Posters and Presentations
Each year, the ARUP Institute for Clinical and Experimental Pathology® presents at more than 200 conferences, workshops, annual meetings, and symposiums for several national and international organizations. Recent posters and presentations are listed below.
United States and Canadian Academy of Pathology (USCAP)
San Antonio, TX, March 4–10, 2017
Patel JL, Schumacher JA, Kelley TW—Presentation
Patel JL, Schumacher JA, Frizzell K, Sorrells S, Shen W, Clayton A, Jattani R, Kelley TW. Coexisting and cooperating mutations in NPM1-mutated AML.
Matynia A, Li D, Schumacher JA, Szankasi P, Kelley TW—Poster
Matynia A, Li D, Schumacher JA, Szankasi P, Kelley TW. “Molecular fingerprinting” of anatomically and temporally distinct B-cell lymphoma samples by next generation sequencing to establish clonal relatedness.
Salama M, Patel J, Agarwal AM—Poster
Cunningham AM, Salama M, Patel J, Agarwal AM. Phenotypic trends within genomic classifications of acute myeloid leukemia.
Tripp S, Reading NS, Salama M, Miles R—Poster
Soto LR, Glenn MJ, Tripp S, Reading NS, Salama M, Miles R. CD30 expression by RNA level but not by PAX5/CD30 double stain is associated with worse outcomes in diffuse large B-cell lymphoma.
American College of Medical Genetics and Genomics (ACMG)
Phoenix, AZ, March 21–25, 2017
Andersen EF, Toydemir R, Hong B—Poster
Paulraj P, Diamond S, Razzaqi F, Ozeran F, Andersen EF, Toydemir R, Hong B. Three pediatric acute myeloid leukemia patients with t(7;21)(p22;q22) and utility of genomic microarray analysis in detecting additional clonal aberrations.
Paulraj P, Palumbos J, Openshaw A, Carey J, Toydemir R. Interstitial deletion 6q25.2q26 associated with severe phenotypic features, congenital anomalies and global developmental delay.
Yuzyuk T, De Biase I—Poster
Gasparini J, Ortega A, Yuzyuk T, De Biase I. Perceived self-efficacy of genetic counselors as teachers.
Pham H, Pont-Kingdon G, Lyon E—Poster
Poster Brown S, Pham H, Pont-Kingdon G, Lyon E. Additional testing can aid interpretation of SMN1 and SMN2 copy number for patients with gene conversions.
Ha Y, Pham HT, Pont-Kingdon G, Lyon E—Poster
Poster Ha Y, Pham HT, Sibio S, Monds C, Pitchford J, Braten B, Meadows C, Miller C, Pont-Kingdon G, Lyon E. Implementation of the cystic fibrosis 165-pathogenic variant panel by QuantStudio™ 12K Flex OpenArray®.
Millson A, Morris AD, Paul EG, Lamb AN, Lyon E—Poster
Poster Millson A, Xiong W, Mikelson A, Morris AD, Paul EG, Lachowsky DR, LaGrave D, Lamb AN, Lyon E, Kusukawa N. Noninvasive prenatal testing for aneuploidy.
Poster Herriges JC, Brown S, Ozmore J, Janze A, Meck J, Andersen EF. The first clinical reports of 14q32 deletions that encompass DICER1 and are associated with DICER1-related tumor development.
Clinical Immunology Society (CIS)
Seattle, WA, March 23–26, 2017
Close DW, Kumánovics A—Poster
Patel B, Niebur H, Grana NH, Berman DM, Tuite GF, Close DW, Kumánovics A, Leiding JW. Evolution of immunodeficiency in a patient with kabuki syndrome.
Close DW, Kumánovics A—Poster
Sriaroon P, Chang Y, Ujhazi B, Csomos K, Joshi H, Zhou Q, Close DW, Armanios M, Walter JE, Kumánovics A. Thrombocytopenia as initial presentation of ikaros deficiency associated with a novel IKZF1 mutation.
Park City Anatomic Pathology Update
Park City, UT, February 6–10, 2017
Smock KJ. Update on anticoagulants monitoring practice.
Mass Spectrometry: Applications to the Clinical Lab (MSACL)
Palm Springs, CA, January 22–26, 2017
Ray JA, Rasmussen N, Strathmann FG—Poster
Ray JA, Golsan H, Rasmussen N, Strathmann FG. A proposed strategy for the detection of metabolic disorders: high resolution screening with reflex to targeted quantitation by tandem mass spectrometry.
Kushnir MM, Strathmann FG—Poster
Kushnir MM, Strathmann FG. A new look at parathyroid hormone-related protein (PTHrP): possible role for calcium regulation in brain.
