Mary Bronner, MD

Specialties

• Gastrointestinal
• Hepatic and Pancreatic Pathology
• Molecular Oncologic Pathology

Education

• Medical Degree—University of Pennsylvania
• Residency—University of Pennsylvania

Certification/Affiliations

• Editorial Board Member, Human Pathology
• Editorial Board Member, Modern Pathology
• President, GI Pathology Society
• Council Member, United States and Canadian Academy of Pathology

Research Interests

• Basic, translational and clinical GI, hepatic and pancreaticobiliary pathology
• Molecular oncology

Awards

• The Arthur Purdy Stout Prize

Recent Publications

• *Sangle NA, et al. Overdiagnosis of high-grade dysplasia in Barrett's esophagus: a multicenter, international study. Mod Pathol. 2015;28(6):758–65.
• Krah NM, et al. The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma. 2015;4:e07125.
• Runtsch MC, et al. MicroRNA-146a constrains multiple parameters of intestinal immunity and increases susceptibility to DSS colitis. 2015;6(30):28556–72.
• Kanth P, et al. Gene signature in sessile serrated polyps identifies colon cancer subtype. Cancer Prev Res. 2016;9(6):456–65.
• Shaco-Levy R, et al. Morphologic characterization of hamartomatous gastrointestinal polyps in Cowden syndrome, Peutz-Jeghers syndrome, and juvenile polyposis syndrome. Hum Pathol. 2016;49:39–48.
• Lynam-Lennon N, et al. Low miR-187 expression promotes resistance to chemoradiation therapy in vitro and correlates with treatment failure in patients with esophageal adenocarcinoma. Mol Med. 2016;22:388–97.
• Underhill HR, et al. Fragment length of circulating tumor DNA. PLoS Genet. 2016;12(7):e1006162.
• Lin J, et al. Novel microRNA signature to differentiate ulcerative colitis from Crohn’s disease: A genome-wide study using next generation sequencing. Microrna. 2016;5(3):222–9.
• Shaco-Levy R, et al. Gastrointestinal polyposis in Cowden syndrome. J Clin Gastroenterol. 2017;51(7):e6–7.
• Samadder NJ, et al. Colorectal cancer in inflammatory bowel diseases: A population-based study in Utah. Dig Dis Sci. 2017;62(8):2126–32.
• *Lloyd IE, et al. A Clinicopathologic Evaluation of Incidental Fundic Gland Polyps With Dysplasia: Implications for Clinical Management. Am J Gastroenterol. 2017;112(7):1094–102.
• Cotton CC, et al. Late recurrence of Barrett's esophagus after complete eradication of intestinal metaplasia is rare: final report from ablation in intestinal metaplasia containing dysplasia trial. 2017;153(3):681–8.
• El Jabbour T, et al. PD-L1 protein expression in tumour cells and immune cells in mismatch repair protein-deficient and –proficient colorectal cancer: the foundation study using the SP142 antibody and whole section immunohistochemistry. J Clin Pathol. 2018;71(1):46–51.
• Schell JC, et al. Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism. Nat Cell Biol. 2017;19(9):1027–35.
• *Caliskan A, et al. Intramucosal lipomas of the colon implicate Cowden syndrome. Mod Pathology. 2018;31(4):643–51.
• Jedrzkiewicz J, et al. Liver fibrosis quantification by digital whole slide imaging and two photon microscopy with second harmonic generation. Int J of Pathol Clin Res. 2018;4:078.
• Russell CW, et al. Context-dependent requirements for FimH and other canonical virulence factors in gut colonization by extraintestinal pathogenic Escherichia coli. Infect Immun. 2018;86(3).
• Hellwig S, Nix DA, Gligorich KM, O'Shea JM, Thomas A, Fuertes CL, Bhetariya PJ, Marth GT, Bronner MP, Underhill HR. Automated size selection for short cell-free DNA fragments enriches for circulating tumor DNA and improves error correction during next generation sequencing. PLoS One. 2018;13(7):e0197333.
• Kanth P, et al. Small RNA sequencing of sessile serrated polyps identifies microRNA profile associated with colon cancer. Genes Chromosomes Cancer. 2019;58(1):23–33.

* Resident/Fellow/Graduate students supervised by Dr. Bronner.