Jessica F. Williams, MD, PhD

Assistant Professor (Clinical), University of Utah School of Medicine

Specialties

• Genitourinary pathology
• Solid tumor molecular pathology

Education

• Medical Degree—Yale School of Medicine
• Doctorate Degree—Yale School of Medicine
• Residency—Anatomic Pathology, Brigham and Women’s Hospital, Harvard Medical School
• Fellowship—Molecular Genetic Pathology, University of Utah School of Medicine
• Fellowship—Genitourinary Pathology, Brigham and Women’s Hospital, Harvard Medical School

Certifications/Affiliations

• American Board of Pathology (Anatomic Pathology; Molecular Genetic Pathology)
• College of American Pathologists
• United States and Canadian Academy of Pathology
• Association for Molecular Pathology

Research Interests

• Molecular and immunohistochemical signatures of neuroendocrine and neuroectodermal tumors of the genitourinary system
• Epigenetic mechanisms of nuclear stability and chromatin functionality

Recent Publications

• Gebrael G, Sayegh N, Hage, et al. Genomic biomarkers of survival in patients with metastatic hormone-sensitive prostate cancer undergoing intensified androgen deprivation therapy. Prostate Cancer Prostatic Dis. Published online Jan. 2025.
• Alchoueiry M, Mansour H, Khabibullin D, et al. Targeting KIT with antibody-drug conjugates in chromophobe renal cell carcinoma. Clin Genitourin Cancer. 2025;23(4):102359.
• Gandhi MM, Elkrief A, Moore CG, et al. Gene copy deletion of STK11, KEAP1, and SMARCA4: clinicopathologic features and association with the outcomes of immunotherapy with or without chemotherapy in nonsquamous NSCLC. J Thorac Oncol. 2025;20(6):725-738.
• Williams JF, Lucas FM, Carrasco RD, et al. Primary cutaneous EBV+ extranodal NK/T-cell lymphoma of gamma/delta T-cell lineage in the posttransplantation setting. J Cutan Pathol. 2024;51(10):777-782.
• Williams JF, Surovtsev IV, Schreiner SM, et al. The condensation of HP1α/Swi6 imparts nuclear stiffness. Cell Rep. 2024;43(7):114373.
• Yuan T, Yan H, Bailey MLP, et al. Effect of loops on the mean-square displacement of Rouse-model chromatin. Phys Rev E. 2024;109(4-1):044502.
• Bailey MLP, Surovtsev I, Williams JF, et al. Loops and the activity of loop extrusion factors constrain chromatin dynamics. Mol Biol Cell. 2023;34(8):ar78.
• Williams JF, Vivero M. Diagnostic criteria and evolving molecular characterisation of pulmonary neuroendocrine carcinomas. Histopathology. 2022;81(5):556-568.
• Williams JF, Zhao M, Najdawi F, et al. grading of medullary thyroid carcinoma: an interobserver reproducibility study. Endocr Pathol. 2022;33(3):371-377.
• Yan H, Surovtsev I, Williams JF, et al. Extrusion of chromatin loops by a composite loop extrusion factor. Phys Rev E. 2021;104(2-1):024414.
• Bailey MLP, Yan H, Surovtsev I, et al. Covariance distributions in single particle tracking. Phys Rev E. 2021;103(3-1):032405.