Eric Snyder, MD, PhD

Professor, University of Utah School of Medicine

Education

• Medical Degree—Washington University
• Doctorate Degree—Molecular/Cellular Biology, Washington University
• Residency—Anatomic Pathology, Brigham and Women’s Hospital
• Postdoctoral Research Fellowship—Massachusetts Institute of Technology

Certifications/Affiliations

• American Board of Pathology (Anatomic Pathology)

Research Interests

• Lineage plasticity
• Lung cancer
• Pancreatic cancer
• Mouse models of cancer

Awards

• Burroughs Wellcome Career Award for Medical Scientists, 2011
• Pathobiology Prize, United States and Canadian Academy of Pathology, 2009

Recent Publications

• Fang P, Wilson ER, Larsen SN, et al. Differential control of growth and identity by HNF4α isoforms in pancreatic ductal adenocarcinoma. Mol Cancer Res. Published online Jul 2025.
• OToole KT, Martinez A, Murphy B, et al. Characterization of the BRAF interactome identifies BRAF (V600E) TP53 interaction in melanoma (preprint). bioRxiv. 2025:2025.06.20.660711.
• Fort G, Arnold H, Camolotto SA, et al. Opposing lineage specifiers induce a protumor hybrid identity state in lung adenocarcinoma. Genes Dev. Published online Jun 2025.
• Essel Dadzie H, Green YS, Camolotto S, et al. HNF4α controls growth, identity and response to KRAS inhibition of invasive mucinous adenocarcinoma of the lung (preprint). bioRxiv. 2025:2025.06.06.658155.
• Cai L, Wu F, Zhou Q, et al. The Lung Cancer Autochthonous Model Gene Expression Database enables cross-study comparisons of the transcriptomic landscapes across mouse models. Cancer Res. 2025;85(10):1769-1783.
• Gillis K, Orellana WA, Wilson E, et al. FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma. Dev Cell. 2025;60(3):472-489.e8.
• Ghazi PC, OToole KT, Srinivas Boggaram S, et al. Inhibition of ULK1/2 and KRAS^G12C controls tumor growth in preclinical models of lung cancer. Elife. 2024;13:RP96992.
• Stuart WD, Ito M, Baldauf IF, et al. Patho-transcriptomic analysis of invasive mucinous adenocarcinoma of the lung (IMA): comparison with lung adenocarcinoma with signet ring cell features (SRCC) (preprint). bioRxiv. 2024:2024.06.13.598839.
• Orstad G, Fort G, Parnell TJ, et al. FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma. Dev Cell. 2022;57(15):1866-1882.e10.
• Ingram K, Samson SC, Zewdu R, et al. NKX2-1 controls lung cancer progression by inducing DUSP6 to dampen ERK activity. Oncogene. 2022;41(2):293-300.
• Zewdu R, Mehrabad EM, Ingram K, et al. An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma. Elife. 2021;10:e66788.
• Camolotto SA, Belova VK, Torre-Healy L, et al. Reciprocal regulation of pancreatic ductal adenocarcinoma growth and molecular subtype by HNF4α and SIX1/4. Gut. 2021;70(5):900-914.