QuantiFERON-TB Gold Plus

quantiferon graphic

Available May 21, 2018

ARUP is the only reference laboratory that offers QuantiFERON-TB Gold Plus with two blood collection options:

QuantiFERON-TB Gold Plus, 1-Tube (ARUP test code 3000400) (QFT-PLUS)

  • Collect 6 mL (5 mL min) of whole blood drawn into an ARUP provided single lithium-heparin tube (ARUP supply # 54015). See Collection tab for more information.

QuantiFERON-TB Gold Plus, 4-Tube (ARUP test code 3000399) (QFT-4)

Client supplies are currently available; lithium-heparin tubes or 4-tube collection pack on eSupply or call ARUP Client Services at (800) 522-2787.

The single lithium-heparin collection tube option (3000400) offers the most convenience to clients. A single lithium-heparin specimen is collected, incubated at room temperature for a minimum of 15 minutes and then shipped refrigerated to ARUP Laboratories, where all further pre-analytic specimen processing is conducted. The single lithium-heparin specimen should be sent to ARUP the same day it is collected in order to avoid exceeding the 48 hour stability. We encourage clients to order QuantiFERON-TB Gold Plus electronically through their LIS or ARUPConnect. View the interface map here.

If the client cannot send specimens the same day they are collected, then ARUP recommends the QuantiFERON-TB Gold Plus, 4-Tube assay (3000399). The 4-tube assays requires the same pre-analytical processing steps as the current 3-tube QuantiFERON-TB Gold assay.

The new QuantiFERON-TB Gold Plus assays use the same principles, test procedures as the current assay, but is optimized with tuberculosis-specific antigens that elicit both CD8+ and CD4+ T cell responses –enabling a more comprehensive assessment of cell-mediated immune response to TB infection.


The QuantiFERON-TB Gold (0051729) assay will be available concurrently with the two new assays for a short period. Clients may continue to order and submit QuantiFERON-TB Gold specimens (3-tubes) until August 20, 2018, the official inactivation date, or until the supply of collection tubes is exhausted at ARUP.

For more questions, contact ARUP Client Services at (800) 522-2787, keyword: quantiferon.