Kushnir MM, Rockwood AL—Poster
Hattan SJ, Parker KC, Vestal ML, Kushnir MM, Rockwood AL. Large-scale study of glycated hemoglobin levels using dried blood spots and MALDI-TOF mass spectrometry.
Song B, Frank E—Poster
Song B, Frank E. Development and validation of a high-throughput quantitative method for determination of vitamin B6 in serum and plasma using LC-MS/MS.
Parker RL, Strathmann FG—Poster
Parker RL, Strathmann FG. Development of a twelve element panel in urine using an automated, 96-well based ICP-MS workflow.
Merrigan SD, Johnson-Davis KL—Poster
Merrigan SD, Powers JL, Johnson-Davis KL. LC-MS/MS method for quantitative analysis of clozapine, its major metabolites (norclozapine and clozapine N-oxide), and trazodone in serum or plasma.
Clark ZD, Barker A, Strathmann FG—Poster
Clark ZD, Barker A, Strathmann FG. Intelligent design of a toxicology panel: let chemistry be your guide.
American Federation for Medical Research: Western Medical Research Conference (AFMR-WMRC)
Carmel, CA, January 26–28, 2017
Martins TB, Slev PR, Hill HR—Poster
Martins TB, Wilcock DM, Firszt R, Slev PR, Hill HR. Evaluation of a basophil activation flow cytometric assay as an alternative to oral food challenge for determining peanut allergy.
American Society of Hematology (ASH)
San Diego, CA, December 3–6, 2016
Shah BN, Thuma PE, Reading NS, DelBove J, Prchal JT, Gordeuk VR. Host genetic factors in glucose-6-phosphate dehydrogenase and cytochrome b5 reductase 3 affect the susceptible of developing severe malarial anemia.
Agarwal AM, Reading NS, Salama ME, Patel JL—Poster
Agarwal AM, Reading NS, Frizzell K, Shen W, Sorrells S, Salama ME, Patel JL. Novel mutations identified in inherited bone marrow failure syndromes by next-generation sequencing.
Agarwal AM, Reading NS, Salama M, Patel JL—Poster
Agarwal AM, Reading NS, Kimberly F, Shen W, Sorrells S, Salama M, Prchal J, Yaish H, Patel JL, Christensen R. Insight into molecular basis of hemolytic anemia.
Reading NS, Agarwal AM, Salama ME—Poster
Reading NS, Agarwal AM, Hoffman R, Prchal JT, Salama ME. Transcriptional characterization of myelofibrotic bone marrow microenvironment reveals distinct tumor microenvironment in JAK2+ and CALR+ PMF marrows.
Miles RR. Microrna (miR)-17-92 contributes to therapy resistance in Burkitt lymphoma cells.
Association for Molecular Pathology (AMP)
Charlotte, NC, November 10–12, 2016
Reading NS, Sirdah MM, Shubair ME, Nelson BE, Al-Kahlout MS, Al-Tayeb JM, Aboud L, Shaban MA, Luzzatto L, Prchal JT. Clinical significance of G6PD variants among Palestinians.
Raney JA, Bastien RRL, Bernard P, Grossmann A, Matynia A, Samowitz WS, Bronner M, Vaughn CP—Poster
Raney JA, Bastien RRL, Pasi A, Wilson A, Geiersbach K, Bernard P, Grossmann A, Matynia A, Samowitz WS, Bronner M, Vaughn CP. Lessons learned in the clinical lab: factors affecting successful library construction of FFPE samples for somatic mutation detection.
Schumacher JA, Szankasi P, Kelley TW, Patel JL—Poster
Schumacher JA, Szankasi P, Frizzell K, Sorrells S, Shen W, Kelley TW, Patel JL. Comparison of real-time quantitative PCR and digital droplet PCR for detection of NPM1 type A transcripts.
Hall AH, Hellwig S, Gligorich K, Bronner M—Poster
Hall AH, Baker DN, Kennedy B, Fuertes C, Hellwig S, Gligorich K, Bronner M. A next-generation sequencing panel for low frequency mutations in circulating tumor DNA.
Margraf RL, Rindler PM, Bastien RRL, Raney R, Vaughn CP, Bernard P, Matynia A, Grossmann A, Bronner M, Samowitz WS—Poster
Margraf RL, Rindler PM, Bastien RRL, Raney R, Vaughn CP, Durtschi JD, Bolia A, Nix D, Gee E, Geiersbach KB, Bernard P, Matynia A, Grossmann A, Bronner M, Samowitz WS. Comprehensive solid tumor panel.
