains, and controls, as well as one corresponding block or 20 unstained slides to prevent any delays if additional testing is required
How To Electronically Order a Hematopathology Consultation
  1. Using ARUP ConnectTM or your lab information system (LIS) interface, order Consultation, Hematopathology (test code 2013258).
  2. Provide the required documentation listed above, including any pertinent reporting from the patient’s medical record not mentioned.
  3. Securely pack material in padded packaging using either ARUP’s Paraffin Tissue and Extracted Nucleic Acid Transport Kit (preferred) or plastic slide holders that are closed securely. If including a paraffin block, especially in warmer months, include an ice/gel pack to ensure that the block does not melt in transit.
  4. Send materials to the shipping address below using your ARUP courier.
How To Manually Order a Hematopathology Consultation
  1. Call 1-800-522-2787 and ask for requisition form #32960.
  2. Once obtained, fully complete the top portion of the form.
  3. On the requisition form, choose the consultation type 2013258 Consultation, Hematopathology. If the consultation type is not chosen, the case will be placed on Except. List the number of slides and blocks being submitted.
  4. Provide the required documentation listed above, including any pertinent reporting from the patient’s medical record not mentioned.
  5. If patient billing is requested, include patient demographic characteristics, including insurance information.
  6. Securely pack material in padded packaging using either ARUP’s Paraffin Tissue and Extracted Nucleic Acid Transport Kit (preferred) or plastic slide holders that are closed securely. If including a paraffin block, especially in warmer months, include an ice/gel pack to ensure that the block does not melt in transit.
  7. Send materials to the shipping address below using your mail carrier (FedEx is preferred). Select 1–2 day shipping. Please do not use USPS.

Note: If you are a patient and are requesting a consultation (second opinion) directly or need any additional assistance, please call our Hematopathology office at 801-584-5240.

Shipping

Send the required documentation and materials to:

ARUP Laboratories
Specimen Processing
500 Chipeta Way
Salt Lake City, UT 84108

Hemepath Office
Phone: 801-584-5240
Fax: 801-584-5124

Specimen Preparation

  • Refer to ARUP Consultation Collection Instructions for specimen requirements and use our preferred Paraffin Tissue and Extracted Nucleic Acid Transport Kit for packaging.
  • Unstained slides should be protected from excessive heat and from prolonged air-drying.
  • To contact the ARUP account executive in your area, please call Client Services at 1-800-522-2787.

Hematopathology Primary Diagnostic Services

ARUP offers comprehensive primary diagnostic workups for bone marrow biopsies guided by board-certified hematopathologists. This comprehensive bone marrow service integrates multiple test results to diagnose and classify hematologic malignancies.

Testing may include the following:

  • Primary testing: Morphology (including IHC and in situ hybridization), flow cytometry, and chromosome analysis
  • Secondary testing: Molecular assays such as FISH, microarray, sequencing, and polymerase chain reaction (PCR)-based assays, as medically necessary

NOTE: Primary diagnostic services require pathologist medical licensure in the state where the patient underwent the biopsy procedure; therefore, prior laboratory approval is required to utilize this service to ensure adequate coverage.

If you have further inquiries about ARUP’s ability to provide comprehensive bone marrow services, please fill out the Hematopathology Testing Interest Form.