Longhurst MC, Rodgers GM, Andersen EF—Poster
Longhurst MC, Salama S, VanNess M, Kovascovics TJ, Rodgers GM, Shami PJ, Deininger MW, South ST, Andersen EF. Increased sensitivity for detection of genomic abnormalities from plasma cell-free DNA in myelodysplastic syndromes by SNP-array.
Szankasi P, Schumacher JA, Patel JL, Kelley TW—Poster
Brown AF, Parnell T, Szankasi P, Schumacher JA, Shen W, Frizzell K, Sorrells S, Patel JL, Kelley TW. Next-generation sequencing-derived variant allele frequencies underestimate the FLT3-ITD mutation burden: implications for risk stratification.
Paxton CN, Szankasi P, Schumacher JA, Sederberg M, Patel JL, Toydemir R, Kelley TW, Xu X—Poster
Shen W, Paxton CN, Szankasi P, Durtschi J, Schumacher JA, Sederberg M, Frizzell KA, Sorrells SM, Patel JL, Toydemir R, Kelley TW, Xu X. Concurrent detection of genome-wide copy number variants and targeted somatic mutations in hematologic malignancies using next-generation sequencing.
Szankasi P, Schumacher JA, Patel JL, Kelley TW—Poster and Presentation
Szankasi P, Bolia A, Gee EP, Schumacher JA, Patel JL, Kelley TW. Comprehensive detection of balanced translocations in B-cell lymphoproliferative disorders by massively parallel sequencing.
American College of Rheumatology (ACR)
Washington, DC, November 11–16, 2016
Haven TR, Tebo AE—Poster
Haven TR, Hersh AO, Muscal E, Tebo AE. Autoantibody diversity in pediatric patients undergoing evaluation for autoimmune encephalitis: a retrospective investigation.
Peterson LK, Jaskowski TD, Tebo AE—Poster
Peterson LK, Jaskowski TD, Tebo AE. Antibodies to small ubiquitin-like modifier activating enzyme: frequency and characteristics of antibody-positive patients in an unselected cohort.
American Society of Human Genetics (ASHG)
Vancouver, Canada, October 18–22, 2016
Wooderchak-Donahue W, Margraf R, Bayrak-Toydemir P—Poster
Wooderchak-Donahue W, Tu JH, Margraf R, Le J, Bayrak-Toydemir P, Teng JM. Genetic analysis of vascular malformations reveals both germline and somatic mutations.
Sumner KL, Best DH—Poster
Sumner KL, Best DH. Retrospective comparison of traditional single gene testing and massively parallel sequencing-based gene panels in the diagnosis of pulmonary arterial hypertension.
Close DW, Reading NS, Pont-Kingdon G, Vaughn CP, Voelkerding KV, Kumanovics A—Poster
Close DW, Reading NS, Pont-Kingdon G, Vaughn CP, Voelkerding KV, Kumanovics A. Overcoming the challenges of regions of high homology in the clinical genomics laboratory using short-read based next-generation sequencing platforms.
Society of Forensic Toxicologists (SOFT)
Dallas, TX, October 16–21, 2016
Taylor LL, Strathmann F—Poster
Taylor LL, Flint NA, Ma V, Hill BM, Clark CJ, Strathmann FG. Use of an internal hydrolysis indicator for monitoring β-glucuronidase activity.
HHT National Patient & Family Conference
Boston, MA, October 28–30, 2016
Wooderchak-Donahue W, Jama M, Bayrak-Toydemir P—Poster
Wooderchak-Donahue W, Chen T, McDonald J, Whitehead K, Jama M, Bayrak-Toydemir P. Identification of new genes and genetic modifiers in HHT.
European Association for Haematopathology (EAH)
Basel, Switzerland, September 3–8, 2016
Reading NS. Characterization of the bone marrow microenvironment using NanoString nCounter analysis of formalin-fixed paraffin-embedded specimens from the PMF patients.
National Society of Histotechnology (NSH)
Long Beach, CA, September 16–21, 2016
Tripp SR, Salama ME—Poster
Tripp SR, Rets A, Salama ME. The utility of a monoclonal antibody for immunohistochemical detection of calreticulin mutations in bone marrow biopsies from patients with myeloproliferative neoplasms.
International Clinical Cytometry Society (ICCS)
Bonita Springs, FL, September 30–October 4, 2016
Ravkov E, Heikal N—Poster
Ravkov E, Jolly B, Andreasen J, Heikal N. Platelet glycoprotein expression in whole blood: validation of major test parameters.